Corrigendum: Monomeric C-Reactive Protein Binds and Neutralizes Receptor Activator of NF-κB Ligand-Induced Osteoclast Differentiation [PDF]
Frontiers in Immunology, 2020 Zhe-Kun Jia +6 more
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Monomeric C-Reactive Protein - A Feature of Inflammatory Disease Associated With Cardiovascular Pathophysiological Complications? [PDF]
In Vivo, 2021 Monomeric C-reactive protein (mCRP), the dissociated form of native C-reactive protein, is a critical molecule that causes and perpetuates inflammation in serious diseases. It has 'adhesive'-like properties causing aggregation of blood cells and platelets, and can stick permanently within arterial tissue where it can contribute to further complications
Zeinolabediny Y, Kumar S, Slevin M.
europepmc +4 more sources
Monomeric C-reactive protein and inflammatory injury in myocardial infarction. [PDF]
Cardiovasc Res, 2012 This editorial refers to ‘Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction’ by J. Habersberger et al. , pp. 64–72, this issue. C-reactive protein, a member of the pentraxin superfamily, is a prototypical ‘acute-phase’ protein that is synthesized at a low rate under physiological ...
Frangogiannis NG.
europepmc +4 more sources
Monomeric C-reactive Protein as a Mediator of Chronic Inflammation in Obesity. [PDF]
CureusPentek A, Bacârea A.
europepmc +2 more sources
Monomeric C-reactive protein and inflammation in age-related macular degeneration. [PDF]
J Pathol, 2016 AbstractAge‐related macular degeneration (AMD) is a devastating disease characterized by central vision loss in elderly individuals. Previous studies have suggested a link between elevated levels of total C‐reactive protein (CRP) in the choroid, CFH genotype, and AMD status; however, the structural form of CRP present in the choroid, its relationship ...
Chirco KR +7 more
europepmc +4 more sources
Different effects of oral and transdermal hormone replacement therapies on Factor IX, APC resistance, t-PA, PAI and C- reactive protein - a cross-sectional population survey [PDF]
, 2001 The effects of hormone replacement therapy (HRT) on thrombosis risk, thrombotic variables, and the inflammatory marker C- reactive protein (CRP) may vary by route of administration (oral versus transdermal).
Lowe, G.D.O. +5 more
core +8 more sources
An Intrinsically Disordered Motif Mediates Diverse Actions of Monomeric C-reactive Protein. [PDF]
J Biol Chem, 2016 Most proinflammatory actions of C-reactive protein (CRP) are only expressed following dissociation of its native pentameric assembly into monomeric form (mCRP). However, little is known about what underlies the greatly enhanced activities of mCRP. Here we show that a single sequence motif, i.e. cholesterol binding sequence (CBS; a.a.
Li HY +11 more
europepmc +4 more sources
Hypothesis : soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease [PDF]
, 2010 Considerable evidence points to oxidative stress in the brain as an important event in the early stages of Alzheimer's disease (AD). The transition metal ions of Cu, Fe, and Zn are all enriched in the amyloid cores of senile plaques in AD.
Tabner, Brian J +2 more
core +5 more sources
C-Reactive Protein and Cancer—Diagnostic and Therapeutic Insights
Frontiers in Immunology, 2020 Cancer disease describes any pathology involving uncontrolled cell growth. As cells duplicate, they can remain localized in defined tissues, forming tumor masses and altering their microenvironmental niche, or they can disseminate throughout the body in ...
Peter C. Hart +3 more
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Role of C-Reactive Protein at Sites of Inflammation and Infection
Frontiers in Immunology, 2018 C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at sites of infection or inflammation. CRP is produced as a homopentameric protein, termed native CRP (nCRP), which can irreversibly dissociate at sites of ...
Nicola R. Sproston, Jason J. Ashworth
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