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Evolution of C-Reactive Protein [PDF]

Frontiers in Immunology, 2019
C-reactive protein (CRP) is an evolutionarily conserved protein. From arthropods to humans, CRP has been found in every organism where the presence of CRP has been sought.
Asmita Pathak, Alok Agrawal
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C-Reactive Protein and Arteriosclerosis

Mediators of Inflammation, 2014
Although extensively studied and indeed emotionally discussed for more than two decades the role of C-reactive protein (CRP) in cardiovascular disease remains controversial. Three major questions are still not yet resolved. (1) Is CRP a clinically relevant marker of cardiovascular risk? (2) Is CRP even more than a risk marker, that is, a risk factor in
Jan Torzewski, Jianglin Fan, Heribert Schunkert, Alexander Szalai, Michael Torzewski   +4 more
doaj   +3 more sources

C-Reactive Protein in Atherothrombosis and Angiogenesis [PDF]

Frontiers in Immunology, 2018
C-reactive protein (CRP) is a short pentraxin mainly found as a pentamer in the circulation, or as non-soluble monomers CRP (mCRP) in tissues, exerting different functions.
Lina Badimon, Lina Badimon, Esther Peña, Esther Peña, Gemma Arderiu, Teresa Padró, Teresa Padró, Mark Slevin, Gemma Vilahur, Gemma Vilahur, Gemma Chiva-Blanch   +10 more
doaj   +5 more sources

C-reactive Protein [PDF]

Journal of Biological Chemistry, 2004
C-reactive protein (CRP) is a phylogenetically highly conserved plasma protein, with homologs in vertebrates and many invertebrates, that participates in the systemic response to inflammation. Its plasma concentration increases during inflammatory states, a characteristic that has long been employed for clinical purposes.
Steven, Black, Irving, Kushner, David, Samols   +2 more
openaire   +5 more sources

Dependence of C-Reactive Protein & Cholesterol [PDF]

Kirkuk Journal of Science, 2011
This study had been designed to illustrate the relationship between immunological and biochemical abnormalities in patients with coronary heart disease (CHD) in Dohuk. These patients were referred to the general Azadi hospital in Dohuk for investigation.
Malika K. Najeeb Al Barwari, Ahmed S. Mirza Al- Barwari   +1 more
doaj   +1 more source

Therapeutic Lowering of C-Reactive Protein

Frontiers in Immunology, 2021
In the blood of healthy individuals C-reactive protein (CRP) is typically quite scarce, whereas its blood concentration can rise robustly and rapidly in response to tissue damage and inflammation associated with trauma and infectious and non-infectious ...
Rachel V. Jimenez, Alexander J. Szalai
doaj   +1 more source

C‐reactive protein and ageing [PDF]

Clinical and Experimental Pharmacology and Physiology, 2017
SummaryIncreasing evidence shows that C‐reactive protein (CRP) is not only an inflammatory biomarker but also an important risk factor associated with ageing‐related diseases including cardiovascular disease, hypertension, diabetes mellitus, and kidney disease.
Ying Tang, Erik Fung, Anping Xu, Hui‐Yao Lan   +3 more
openaire   +2 more sources

Deficiency of C-reactive protein or human C-reactive protein transgenic treatment aggravates influenza A infection in mice

Frontiers in Immunology, 2022
C-reactive protein (CRP) has been shown to be a potential candidate target in the immunotherapy of severe influenza A infection. However, it is unclear on the pathogenesis associated with CRP in influenza infections.
Zhuohan Zhang, Zhuohan Zhang, Yongjun Gao, Yongjun Gao, Li Li, Li Li, Junhao Luo, Junhao Luo, Rongbao Gao, Rongbao Gao   +9 more
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Role of C-Reactive Protein at Sites of Inflammation and Infection

Frontiers in Immunology, 2018
C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at sites of infection or inflammation. CRP is produced as a homopentameric protein, termed native CRP (nCRP), which can irreversibly dissociate at sites of ...
Nicola R. Sproston, Jason J. Ashworth
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Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai

National Journal of Physiology, Pharmacy and Pharmacology, 2023
Background: The incidence and prevalence of hypertension have been increasing steadily in the present era. Inflammation is a proven key factor in the pathogenesis of hypertension.
Hemalatha P, Prince Johnson Samuel
doaj   +1 more source