Results 31 to 40 of about 23,062,194 (220)

Corrigendum: The cholesterol-binding sequence in monomeric C-reactive protein binds to the SARS-CoV-2 spike receptor-binding domain and blocks interaction with Angiotensin-converting enzyme 2 [PDF]

Frontiers in Immunology, 2022
Hai-yun Li, Hai-yun Li, Ning Gao, Cheng-yang Liu, Xiao-ling Liu, Feng Wu, Nini Dai, Jing Han, Jing Han, Qiu-yu Li   +9 more
doaj   +2 more sources

Monomeric C-reactive Protein as a Mediator of Chronic Inflammation in Obesity. [PDF]

Cureus
Obesity is associated with persistent low-grade inflammation. This inflammation results from interactions between adipose tissue, immune cells, and metabolic pathways. High-sensitivity C-reactive protein (CRP) serves as a marker for systemic inflammation but does not evaluate local inflammatory processes.
Pentek A, Bacârea A.
europepmc   +3 more sources

Circulating Levels of the Proinflammatory Monomeric Isoform of C-Reactive Protein (mCRP) Correlate with Intra-Tumoral mCRP Abundance in Stage II-III Colon Cancer Patients

Journal of Inflammation Research
Anniken Jørlo Fuglestad,1– 3 Paula Anna Bousquet,1 Anne Helene Køstner,3 Sebastian Meltzer,1 Britta Kleist,4 Anne Hansen Ree,1,2 Ibraheem M Rajab,5 Lawrence A Potempa,6 Rafael Fernandez-Botran,7 Christian Kersten1,3 1Department of Oncology, Akershus ...
Fuglestad AJ, Bousquet PA, Køstner AH, Meltzer S, Kleist B, Ree AH, Rajab IM, Potempa LA, Fernandez-Botran R, Kersten C   +9 more
doaj   +2 more sources

Corrigendum: Monomeric C-Reactive Protein Binds and Neutralizes Receptor Activator of NF-κB Ligand-Induced Osteoclast Differentiation [PDF]

Frontiers in Immunology, 2020
Zhe-Kun Jia, Hai-Yun Li, Yu-Lin Liang, Lawrence A. Potempa, Shang-Rong Ji, Yi Wu, Yi Wu   +6 more
doaj   +2 more sources

Immunoradiometric assay of circulating C-reactive protein: age-related values in the adult general population [PDF]

, 2000
Background: Increased values of C-reactive protein (CRP), the classical acute phase protein, within the range below 5 mg/L, previously considered to be within the reference interval, are strongly associated with increased risk of atherothrombotic events,
Hutchinson, W.L., Lowe, G.D.O., Koenig, W., Frohlich, M., Sund, M., Pepys, M.B.   +5 more
core   +7 more sources

Monomeric C-Reactive Protein - A Feature of Inflammatory Disease Associated With Cardiovascular Pathophysiological Complications? [PDF]

In Vivo, 2021
Monomeric C-reactive protein (mCRP), the dissociated form of native C-reactive protein, is a critical molecule that causes and perpetuates inflammation in serious diseases. It has 'adhesive'-like properties causing aggregation of blood cells and platelets, and can stick permanently within arterial tissue where it can contribute to further complications
Zeinolabediny Y, Kumar S, Slevin M.
europepmc   +4 more sources

Monomeric C-reactive protein and inflammatory injury in myocardial infarction. [PDF]

Cardiovasc Res, 2012
This editorial refers to ‘Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction’ by J. Habersberger et al. , pp. 64–72, this issue. C-reactive protein, a member of the pentraxin superfamily, is a prototypical ‘acute-phase’ protein that is synthesized at a low rate under physiological ...
Frangogiannis NG.
europepmc   +4 more sources

Microglial pro-inflammatory mechanisms induced by monomeric C-reactive protein are counteracted by soluble epoxide hydrolase inhibitors. [PDF]

Int Immunopharmacol
Bartra C, Vuraić K, Yuan Y, Codony S, Valdés-Quiroz H, Casal C, Slevin M, Máquez-Kisinousky L, Planas AM, Griñán-Ferré C, Pallàs M, Morisseau C, Hammock BD, Vázquez S, Suñol C, Sanfeliu C.   +15 more
europepmc   +2 more sources

Monomeric C-reactive protein and inflammation in age-related macular degeneration. [PDF]

J Pathol, 2016
AbstractAge‐related macular degeneration (AMD) is a devastating disease characterized by central vision loss in elderly individuals. Previous studies have suggested a link between elevated levels of total C‐reactive protein (CRP) in the choroid, CFH genotype, and AMD status; however, the structural form of CRP present in the choroid, its relationship ...
Chirco KR, Whitmore SS, Wang K, Potempa LA, Halder JA, Stone EM, Tucker BA, Mullins RF.   +7 more
europepmc   +4 more sources

An Intrinsically Disordered Motif Mediates Diverse Actions of Monomeric C-reactive Protein. [PDF]

J Biol Chem, 2016
Most proinflammatory actions of C-reactive protein (CRP) are only expressed following dissociation of its native pentameric assembly into monomeric form (mCRP). However, little is known about what underlies the greatly enhanced activities of mCRP. Here we show that a single sequence motif, i.e. cholesterol binding sequence (CBS; a.a.
Li HY, Wang J, Meng F, Jia ZK, Su Y, Bai QF, Lv LL, Ma FR, Potempa LA, Yan YB, Ji SR, Wu Y.   +11 more
europepmc   +4 more sources