Results 61 to 70 of about 45,573,897 (286)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

New insight into the craftsmanship of sucrose-modified rammed earth-lime materials

open access: yesJournal of Asian Architecture and Building Engineering, 2022
In this work, the performance and mechanism of a Chinese traditional sucrose-modified rammed earth-lime were discussed in lab for its potential utilization in the restoration of rammed earth-lime architectural heritages.
Shiqiang Fang   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Probing the time-dependent behavior of calcium-silicate-hydrate gel by nanoindentation continuous stiffness measurement

open access: yesDevelopments in the Built Environment
Calcium-silicate-hydrate (C–S–H) is the most important phase in concrete materials, and plays a dominant role in the time-dependent properties of concrete.
Gaoyan Liu, Shun Yao, Chuanlin Hu
doaj   +1 more source

Hydration and Microstructure of Steel Slag as Cementitious Material and Fine Aggregate in Mortar

open access: yesMolecules, 2020
Due to the low hydration activity and poor volume stability, extensive steel slag utilization is restricted. In this paper, the hydration process and microstructure of alkali-activated materials with steel slag as a cementitious material and fine ...
Wu Jing   +3 more
doaj   +1 more source

Study on preparation and properties of composite fire prevention gel for mine

open access: yesMeikuang Anquan, 2022
In view of the problems of hydration cracking and powdering, uncontrollable gelation time and poor compressive strength of sodium silicate gel, poor fluidity, small penetration range and high cost of organic gel, combined with the characteristics of ...
LIU Jie   +6 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Stray Current Affects the Release of Bound Chloride Ions in Hydrated Cement Paste

open access: yesInternational Journal of Electrochemical Science, 2018
Here, the effect of stray current on the release of bound chloride ions was evaluated using applied direct current (DC). Stray current induced the release of bound chloride ions, which escalated with both increasing loading time and voltage.
Chonggen Pan, Jian Geng, Qingjun Ding
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Property investigation of calcium-silicate-hydrate (C-S-H) gel in cementitious composites

open access: yes, 2014
Calcium-silicate-hydrate (C-S-H) gel, the main product of cement hydration, contributes the most to engineering properties of concrete. Hence, the microstructural physical and mechanical properties of C-S-H gel present in cementitious composites were ...
Hu, Chuanlin   +4 more
core   +1 more source

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