Results 51 to 60 of about 23,062,194 (220)

Serum CRP interacts with SPARC and regulate immune response in severe cases of COVID-19 infection

Frontiers in Immunology, 2023
Serum C-reactive protein (CRP) has been found elevated during COVID-19 infection, and associated with systematic inflammation as well as a poor clinical outcome.
Chengyang Liu, Chenyang Zheng, Xipeng Shen, Ling Liang, Qiuyu Li   +4 more
doaj   +1 more source

C-reactive protein: a target for therapy to reduce inflammation

Frontiers in Immunology, 2023
C-reactive protein (CRP) is well-recognized as a sensitive biomarker of inflammation. Association of elevations in plasma/serum CRP level with disease state has received considerable attention, even though CRP is not a specific indicator of a single ...
Salma A. Rizo-Téllez, Salma A. Rizo-Téllez, Meriem Sekheri, Meriem Sekheri, János G. Filep, János G. Filep   +5 more
doaj   +1 more source

Additional file 3 of Associations of C-reactive protein isoforms with systemic lupus erythematosus phenotypes and disease activity

, 2022
Additional file 3: Supplementary Figure 3. Standard curves and reactivity of the monoclonal detection antibody 8C10 towards monomeric C-reactive protein (mCRP) and pentameric (p)CRP: (A) standard curve for 8C10 antibody with mCRP; (B) reactivity of 8C10 ...
Jesper Karlsson (12863105), Jonas Wetterö (2432866), Johan Rönnelid (54462), Maria Weiner (12863108), Rafael Fernandez-Botran (3531761), Christopher Sjöwall (3374)   +5 more
core   +1 more source

C-reactive protein: associations with haematological variables, cardiovascular risk factors and prevalent cardiovascular disease [PDF]

, 2003
C-reactive protein (CRP) has been proposed as a risk factor for cardiovascular disease; however, this association is confounded by mutual relationships with both classical and haematological cardiovascular risk factors. We, therefore, measured CRP with a
Lowe, G.D.O., Rumley, A., Tunstall-Pedoe, H., Woodward, M.   +3 more
core   +1 more source

CRP Is Transported by Monocytes and Monocyte-Derived Exosomes in the Blood of Patients with Coronary Artery Disease

Biomedicines, 2020
The objective of this work was to study the ability of blood cells and their microparticles to transport monomeric and pentameric forms of C-reactive protein (mCRP and pCRP) in the blood of patients with coronary artery disease (CAD).
Ivan Melnikov, Sergey Kozlov, Olga Saburova, Ekaterina Zubkova, Olga Guseva, Sergey Domogatsky, Tatiana Arefieva, Natalia Radyukhina, Maria Zvereva, Yuliya Avtaeva, Lyudmila Buryachkovskaya, Zufar Gabbasov   +11 more
doaj   +1 more source

Topological localization of monomeric C-reactive protein determines proinflammatory endothelial cell responses. [PDF]

J Biol Chem, 2014
The activation of endothelial cells (ECs) by monomeric C-reactive protein (mCRP) has been implicated in contributing to atherogenesis. However, the potent proinflammatory actions of mCRP on ECs in vitro appear to be incompatible with the atheroprotective effects of mCRP in a mouse model.
Li HY, Wang J, Wu YX, Zhang L, Liu ZP, Filep JG, Potempa LA, Wu Y, Ji SR.   +8 more
europepmc   +4 more sources

C-reactive protein haplotypes and dispositional optimism in obese and nonobese elderly subjects [PDF]

, 2011
Background Chronic low-grade inflammation, characterized by elevated plasma levels of C-reactive protein (CRP), has been inversely associated with dispositional optimism.
Craen, A.J.M., Westendorp, R.G., P. Eline Slagboom, Anton J. M. de Craen, Kromhout, D., Johanna M. Geleijnse, Craen, A.J.M. de, Erik J. Giltay, Rius-Ottenheim, N., Rudi G. Westendorp, Geleijnse, J.M., Giltay, E.J., Slagboom, P.E., Mast, R.C. van der, Nathaly Rius-Ottenheim, Daan Kromhout, Frans G. Zitman, Roos C. van der Mast, Zitman, F.G., Rius Ottenheim, N.   +19 more
core   +1 more source

Monomeric C-Reactive Protein Decreases Acetylated LDL Uptake in Human Endothelial Cells [PDF]

Clinical Chemistry, 2009
AbstractBackground: C-reactive protein (CRP) is a risk marker for cardiovascular disease and has been implicated in atherogenesis. In atherosclerotic plaques, it colocalizes with oxidized LDL (oxLDL) and promotes oxLDL uptake by macrophages, suggesting an important cross-talk between CRP and lipid processing.
Susanne B, Schwedler, Thomas, Hansen-Hagge, Matthias, Reichert, Daniel, Schmiedeke, Reinhard, Schneider, Jan, Galle, Lawrence A, Potempa, Christoph, Wanner, János G, Filep   +8 more
openaire   +2 more sources

The Multiple Faces of C-Reactive Protein—Physiological and Pathophysiological Implications in Cardiovascular Disease

Molecules, 2019
C-reactive protein (CRP) is an intriguing protein which plays a variety of roles in either physiological or pathophysiological states. For years it has been regarded merely as a useful biomarker of infection, tissue injury and inflammation, and it was ...
Magdalena Boncler, Yi Wu, Cezary Watala
doaj   +1 more source

Functional activities of C-reactive protein on neutrophils [PDF]

C-reactive protein (CRP) is a member of the pentraxin family which opsonises S. pneumoniae through its binding to phosphorylcholine. In addition, CRP binds to Fcγ receptors: FcγRI with high affinity and, probably, FcγRIIA with lower affinity.
Rodriguez, Jairo Antonio
core   +1 more source