Results 201 to 210 of about 66,518 (227)

Cardiometabolic‐Inflammatory Risk Factors and Cognitive Decline Among Older Indians—Report From a Nationally Representative, Longitudinal Study

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Rapid increase in cardiometabolic diseases in India may contribute to increased incidence of late‐life cognitive impairment. This study focuses on associations between baseline cardiometabolic risk factors and subsequent decline in cognitive function among older adults in India, leveraging data from two waves (Wave 1: 2017–2020 ...
Joyita Banerjee, Jung Ki Kim, Emma Nichols, Pranali Khobragade, A. B. Dey, Sharmistha Dey, Eileen Crimmins, David Flood, Kenneth M. Langa, Jinkook Lee, Peifeng Hu   +10 more
wiley   +1 more source

Phytosulfokine signalling blocks mycotoxin toxicity in Arabidopsis and mediates suppression of cell death activated by bacterial microbe‐associated molecular patterns

New Phytologist, EarlyView.
Summary Fumonisin B1 (FB1) is a mycotoxin that disrupts ceramide biosynthesis and kills plants. Prior activation with bacterial microbe‐associated molecular patterns (MAMPs), such as components of bacterial flagella, effectively suppresses FB1‐induced cell death.
Ali O. Alqarni, John M. U. Hamilton, Adrian P. Brown, Stephen Chivasa   +3 more
wiley   +1 more source

Cardiomyocyte-derived C-type natriuretic peptide diminishes myocardial ischaemic injury by promoting revascularisation and limiting fibrotic burden

Vanessa J. Lowe, Aisah A. Aubdool, Amie J. Moyes, Joshua P. Dignam, Cristina Pérez‐Ternero, Reshma S. Baliga, Nicola Smart, Adrian J. Hobbs   +7 more
openalex   +1 more source

Multidisciplinary Therapy to Target Obesity and Its Complications in Adult Population: A Narrative Review

Obesity Reviews, EarlyView.
ABSTRACT Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling.
Ana Raimunda Dâmaso, Flávia Campos Corgosinho, Deborah Cristina Landi Masquio, Nayra Figueiredo, Fabiana Kattah, Cintia Cercato, Lian Tock, Raquel Munhoz da Silveira Campos   +7 more
wiley   +1 more source

NT‐proBNP With Postoperative Complications and 2‐Year Mortality Among Hip Fracture Patients: An Observational Cohort Study

Orthopaedic Surgery, EarlyView.
Preoperative NT‐proBNP is strongly associated with both postoperative complications and 2‐year all‐cause mortality among patients who received hip fracture surgery. Higher levels of NT‐proBNP before surgery may serve as a useful biomarker for risk stratification and guiding treatment decisions for this patient subpopulation.
Xisheng Lin, Yu Jiang, Yilin Wang, Shuhuai Tan, Xiang Cui, Yan Luo, Houchen Lyu, Licheng Zhang, Peifu Tang   +8 more
wiley   +1 more source

Predictors of Atrial High‐Rate Episodes and Inappropriate Device Therapy in Implantable Cardioverter Defibrillators

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Implantable cardioverter defibrillator (ICD) therapy can prevent sudden cardiac death, but poses a risk of inappropriate device therapy (IDT), which is linked to worse outcomes and reduced quality of life. On the other hand, ICDs can function as an early warning system for atrial arrhythmias.
Marthe J. Huntelaar, Luuk H. G. A. Hopman, Anne‐Lotte C. J. van der Lingen, Mischa T. Rijnierse, Michiel J. B. Kemme, Cornelis P. Allaart, Vokko P. van Halm   +6 more
wiley   +1 more source

Analytical Validation of a Novel Point‐Of‐Care Quantitative Immunoassay for Feline N‐Terminal Pro‐Brain Natriuretic Peptide

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background Point‐of‐care testing (POC) is widely utilized for rapid results for many different analytes. A new feline‐specific N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) quantitative assay (Vcheck V200, Bionote Inc) is currently available but has not undergone independent validation.
Emily A. Javery, Ryan C. Fries, Saki Kadotani, Leah Kruckman, Lindsey Humphries, Sumana R. Prabhakar, Michael F. Rosser   +6 more
wiley   +1 more source

Establishment of a mouse model for ischaemic heart failure induced by coronary microembolization via left ventricular oil injection

Experimental Physiology, EarlyView.
Abstract Over the past three decades, there has been a steady increase in clinical attention to ischaemic heart failure caused by coronary microembolization. Nonetheless, a suitable mouse model for studying this condition remains limited. In the present study, we developed a mouse model of coronary microembolization‐induced ischaemic heart failure by ...
Lang Pei, Yusheng Hong, Qiuyue Wu, Jianyi Lv, Changlong Li, Xueyun Huo, Xin Liu, Di Zhang, Meng Guo, Zhenwen Chen, Xiaoyan Du   +10 more
wiley   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source