Rhodium-Catalyzed C–H Bond Functionalization with Amides by Double C–H/C–N Bond Activation
Organic Letters, 2016 The first C-H bond functionalization with amides as the coupling partners via selective activation of the amide N-C bond using rhodium(I) catalysts under highly chemoselective conditions is reported. Notably, this report constitutes the first catalytic activation of the amide N-C(O) bond by rhodium.
Guangrong, Meng, Michal, Szostak
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Lowering the C-H Bond Activation Barrier of Methane Using SAC@Cu(111): A Periodic DFT Investigations [PDF]
, 2021 Methane has long captured the world\u27s spotlight for being the simplest and yet one of the most notorious hydrocarbon. Exploring its potential to be converted into value added products has raised a compelling interest.
Meema, Bhati +2 more
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Tandem C–O and C–H Activation at Palladium Enables Catalytic Direct C–H Alkenylation with Enol Pivalates [PDF]
, 2021 The use of oxygen-based electrophiles in cross-coupling remains challenging for substrates with strong C–O bonds, with few examples that can combine C–O activation with an-other strong-bond activation in tandem.
Nahiane, Pipaon Fernandez +4 more
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δ-C(sp3)H Activation of Free Alcohols Enabled by Rationally Designed H-Bond-Acceptor Ligands [PDF]
, 2023 The ability to employ a wide range of native substrates is essential for the broad application of transition-metal-catalyzed C–H activation. Recent advances have made native carboxylic acids, ketones, and amines amenable to C(sp3)–H activation, but ...
Jin-Quan, Yu +9 more
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C-H Bond Activation via Concerted Metalation-Deprotonation at a Palladium(III) Center [PDF]
, 2022 Herein we report the direct observation of C-H bond activation at an isolated mononuclear Pd(III) center. The oxidation of the Pd(II) complex (MeN4)PdII(neophyl)Cl (neophyl = -CH2C(CH3)2Ph; MeN4 = N,N′-di-tert-butyl-2,11-diaza[3.3](2,6)pyridinophane ...
Dae Young, Bae +7 more
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C—H Activation of Unbiased C(sp3)—H Bonds [PDF]
, 2022 The selective functionalization of non-activated C(sp3)—H bonds is a major challenge in chemistry. Here, we have developed an [Au]-catalyzed C(sp3)-H activation of common 1 bromoalkynes into a library of diverse 3D-scaffolds.
Pablo, Barrio +6 more
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Dehydrogenative Double C-H Bond Activation in a Germylene-Rhodium Complex*. [PDF]
Chemistry, 2021 Abstract Transition metal tetrylene complexes offer great opportunities for molecular cooperation due to the ambiphilic character of the group 14 element. Here we focus on the coordination of germylene [(Ar Mes2 ) 2 Ge :] (Ar
Bajo S +3 more
europepmc +8 more sources
Metal Nanoparticles as Sustainable Tools for C–N Bond Formation via C–H Activation
Molecules, 2021 The design of highly active metal nanoparticles to be employed as efficient heterogeneous catalysts is a key tool for the construction of complex organic molecules and the minimization of their environmental costs.
Federica Valentini +2 more
doaj +1 more source
Strain Release in CH Bond Activation? [PDF]
Angewandte Chemie, 2009 What a relief! In 1955 the principle of strain release was put forward to explain the differing reactivity of axial and equitorial alcohols during oxidation. Our findings suggest that this same rationale may account for the differing rates of activation between axial and equitorial C–H bonds in C–H activation processes.
Chen, Ke +2 more
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Ligand Accelerated Hydrogen Isotope Exchange: Switching C-H Activation from Functionalization Towards C-D Bond Formation [PDF]
, 2023 Hydrogen isotope exchange (HIE) has emerged as a unique strategy for labelling, affording plenty of deuterated chemicals with varieties in patterns.
Jianfei, Bai +6 more
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