Results 81 to 90 of about 82,350 (159)
The roles of Irx3 and Irx5 in mammalian inner ear development [PDF]
Iroquois genes encode a family of transcription factors containing TALE class homeodomain. They are regarded as prepatterning genes in Drosophila sensory organ development. There are six members (Irx1Irx6) of Iroquois genes in mouse and human.
Chan, YS +6 more
core
Sufu defines the balance of hindbrain progenitor cells maintenance and differentiation [PDF]
Suppressor of fused (Sufu) was identified as a regulator in Hedgehog signalling. Study shown that Sufu knockout mice were embryonic lethal at E9.5, exhibiting cephalic deformities, open neural tube and ventralized spinal cord resulting from ectopic Shh ...
Hor, HH, Hui, CC, Sham, MH, Wang, XA
core
c-maf in multiple myeloma [PDF]
Kienast, Joachim, Berdel, Wolfgang E
openaire +1 more source
Identification and characterization of long-range SOX9 enhancers in limb development [PDF]
The transcription factor Sox9 is a master regulator of skeletogenesis. Heterozygous mutations of human SOX9 result in Campomelic Dysplasia (CD), in which affected individuals display distinct abnormalities in limbs and other skeletal assemblies. Recently,
Chan, D +5 more
core
c-maf in multiple myeloma: an oncogene enhancing tumor-stroma interactions.
Gene expression profiling studies reported by Hurt et al. in this issue of Cancer Cell reveal an unexpectedly frequent overexpression of c-maf in multiple myeloma and identify molecular targets of c-maf transactivation. The results define c-maf as a prototype of a class of oncogenes that not only stimulate cell cycle progression, but also promote ...
Kienast, Joachim, Berdel, Wolfgang E
openaire +2 more sources
Kinesin-1 is involved in chondrocytes adhesion to extracellular matrix and motility [PDF]
Intercalation movement of proliferative chondrocytes is crucial for their columnar organization which is essential for proper function of growth plate cartilage.
Chan, D +5 more
core
MMP14 regulates the lineage progression of hypertrophic chondrocytes [PDF]
It is traditionally believed that chondrocytes and osteoblasts are two separate lineages with hypertrophic chondrocytes (HCs) being the terminal stage of chondrocyte differentiation, culminating in apoptosis.
Cheah, KSE +4 more
core
Role of c-Maf in Chondrocyte Differentiation
Chondrocyte differentiation in the growth plate is an important process for the longitudinal growth of endochondral bones. Sox9 and Runx2 are the most often-studied transcriptional regulators of the chondrocyte differentiation process, but the importance of additional factors is also becoming apparent.
Hong, Eunmee +2 more
openaire +2 more sources
Background: Metabolic syndrome (MetS) comprises interrelated metabolic abnormalities that collectively confer increased risk of cardiovascular disease and hepatic morbidity.
Musa Salmanoğlu +5 more
doaj +1 more source
Effects of flavonoids from Martynia annua and Tephrosia purpurea on cutaneous wound healing [PDF]
Objective: Martynia annua L. (M. annua), (Martyniaccae) has been traditionally used in the treatment of epilepsy, sore throat and inflammatory disorders.
Santram Lodhi +4 more
doaj

