An ELISA Assay for Quantifying Monomeric C-Reactive Protein in Plasma [PDF]
Frontiers in Immunology, 2018 Native C-reactive protein (nCRP) is a non-specific marker of inflammation being claimed as a bystander in several chronic disorders. Accumulating evidence indicates that nCRP dissociates to and acts primarily as the monomeric conformation (mCRP) at ...
Lin Zhang +6 more
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Higher monomeric C-reactive protein levels are associated with premature coronary artery disease [PDF]
Frontiers in ImmunologyIntroductionChronic inflammation is a major risk factor for coronary artery disease (CAD). Currently, the inflammatory cardiovascular risk is assessed via C-reactive protein (CRP) levels measured using a high-sensitivity assay (hsCRP).
Ivan Melnikov +14 more
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Monomeric C-reactive protein is associated with severity and prognosis of decompensated hepatitis B cirrhosis [PDF]
Frontiers in ImmunologyC-reactive protein (CRP) is an acute-phase protein produced by the liver in response to infection and during chronic inflammatory disorders. Systemic inflammation is a major driver of cirrhosis progression from the compensated to the decompensated stage.
Ning Gao +15 more
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Monomeric C-reactive protein as a biomarker for major depressive disorder [PDF]
Frontiers in Psychiatry, 2023 Neuroinflammation has been postulated to be a key factor in the pathogenesis of major depressive disorder (MDD). With this is mind, there has been a wave of research looking into pro-inflammatory mediators as potential biomarkers for MDD.
Mary G. Hornick, Lawrence A. Potempa
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Monomeric C‐reactive protein induces the cellular pathology of Alzheimer's disease [PDF]
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022 Introduction Human study shows that elevated C‐reactive protein (CRP) in blood impacts apolipoprotein E (APOE) ε4, but not APOE ε3 or APOE ε2, genotype to increase the risk of Alzheimer's disease (AD).
Qini Gan +8 more
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Monomeric C-Reactive Protein: Current Perspectives for Utilization and Inclusion as a Prognostic Indicator and Therapeutic Target [PDF]
Frontiers in Immunology, 2022 Monomeric C-reactive protein (mCRP), once thought to be a figment of the imagination and whose biological activity was ascribed to its sodium azide preservative, has now pronounced itself as a critical molecule playing a direct role in mediating many of ...
Mark Slevin +5 more
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Monomeric C-Reactive Protein and Cerebral Hemorrhage: From Bench to Bedside [PDF]
Frontiers in Immunology, 2018 C-reactive protein (CRP) is an important mediator and a hallmark of the acute-phase response to inflammation. High-sensitivity assays that accurately measure levels of CRP have been recommended for use in risk assessment in ischemic stroke patients ...
Mario Di Napoli +7 more
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Monomeric C-Reactive Protein in Serum With Markedly Elevated CRP Levels Shares Common Calcium-Dependent Ligand Binding Properties With an in vitro Dissociated Form of C-Reactive Protein [PDF]
Frontiers in Immunology, 2020 A monomeric form of C-reactive protein (CRP) which precipitates with cell wall pneumococcal C polysaccharide (CWPS) and retains the ability to reversibly bind to its ligand phosphocholine has been produced through urea-induced dissociation at an ...
Robert D. Williams +6 more
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Antibody Protection against Long-Term Memory Loss Induced by Monomeric C-Reactive Protein in a Mouse Model of Dementia [PDF]
Biomedicines, 2021 Monomeric C-reactive protein (mCRP), the activated isoform of CRP, induces tissue damage in a range of inflammatory pathologies. Its detection in infarcted human brain tissue and its experimentally proven ability to promote dementia with Alzheimer’s ...
Elisa García-Lara +12 more
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Serum p-Glycoprotein and Monomeric C-Reactive Protein are Elevated in Takayasu Arteritis [PDF]
Journal of Inflammation ResearchDarpan Radheshyam Thakare,1,2,* Kritika Singh,1,* Tooba Qamar,1 Deeksha Singh,1 Sandeep Balakrishnan,1 Upendra Rathore,1 Neeraj Jain,3 Manish Ora,4 Durga Prasanna Misra1 1Department of Clinical Immunology and Rheumatology, Sanjay Gandhi ...
Thakare DR +8 more
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