Results 21 to 30 of about 23,038 (267)

Introducing Ion Mobility Mass Spectrometry to Identify Site-Selective C–H Bond Activation in N-Heterocyclic Carbene Metal Complexes [PDF]

, 2022
The activation of C−H bonds in a selective manner still constitutes a major challenge from a synthetic point of view; thus, it remains an active area of fundamental and applied research. Herein, we introduce ion mobility spectrometry mass spectrometry-
Ibañez-Ibañez, Laura, Mata Martínez, Jose A, Guisado‐Barrios, Gregorio, Gregorio Guisado-Barrios, Laura Ibáñez-Ibáñez, Cristian Vicent, Mollar-Cuni, Andrés, Jose A. Mata, Vicent, Cristian, Andrés Mollar-Cuni, Mollar Cuni, Andrés, Mata, José A., Guisado-Barrios, Gregorio, Vicent Barrera, Cristian   +13 more
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Transition Metal-catalyzed C-H /C-C Activation and Coupling with 1, 3-diyne

, 2022
This review focuses on providing a broad overview of the recent developments in the field of transition metal-catalyzed C-H bond activation and coupling with 1,3-diyne for assembling alkynylated heterocycles and bis-heterocycles.
Tanmayee, Nanda, Ponneri C., Ravikumar, Nitha Nahan, Puthalath, Shyam Kumar , Banjare, Bedadyuti Vedvyas, Pati   +4 more
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Ligand Accelerated Hydrogen Isotope Exchange: Switching C-H Activation from Functionalization Towards C-D Bond Formation

, 2023
Hydrogen isotope exchange (HIE) has emerged as a unique strategy for labelling, affording plenty of deuterated chemicals with varieties in patterns.
Jianfei, Bai, Bencan, Tang, Dawei, Xu, Jiakai, Lu, Zhi-Jiang, Jiang, Zhanghua, Gao, Jia, Chen   +6 more
core   +1 more source

C–H Bond Activation at Palladium(IV) Centers [PDF]

Journal of the American Chemical Society, 2011
This communication describes the first observation and study of C-H activation at a Pd(IV) center. This transformation was achieved by designing model complexes in which the rate of reductive elimination is slowed relative to that of the desired C-H activation process.
Joy M, Racowski, Nicholas D, Ball, Melanie S, Sanford   +2 more
openaire   +2 more sources

Regioselective Pd-catalyzed direct C1- and C2-arylations of lilolidine for the access to 5,6-dihydropyrrolo[3,2,1-ij]quinoline derivatives

Beilstein Journal of Organic Chemistry, 2019
The Pd-catalyzed C–H bond functionalization of lilolidine was investigated. The use of a palladium-diphosphine catalyst associated to acetate bases in DMA was found to promote the regioselective arylation at α-position of the nitrogen atom of lilolidine ...
Hai-Yun Huang, Haoran Li, Thierry Roisnel, Jean-François Soulé, Henri Doucet   +4 more
doaj   +1 more source

C–H Functionalization via Iodine-mediated Electrocatalysis and C–N Bond Formation

, 2022
The access of heterocyclic compounds via direct amination of C-H bonds are of vital interest because of their role in pharmaceutical and natural products. The combination of molecular iodine and electricity activates benzylic C-H bond and facilitates the
Guilherme. M., Martins, Nisar, Ahmed
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Mechanistic Study of Ru-NHC-Catalyzed Hydrodefluorination of Fluoropyridines: The Influence of the NHC on the Regioselectivity of C–F Activation and Chemoselectivity of C–F versus C–H Bond Cleavage [PDF]

, 2015
We describe a combined experimental and computational study into the scope, regioselectivity, and mechanism of the catalytic hydrodefluorination (HDF) of fluoropyridines, C5F5–xHxN (x = 0–2), at two Ru(NHC)(PPh3)2(CO)H2 catalysts (NHC = IPr, 1, and IMes,
Whittlesey, Michael K., Stuart A. Macgregor, Stuart A. Macgregor (1350846), Mary F. Mahon (1293876), Mahon, M.F., Mary F. Mahon, McKay, D., Riddlestone, Ian M., Mahon, Mary F., Whittlesey, M.K., David McKay, Michael K. Whittlesey (1309881), Mckay, David, David McKay (1351782), Macgregor, S.A., Ian M. Riddlestone (1340919), Macgregor, Stuart A., Ian M. Riddlestone, Michael K. Whittlesey   +18 more
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Reversing the Regioselectivity of Asymmetric C ̶ H and N ̶ H Bond Annulation with Bromoalkynes Under Cobalt(III)-Catalysis

, 2023
Metal-catalyzed C-H bond annulation strategy offers a versatile platform, allowing the construction of complex p-chiral molecules through atom- and step-economical fashion. However, regioselective insertion of -coupling partner between M-C bond and high
Subramani , Kumaran, Harihara , Subramanian, basker, sundararaju, Rajib, Mandal, Abir , Das   +4 more
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C—H Activation of Unbiased C(sp3)—H Bonds

, 2022
The selective functionalization of non-activated C(sp3)—H bonds is a major challenge in chemistry. Here, we have developed an [Au]-catalyzed C(sp3)-H activation of common 1 bromoalkynes into a library of diverse 3D-scaffolds.
Pablo, Barrio, Nina, Semleit, José M., González, Rubén, Miguélez, Pavel, Mykhailiuk, Gebhard, Haberhauer, Carlos, Rodríguez-Arias   +6 more
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Recent Advances in the Synthesis of Cyclic Sulfoximines via C–H Bond Activation

Molecules, 2023
Sulfoximines, a ubiquitous class of structural motifs, are widely present in bioactive molecules and functional materials that have received considerable attention from modern organic chemistry, pharmaceutical industries, and materials science ...
Bingren Wang, Xiayu Liang, Qingle Zeng
doaj   +1 more source