Results 111 to 120 of about 81,063 (242)

Blimp-1 and c-Maf regulate  <i>Il10 and </i>negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells. [PDF]

Wellcome Open Res, 2023
Cox LS, Alvarez-Martinez M, Wu X, Gabryšová L, Luisier R, Briscoe J, Luscombe NM, O'Garra A.   +7 more
europepmc   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Modulation of growth, microcystin production, and algal-bacterial interactions of the bloom-forming algae Microcystis aeruginosa by a novel bacterium recovered from its phycosphere

Frontiers in Microbiology
Harmful algal blooms (HABs) in natural waters are of escalating global concern due to their detrimental impact on environmental health. Emerging evidence indicates that algae-bacteria symbionts can affect HAB features, though much about this interplay ...
Yao Xiao, Mijia Du, Yang Deng, Qinglin Deng, Xin Wang, Yiwen Yang, Binghuo Zhang, Yu-Qin Zhang   +7 more
doaj   +1 more source

Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction. [PDF]

Cell Stem Cell, 2022
Gómez-Salinero JM, Izzo F, Lin Y, Houghton S, Itkin T, Geng F, Bram Y, Adelson RP, Lu TM, Inghirami G, Xiang JZ, Lis R, Redmond D, Schreiner R, Rabbany SY, Landau DA, Schwartz RE, Rafii S.   +17 more
europepmc   +1 more source

Proximal Fibular Osteotomy: A Refined Surgical Technique for Medial Compartment Knee Osteoarthritis

Arthroscopy Techniques, EarlyView.
Abstract Proximal fibular osteotomy is a minimally invasive and cost‐effective option for medial compartment knee osteoarthritis. This refined technique, performed under spinal anesthesia using Henry's posterolateral approach, involves a small incision approximately 10 cm distal to the fibular head, careful dissection through the peroneus longus plane,
Mohammad Ayati Firoozabadi, Mohammad Rastegar, Pouya Tabatabaei Irani, Rahmatullah Azimi, Armin Akbarzadeh, Seyed Mohammad Javad Mortazavi   +5 more
wiley   +1 more source

Angiocatheter‐Assisted All‐Inside Repair of Meniscal Ramp Lesions: A Simple and Cost‐Effective Technique

Arthroscopy Techniques, EarlyView.
Abstract Ramp lesions of the medial meniscus are frequently associated with anterior cruciate ligament injuries and contribute to persistent instability if untreated. Diagnosis is challenging, and repair techniques often require posteromedial portals or specialized devices.
Mohammad Ayati Firoozabadi, Mohammad Rastegar, Pouya Tabatabaei Irani, Rahmatullah Azimi, Armin Akbarzadeh, Seyed Mohammad Javad Mortazavi   +5 more
wiley   +1 more source

c-Maf enforces cytokine production and promotes memory-like responses in mouse and human type 2 innate lymphoid cells. [PDF]

EMBO J, 2022
Trabanelli S, Ercolano G, Wyss T, Gomez-Cadena A, Falquet M, Cropp D, Imbratta C, Leblond MM, Salvestrini V, Curti A, Adotevi O, Jandus C, Verdeil G.   +12 more
europepmc   +1 more source

Risk of venous thromboembolism after SARS‐CoV‐2 vaccination—Evidence from genome‐wide association study and population‐based observational study

British Journal of Clinical Pharmacology, EarlyView.
Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind, Niclas Eriksson, Marco Cavalli, Yiyi Xu, Fredrik Nyberg, Anders Sundström, Mia Wadelius, Pär Hallberg   +7 more
wiley   +1 more source

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

Differential metabolic requirement governed by transcription factor c-Maf dictates innate γδT17 effector functionality in mice and humans. [PDF]

Sci Adv, 2022
Chen X, Cai Y, Hu X, Ding C, He L, Zhang X, Chen F, Yan J.   +7 more
europepmc   +1 more source