Results 201 to 210 of about 44,074,051 (232)

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

C-S-H gel dissolution kinetics

open access: yes, 2020
Trapote-Barreira, Ana   +2 more
openaire   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The Fracture of C-S-H and C-S-H/CH Mixtures

Cement and Concrete Research, 1998
Abstract The fracture behavior of six well-characterized synthetic preparations of C-S-H and C-S-H/CH mixtures was investigated. The C/S ratios of the C-S-H ranged from 0.68 to 1.49. Log crack velocity vs. stress intensity (log V vs. K I ) curves were obtained for compacted double-torsion specimens prepared with a wide range of porosity values ...
Beaudoin, J. J., Gu, P., Myers, R. E.
openaire   +2 more sources

The nanogranular nature of C–S–H

Journal of the Mechanics and Physics of Solids, 2007
Abstract Despite its ubiquitous presence as binding phase in all cementitious materials, the mechanical behavior of calcium–silicate–hydrates (C–S–H) is still an enigma that has deceived many decoding attempts from experimental and theoretical sides. In this paper, we propose and validate a new technique and experimental protocol to rationally assess
Constantinides, Georgios   +1 more
openaire   +3 more sources

Rietveld refinement of the structures of 1.0 C-S-H and 1.5 C-S-H

Cement and Concrete Research, 2012
Low-Q region Rietveld analyses were performed on C-S-H synchrotron XRD patterns, using the software MAUD. Two different crystal structures of tobermorite 11 A were used as a starting model: monoclinic ordered Merlino tobermorite, and orthorhombic disordered Hamid tobermorite.
Battocchio, Francesco   +2 more
openaire   +2 more sources

Multiscale Modeling of the Dielectric Response of C-S-H

2023
The interpretation of dielectric measurements in cement-based materials, as well as multiscale modeling strategies, requires the knowledge of the intrinsic permittivity of their various constituent phases. Calcium silicate hydrates (C-S-H) is the major hydrated phase in concrete (when clinker is the main cement compound), but to date, its frequency ...
Hamadouche, Sofiane Ait   +5 more
openaire   +3 more sources

On the formation of cementitious C–S–H nanoparticles

Journal of Computer-Aided Materials Design, 2007
Peer ...
Manzano, Hegoi   +2 more
openaire   +2 more sources

Hydration Kinetics and Gel Morphology of C-S-H

CONCREEP 10, 2015
Calcium-silicate hydrate (C-S-H) is the main binder in cement and concrete. It starts forming from the early stages of cement hydration and it progressively densifies as cement sets. C-S-H nanoscale building blocks form a cohesive gel, whose structure and mechanics are still poorly understood, in spite of its practical importance.
Ioannidou, K.   +4 more
openaire   +4 more sources

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