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C-Reactive Protein (CRP)-Lowering Agents [PDF]

open access: yesCardiovascular Drug Reviews, 2006
ABSTRACTC‐reactive protein (CRP) plays a role in the pathogenesis of cardiovascular disease. It is a marker and predictor of cardiovascular disease. CRP possesses numerous cardiovascular effects (clotting, generation of oxygen radicals, increase in the expression of adhesion molecules and plasminogen activator inhibitor‐1, plaque destabilization) that ...
Kailash Prasad
exaly   +3 more sources
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C‐Reactive Protein (Crp) as a Marker for Infection

Acta Obstetricia et Gynecologica Scandinavica, 1988
(1988). C-Reactive Protein (Crp) as a Marker for Infection. Acta Obstetricia et Gynecologica Scandinavica: Vol. 67, No. 2, pp. 189-189.
N M, Fisk, J W, Fysh
openaire   +2 more sources

C-reactive protein (CRP) of the syrian hamster

Biochemistry, 1991
Complementary and genomic clones encoding the mRNA and gene for a protein in the Syrian hamster that is highly homologous to C-reactive protein (CRP) have been isolated and studied. Coding sequence of the genomic clone is identical with that of the cDNA clone and predicts a mature protein of 206 amino acids and a 19 amino acid signal peptide.
S B, Dowton, S N, Holden
openaire   +2 more sources

Association of C-reactive protein (CRP) gene allelic variants with serum CRP levels and hypertension in Turkish adults

open access: yesAtherosclerosis, 2009
Objective: Serum C-reactive protein (CRP) is an independent risk factor for cardiovascular disease and metabolic syndrome (MetS). The aim of this study was to analyze the CRP gene allelic variations in the Turkish adult risk factor (TARF) study and ...
Terho Lehtimäki   +1 more
exaly   +2 more sources

C-reactive protein (CRP) in cerebro-vascular events

Atherosclerosis, 1999
C-reactive protein (CRP) is a useful prognostic factor in coronary heart disease. It has not been previously studied in acute cerebro-vascular events, which was the topic of the present study.Patients admitted to the hospital for an acute cerebro-vascular event were prospectively investigated.
C R, Canova, C, Courtin, W H, Reinhart
openaire   +2 more sources

Biosensors; noninvasive method in detection of C-reactive protein (CRP)

Biomedical Microdevices, 2023
Early diagnosis of C reactive protein (CRP) is critical to applying effective therapies for related diseases. Diagnostic technology in today's healthcare systems is mostly deployed in central laboratories, involves expensive and time-consuming processes, and is operated by specialized personnel. For example, the enzyme-linked immunosorbent assay (ELISA)
Hamidreza Hassanzadeh, Khanmiri   +5 more
openaire   +2 more sources

Impact of C-reactive Protein (CRP) on Surfactant Function

The Journal of Trauma: Injury, Infection, and Critical Care, 1989
Plasma levels of the acute-phase reactant, C-reactive protein (CRP), increase up to one thousand-fold as a result of trauma or inflammation. CRP binds to phosphorylcholine (PC) in a calcium-ion dependent manner. The structural homology between PC and the major phospholipid component of surfactant, dipalmitoyl phosphatidylcholine (DPPC), led to the ...
J J, Li   +6 more
openaire   +2 more sources

Perplexity of monocyte responses to C-reactive protein (CRP)

Thrombosis and Haemostasis, 2008
Thromb Haemost 2008; 99: 461–462 C-reactive protein (CRP), a member of the pentraxin family, is one of the prototypic plasma biomarkers of inflammation (1, 2). The physiological roles of CRP in the innate immune response have, however, remained elusive as it possesses both proand anti-inflammatory actions (1, 2).
openaire   +2 more sources

Characteristics of the binding of human C‐reactive protein (CRP) to laminin

Journal of Cellular Biochemistry, 1989
AbstractHuman CRP binds to the basement membrane protein laminin in vitro in a Ca2+‐dependent manner via the phosphorylcholine (PC) binding site of C‐reactive protein (CRP). The binding was saturable at a molar ratio of 4 (CRP/laminin). The specificity of the binding was shown by inhibition of binding of labeled CRP to laminin by unlabeled CRP, but not
S J, Swanson   +2 more
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Development of monkey C-reactive protein (CRP) assay methods

Veterinary Immunology and Immunopathology, 1998
Monkey-specific C-reactive protein (CRP) assay methods (enzyme-linked immunosorbent assay (ELISA) and turbidimetric immunoassay (TIA)) were developed. The anti-monkey CRP serum was prepared by immunization of rabbits with the immune complex formed between the acute-phase serum from turpentine oil-inoculated monkeys and goat anti-human CRP serum.
T, Jinbo   +6 more
openaire   +2 more sources

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