Results 341 to 350 of about 19,205,329 (382)

Targeting of IRAK4 and GSPT1 enhances therapeutic efficacy in AML via c-Myc destabilization. [PDF]

Leukemia
Vick EJ, Hassan A, Choi K, Bennett J, Muto T, Clough CA, Culver-Cochran AE, Hueneman K, Bolanos LC, Wunderlich M, Zhang X, McKnight C, Ceribelli M, Holland D, Klumpp-Thomas C, Greis KD, Thomas CJ, Starczynowski DT.   +17 more
europepmc   +1 more source

Targeting MKK3/c-Myc interaction to overcome osimertinib acquired resistance in EGFR mutant lung cancer. [PDF]

Cancer Lett
Chen Z, Vallega KA, Wang D, Bildtsen E, Fu H, Ramalingam SS, Ivanov AA, Sun SY.   +7 more
europepmc   +1 more source

PPDPF promotes the progression of esophageal squamous cell carcinoma via c-Myc/CD24 axis. [PDF]

J Immunother Cancer
Zhu B, Ma N, Liu ZC, Zheng QW, Liang X, Chen Y, Wang YK, Cao HJ, Xia J, Xu S, Qiu XS, Huang JY, Ding K, Xiang YJ, Zhang XR, Qiu L, Chen W, Wang X, Long L, Ni QZ, Li ZG, Yao F, Li JJ.   +22 more
europepmc   +1 more source

Evodiamine Inhibits Colorectal Cancer by Downregulating ASS1 via Wnt/β-Catenin/c-MYC Pathway to Block Arginine Synthesis. [PDF]

Pharmaceuticals (Basel)
Wang H, Deng H, He J, Ma J, Li Y, Lv H, Ran J, Chen D, Li J.   +8 more
europepmc   +1 more source

c-MYC mRNA destabilization inhibited lethal pancreatic cancer <i>in vivo</i> with significant survival outcomes. [PDF]

Front Pharmacol
Dorji JP, Chen Q, Perera SG, Aijaz F, Li P, Sania T, Matsui H, Awah CU.   +7 more
europepmc   +1 more source

The deubiquitination enzyme USP14 promotes the tumourigenesis of gastric cancer by enhancing c-MYC nuclear translocation through deubiquitination of KPNA2. [PDF]

Cell Death Dis
Li J, Tang H, Chang H, Du Y, Du L, Zhao E.   +5 more
europepmc   +1 more source

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C-Myc Staining Method

Definitions, 2020
c-Myc staining is a sensitive immunohistochemical method for studying the tissue localization of c-Myc protein using antibody followed by a microscopic observation of the c-Myc staining distribution.

semanticscholar   +2 more sources

c-Myc-driven Hepatocarcinogenesis

Anticancer Research, 2021
Dysregulation of the c-Myc gene is frequently found in human hepatocellular carcinoma (HCC), often accompanied by genetic and epigenetic alterations in other cancer-related genes. Here, we investigated the tumorigenic potential of c-Myc in diverse genetic environments in which the Ras, Wnt/β-catenin, Sonic hedgehog, or P53 pathways were either ...
Hyuk, Moon, Hyunjung, Park, Simon Weonsang, Ro   +2 more
openaire   +2 more sources

C-Myc Translocation

Definitions, 2020

semanticscholar   +2 more sources

Recent Update on Targeting c-MYC G-Quadruplexes by Small Molecules for Anticancer Therapeutics.

Journal of Medicinal Chemistry, 2020
Guanine-rich DNA sequences have the propensity to adopt four-stranded tetrahelical G-quadruplex (G4) structures that are overrepresented in gene promoters. The structural polymorphism and physicochemical properties of these non-Watson-Crick G4 structures
Ritapa Chaudhuri, S. Bhattacharya, J. Dash, S. Bhattacharya   +3 more
semanticscholar   +1 more source