Results 41 to 50 of about 28,139,738 (307)

C2-Alkylation of N-pyrimidylindole with vinylsilane via cobalt-catalyzed C–H bond activation

Beilstein Journal of Organic Chemistry, 2012
Direct C2-alkylation of an indole bearing a readily removable N-pyrimidyl group with a vinylsilane was achieved by using a cobalt catalyst generated in situ from CoBr2, bathocuproine, and cyclohexylmagnesium bromide.
Zhenhua Ding, Naohiko Yoshikai
doaj   +1 more source

Electroreductive Deoxygenative C–H and C–C Bond Formation from Non-Derivatized Alcohols Fueled by Borohydride Oxidation [PDF]

, 2023
Alcohols are one of the most common organic compound classes among natural and synthetic products. Thus, methods for direct removal of C–OH groups without the need for wasteful pre-functionalization are of great synthetic interest to unlock the full ...
Hemlata, Agarwala, Adrian, Soto Kronberg, Victoria, Chu, Mårten, Ahlquist, Piret, Villo, Guillermo, Ahumada, Helena, Lundberg, Malin, Lill, Zainab, Alsaman   +8 more
core   +1 more source

C–H Bond Activation at Palladium(IV) Centers [PDF]

Journal of the American Chemical Society, 2011
This communication describes the first observation and study of C-H activation at a Pd(IV) center. This transformation was achieved by designing model complexes in which the rate of reductive elimination is slowed relative to that of the desired C-H activation process.
Joy M, Racowski, Nicholas D, Ball, Melanie S, Sanford   +2 more
openaire   +2 more sources

Silver-Mediated Direct sp(3) C-H Bond Functionalization

, 2015
Direct sp(3) C-H bond functionalization is an efficient, straightforward, and powerful method to construct new C-X (X = C, N, F, S) bonds from nonfunctionalized aliphatic motif of organic molecules, which has been used in late-stage modification of ...
Zhou, Taigang, Zhang-Jie Shi, Shi, Zhang-Jie, Taigang Zhou   +3 more
core   +1 more source

Synthesis of C70-fragment buckybowls bearing alkoxy substituents

Beilstein Journal of Organic Chemistry, 2020
Buckybowls bearing a C70 fragment having two alkoxy groups were synthesized and their structural and optical properties were investigated by single crystal X-ray analysis and UV–vis spectroscopy. In the synthesis of dioxole derivative 5b, the regioisomer
Yumi Yakiyama, Shota Hishikawa, Hidehiro Sakurai   +2 more
doaj   +1 more source

Selectivity of C–H Activation and Competition between C–H and C–F Bond Activation at Fluorocarbons [PDF]

Chemical Reviews, 2017
Partially fluorinated alkanes, arenes, and alkenes can be transformed by a variety of transition metal and lanthanide systems. Although the C-H bond is weaker than the C-F bond regardless of the hybridization of the carbon, the reaction of the C-F bond at the metal is usually more exothermic than the corresponding reaction of the C-H bonds.
Odile Eisenstein, Jessica Milani, Robin N. Perutz   +2 more
openaire   +3 more sources

Heterolytic bond activation at gold: Evidence for gold(III) H-B, H-Si complexes, H-H and H-C cleavage [PDF]

, 2019
The coordinatively unsaturated gold(III) chelate complex [(C^N-CH)Au(C6F5)]+ (1+) reacts with main group hydrides H-BPin and H-SiEt3 in dichloromethane solution at 70 °C to form the corresponding σ-complexes, which were spectroscopically characterized (C^
Budzelaar, Peter, Bochmann, Manfred, Bochmann M., Rocchigiani L., Budzelaar P. H. M., Rocchigiani, Luca   +5 more
core   +1 more source

Cobalt-catalyzed directed C–H alkenylation of pivalophenone N–H imine with alkenyl phosphates

Beilstein Journal of Organic Chemistry, 2018
A cobalt–N-heterocyclic carbene (NHC) catalyst efficiently promotes an ortho C–H alkenylation reaction of pivalophenone N–H imine with an alkenyl phosphate. The reaction tolerates various substituted pivalophenone N–H imines as well as cyclic and acyclic
Wengang Xu, Naohiko Yoshikai
doaj   +1 more source

Tracking C-H activation with orbital resolution [PDF]

, 2023
The reactivity towards C-H bond activation of alkanes with transition metals is determined by the ability of the metal to donate and withdraw electron density in due proportion.
Dmitry, Ozerov, Torsten, Leitner, Christopher, Arrell, Raphael, Jay, Victoria, Kabanova, Philip, Johnson, Jessica, Harich, Camila, Bacellar, Ambar, Banerjee, Christopher, Milne, Nils, Huse, Grigory, Smolentsev, Michael, Coates, Anna, Wach, Claudio, Cirelli, Michael, Odelius, Robert, Stefanuik, Camelia, Borca, Ru-Pan, Wang, Thomas, Huthwelker, Hampus, Wikmark, Abdullah, Kahraman, Emma, Beale, Philippe, Wernet   +23 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source