Clinical Proficiency of Low Hemoglobin Density and Microcyte Anemia Factor Parameters for the Diagnosis of Functional Iron Deficiency from Absolute Iron Deficiency in Chronic Inflammation [PDF]
Introduction: Inflammatory conditions affect iron status due to inflammation-induced changes in acute-phase proteins. However, distinguishing between functional and absolute iron deficiency severity can aid early treatment, necessitating the exploration
Fatemeh Karamshahi +5 more
doaj
Abstract Objective To evaluate the diagnostic utility and genetic spectrum of next‐generation sequencing (NGS) in a large, well‐phenotyped cohort of Turkish pediatric patients with epilepsy of unknown etiology. Methods Between January 2021 and December 2024, 250 children (115 female, 135 male) with unexplained epilepsy underwent either whole‐exome ...
Derya Karaer +4 more
wiley +1 more source
Deletion of Cdk5 in Macrophages Ameliorates Anti-Inflammatory Response during Endotoxemia through Induction of C-Maf and Il-10. [PDF]
Pfänder P +3 more
europepmc +1 more source
Air pollution exposure during training impairs performance in Thoroughbred racehorses
Abstract Background Ambient air pollution contributes substantially to human morbidity and mortality, and athletes are recognised as a particularly vulnerable group. However, little is known about the impact of air pollution on equine athletes. Objectives To explore the relationship between air pollution exposure during the pre‐competition training ...
Danielle Scott +4 more
wiley +1 more source
c-Maf nuclear oncoprotein is frequently expressed in multiple myeloma [PDF]
Hong, Chang, Q, Qi, W, Xu, B, Patterson
openaire +2 more sources
Altered gene expression in the liver and small intestine of horses with equine neuroaxonal dystrophy
Abstract Background Equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM) is the second most common diagnosis of spinal ataxia in horses in the United States. The disease develops due to a combination of vitamin E deficiency and an unknown genetic risk factor(s), and there currently is no effective treatment.
Stephanie Ryan +4 more
wiley +1 more source
Using a wearable electrocardiogram (ECG) patch adapted for 7‐day monitoring in the horse
Abstract Background Arrhythmias can cause poor performance and sudden death in horses. Long‐term (>24 h) electrocardiogram (ECG) monitoring has been used to identify arrhythmias in humans and is superior to short‐term monitoring for transient arrhythmia detection. Televet is the current equine gold‐standard ECG device. The Cardea SOLO™ (CS) is a single‐
Tatiana Delecave Dias +3 more
wiley +1 more source
A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee +4 more
wiley +1 more source
USP5-C-MAF Axis Regulates Autophagy-Dependent Neuronal Ferroptosis in Spinal Cord Injury Therapeutics. [PDF]
Weng S, Wu K, Huang Y, Cao L, Fu H.
europepmc +1 more source
A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4+ T cells and is defective in Crohn´s disease patients. [PDF]
Ahlers J +17 more
europepmc +1 more source

