Antibody Protection against Long-Term Memory Loss Induced by Monomeric C-Reactive Protein in a Mouse Model of Dementia [PDF]
Biomedicines, 2021 Monomeric C-reactive protein (mCRP), the activated isoform of CRP, induces tissue damage in a range of inflammatory pathologies. Its detection in infarcted human brain tissue and its experimentally proven ability to promote dementia with Alzheimer’s ...
Elisa García-Lara +12 more
doaj +4 more sources
Serum p-Glycoprotein and Monomeric C-Reactive Protein are Elevated in Takayasu Arteritis [PDF]
Journal of Inflammation ResearchDarpan Radheshyam Thakare,1,2,* Kritika Singh,1,* Tooba Qamar,1 Deeksha Singh,1 Sandeep Balakrishnan,1 Upendra Rathore,1 Neeraj Jain,3 Manish Ora,4 Durga Prasanna Misra1 1Department of Clinical Immunology and Rheumatology, Sanjay Gandhi ...
Thakare DR +8 more
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Monomeric C-reactive protein: a link between chronic inflammation and neurodegeneration? [PDF]
Neural Regeneration Research, 2023 Nicoleta Arnaut +2 more
doaj +5 more sources
Monomeric C-reactive protein as a therapeutic target in inflammatory diseases [PDF]
RMD OpenChitose Fujita +3 more
doaj +5 more sources
Hydroxycholesterol binds and enhances the anti-viral activities of zebrafish monomeric c-reactive protein isoforms. [PDF]
PLoS ONE, 2019 C-reactive proteins (CRPs) are among the faster acute-phase inflammation-responses proteins encoded by one gene (hcrp) in humans and seven genes (crp1-7) in zebrafish (Danio rerio) with importance in bacterial and viral infections.
Melissa Bello-Perez +4 more
doaj +6 more sources
High prevalence of autoantibodies against monomeric C reactive protein (CRP) in children with PFAPA syndrome [PDF]
Journal of Medical Biochemistry, 2018 PFAPA (periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis) syndrome is an autoinflammatory disorder of unknown etiology. The aim of our study was to evaluate whether the presence of anti-mCRP autoantibodies (anti-mCRP) might possibly ...
Kraszewska-Glomba Barbara +3 more
doaj +5 more sources
Monomeric C-reactive protein level is associated with osteoarthritis. [PDF]
Exp Ther Med, 2022 Osteoarthritis (OA) is a chronic joint disease characterized by articular cartilage degeneration and secondary bone hyperplasia. C-reactive protein (CRP) is an acute-phase protein that is widely used as a marker of inflammation. Elevated plasma levels of CRP are commonly observed in patients with OA during the acute phase.
Liang Y +6 more
europepmc +4 more sources
Monomeric C-Reactive Protein - A Feature of Inflammatory Disease Associated With Cardiovascular Pathophysiological Complications? [PDF]
In Vivo, 2021 Monomeric C-reactive protein (mCRP), the dissociated form of native C-reactive protein, is a critical molecule that causes and perpetuates inflammation in serious diseases. It has 'adhesive'-like properties causing aggregation of blood cells and platelets, and can stick permanently within arterial tissue where it can contribute to further complications
Zeinolabediny Y, Kumar S, Slevin M.
europepmc +4 more sources
The Cholesterol-Binding Sequence in Monomeric C-Reactive Protein Binds to the SARS-CoV-2 Spike Receptor-Binding Domain and Blocks Interaction With Angiotensin-Converting Enzyme 2 [PDF]
Frontiers in Immunology, 2022 The receptor-binding domain (RBD) of the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the human angiotensin-converting enzyme 2 (ACE2) receptor, which is a prerequisite for the virus to enter the cell. C-reactive
Hai-yun Li +9 more
doaj +2 more sources
The monomeric C-reactive protein level is associated with the increase in carotid plaque number in patients with subclinical carotid atherosclerosis [PDF]
Frontiers in Cardiovascular Medicine, 2022 The high-sensitivity C-reactive protein (hsCRP) assay measures the level of the pentameric form of CRP in blood. Currently, there are no available assays measuring the level of the monomeric form of CRP (mCRP), produced at sites of local inflammation. We
Ivan Melnikov +15 more
doaj +2 more sources