Results 61 to 70 of about 20,395,316 (257)

Maf and Mafb control mouse pallial interneuron fate and maturation through neuropsychiatric disease gene regulation

eLife, 2020
​Maf (c-Maf) and Mafb transcription factors (TFs) have compensatory roles in repressing somatostatin (SST+) interneuron (IN) production in medial ganglionic eminence (MGE) secondary progenitors in mice.
Emily Ling-Lin Pai, Jin Chen, Siavash Fazel Darbandi, Frances S Cho, Jiapei Chen, Susan Lindtner, Julia S Chu, Jeanne T Paz, Daniel Vogt, Mercedes F Paredes, John LR Rubenstein   +10 more
doaj   +1 more source

c-Maf is essential for the F4/80 expression in macrophages in vivo [PDF]

Gene, 2009
c-Maf, which is one of the large Maf transcription factors, can bind to Maf recognition element (MARE) and activates transcription of target genes. Although c-Maf is expressed in macrophages and directly regulates the expression of interleukin-10, detailed information regarding its function in the null mutant phenotype of tissue macrophages remain ...
Nakamura, M, Hamada, M, Hasegawa, K, Kusakabe, M, Suzuki, H, Greaves, D, Moriguchi, T, Kudo, T, Takahashi, S   +8 more
openaire   +3 more sources

Genetics in TNF-TNFR pathway: A complex network causing spondyloarthritis and conditioning response to anti-TNFα therapy. [PDF]

PLoS ONE, 2018
We investigated whether polymorphisms (SNPs) in the promoter region of TNFA, or in the autoinflammatory TNFRSF1A and MEFV genes, concur with HLA-B27 in enhancing the risk of Spondyloarthritis (SpA) and/or in predicting the response to anti-TNFα treatment.
Ada Aita, Daniela Basso, Roberta Ramonda, Stefania Moz, Mariagrazia Lorenzin, Filippo Navaglia, Carlo-Federico Zambon, Andrea Padoan, Mario Plebani, Leonardo Punzi   +9 more
doaj   +1 more source

Ni-doped metal-azolate framework-6 derived carbon as a highly active catalyst for CO2 conversion through the CO2 hydrogenation reaction

Carbon Capture Science & Technology, 2023
A profound and accelerated solution towards mitigating atmospheric CO2 levels and converting the CO2 to useful fuels and chemicals, such as CO or CH4, would be to utilize and promote the catalytic CO2 hydrogenation reaction.
Pradeep S. Murthy, Liam Wilson, Xingmo Zhang, Weibin Liang, Jun Huang   +4 more
doaj   +1 more source

IFN-α affects Th17/Treg cell balance through c-Maf and associated with the progression of EBV- SLE.

Molecular Immunology
OBJECTIVES Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disease, of which the pathogens is remains obscure. Viral infection, particularly Epstein Barr viru (EBV) infection, has been considered a common pathogenic factor.
Yue Zhang, Jia-Chao Wang, Ya-Qi Fang, Wen-Zhang Liang, Ling-Yan Lei, Jun-Hai Wang, Xue Gao, Cui-Qing Ma, Miao Li, Hui-Fang Guo, Lin Wei   +10 more
semanticscholar   +1 more source

Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic, Petr Dusek, Ibrahim Kamaci, Bahar Gulmez, Gul Yalcin Cakmakli, Ersin Tan, Sibel Ugur Iseri, Zuhal Yapici   +7 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

The role of interleukin 22 in multiple sclerosis and its association with c-Maf and AHR

Biomedical Papers, 2019
The aim of this paper was to summarise knowledge of IL-22 involvement in multiple sclerosis (MS) and the possible link between IL-22 and two transcription factors - AHR and c-Maf.
Michal Konrad Zarobkiewicz, Wioleta Kowalska, Miroslaw Slawinski, Jacek Rolinski, Agnieszka Bojarska-Junak   +4 more
doaj   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Wear mechanism transforming of ultrafine-grained pure titanium by multi-axial forging and low-temperature annealing

Journal of Materials Research and Technology
The effect of microstructure and mechanical properties of submicro grained commercial pure titanium (CP–Ti) on the wear mechanism is still unclear.
Rongyou Chen, Shubo Guo, Xiaolian Zhao, Yutang Yin, Sijie Du, Yang Song, Wei Liang, Aoke Jiang, Yiting He, Chunhua Wei   +9 more
doaj   +1 more source