Results 291 to 300 of about 19,205,329 (382)

Investigating the interaction of ACKR1 and c-Myc in the breast carcinoma tumor microenvironment modulation. [PDF]

Discov Oncol
Talukdar J, Nayek A, Gogoi G, Srivastava TP, Goel I, Sahoo OS, Dhar R, Karmakar S.   +7 more
europepmc   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source

Glutamine signaling specifically activates c-Myc and Mcl-1 to facilitate cancer cell proliferation and survival. [PDF]

Protein Cell
Wang M, Guo FS, Hou DS, Zhang HL, Chen XT, Shen YX, Guo ZF, Zheng ZF, Hu YP, Du PZ, Wang CJ, Lin Y, Yuan YY, Zhao SM, Xu W.   +14 more
europepmc   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

LTBP2 promotes meningioma progression by enhancing glycolysis via the PI3K/AKT/mTOR/c-Myc signaling pathway. [PDF]

Discov Oncol
Li X, Zhang C.
europepmc   +1 more source

Data from c‐Myc, AKT, Hsc70, and the T-Box Transcription Factor TBX3 Form an Important Oncogenic Signaling Axis in Breast Cancer

Stephanie M. Ncube, K.N. ArulJothi, Dirk Lang, Musalula Sinkala, Carly A. Burmeister, Karabo Serala, Jonathan M. Blackburn, Sharon Prince   +7 more
openalex   +1 more source

Widespread microRNA repression by Myc contributes to tumorigenesis

Nature Genetics, 2008
Tsung-Cheng Chang, Duonan Yu, Yun‐Sil Lee, E. Wentzel, D. Arking, K. West, C. Dang, A. Thomas-Tikhonenko, J. Mendell   +8 more
semanticscholar   +1 more source

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

Advanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi, Colby J. Agostino, Jinwei Huang, Toshitha Kannan, Niklas Laenger, Jennifer Londregan, Katlyn Lederer, Michaela Helble, Nicole Bedanova, Cory Livingston, Ebony N. Gary, Madison McCanna, Marta Tarquis Medina, Rumi Habib, Ignacio Rodriguez Relaño, Ivan Maillard, Ami Patel, David Allman, Andrew Kossenkov, Amelia Escolano, Daniel W. Kulp, David. B. Weiner   +21 more
wiley   +1 more source

Targeting c-Myc-p300-CARM1 complex induces ferroptosis and reduces CD8⁺ T cell exhaustion in esophageal squamous cell carcinoma. [PDF]

Int J Biol Sci
Wang Y, Li Y, Ren G, Zhou J, Chen W, Zhang K, Yu X, Yin Y, Cong J, Ma L, Zheng X, Zhao Y, Liu Z.   +12 more
europepmc   +1 more source

Wnt signaling and c-Myc in intestinal epithelium

, 2007
Vanesa Muncan
openalex   +1 more source