Results 51 to 60 of about 20,395,316 (257)
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
Frontiers in Immunology, 2020 RORγt-expressing Tregs form a specialized subset of intestinal CD4+ Foxp3+ cells which is essential to maintain gut homeostasis and tolerance to commensal microbiota.
Hind Hussein +9 more
doaj +1 more source
Geosciences, 2021 The Cenomanian Mata Amarilla Formation (MAF) in southern Patagonia (~55° S paleolatitude, Austral-Magallanes Basin, Argentina) is composed mainly of stacked fluvial deposits with intercalated paleosols, which document Cenomanian environments at high ...
Augusto Nicolás Varela +5 more
doaj +1 more source
c-Maf and you won’t see fat [PDF]
Journal of Clinical Investigation, 2010 Osteoporosis is a common, age-related bone disease that results from an imbalance between the processes of bone formation and bone resorption, resulting in reduced bone mass and increased risk of fracture. Mesenchymal stem cells have the capacity to differentiate into osteoblastic and adipogenic lineages; recent research suggests that the switch ...
openaire +2 more sources
Evolution of microstructure and mechanical properties of Ti-based metal-matrix composites during hot deformation [PDF]
MATEC Web of Conferences, 2020 Two Ti-based composites, viz. Ti/TiB and Ti-15Mo/TiB were produced by spark plasma sintering using a Ti-10wt.%TiB2 powder mixture at 1000°C or Ti-14.25(wt.)%Mo-5(wt.)%TiB2 powder mixture at 1400°C, respectively.
Zherebtsov S. +5 more
doaj +1 more source
The transcription factor c-Maf in sensory neuron development [PDF]
Transcription, 2012 The proto-oncogene c-Maf has been shown to be an important transcriptional regulator in the differentiation of a number of cellular contexts, like the eye and hematopoietic system. Here we discuss the recent progress made in understanding c-Maf function in the nervous system.
Hagen, Wende +2 more
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Haematologica, 2007 Background and Objectives BAFF and APRIL stimulate the growth of multiple myeloma (MM) cells. BAFF and APRIL share two receptors – TACI and BCMA – and BAFF binds to a third receptor, BAFF-R.
Jérôme Moreaux +10 more
doaj +1 more source
Clinical implications of c-maf expression in plasma cells from patients with multiple myeloma
Experimental Hematology & Oncology, 2017 Background Multiple myeloma (MM) is a type of hematological malignancy with significant heterogeneity in clinical features and prognosis. Cytogenetic abnormalities are the major factors affecting patient outcomes.
GuoQing Wei +13 more
doaj +1 more source
Regulation of c-maf gene expression by Pax6 in cultured cells [PDF]
Nucleic Acids Research, 2001 c-Maf is a bZip transcription factor expressed in developmental and cellular differentiation processes. Recently, a c-maf knockout mouse model, showing abnormal lens development, has been reported. In order to study the regulation mechanisms of c-maf gene expression during the differentiation process we have cloned and functionally characterized the ...
M, Sakai +5 more
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Immunolocalization of cyclin D1 in the developing lens of c-maf -/- mice [PDF]
Acta Histochemica, 2006 The maf gene encodes a transcription factor protein containing a typical basic/leucine zipper domain structure, a motif for protein dimerization and DNA binding. It has been demonstrated that maf family genes have important roles in embryonic development and cellular differentiation.
Kase, Satoru +8 more
openaire +4 more sources