Results 1 to 10 of about 69,627 (265)
C-Type Natriuretic Peptide Derivatives: Orthopaedic Implications in Achondroplasia [PDF]
Journal of the Pediatric Orthopaedic Society of North America: The recent development of C-type natriuretic peptide (CNP) analogs to increase growth velocity in achondroplasia is now being used alongside limb lengthening procedures.
Emily Qian, MS +3 more
doaj +2 more sources
C-Type Natriuretic Peptide in Essential Hypertension
JACC: Basic to Translational Science, 2023 Summary: Multiple mechanisms are involved in essential hypertension. Antihypertensive drugs mainly target increased activity of the sympathetic nervous system, altered production of vasoactive mediators, vascular inflammation, fibrosis, and increased ...
Tara Perunovic, BM +1 more
doaj +1 more source
Pathogenetic justification of sacubitril / valsartan use in respiratory-cardial comorbidity
Patologìâ, 2023 Among the comorbid conditions that significantly worsen quality of life and life expectancy are the chronic obstructive pulmonary disease and heart failure.
T. V. Ashcheulova +3 more
doaj +1 more source
Biology, 2022 The field of natriuretic peptides (NPs) as an endocrine hormone has been developing since 1979. There are three peptides in humans: atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP), which bind to the guanylyl cyclase-A (GC-A ...
Tomoko Ichiki +2 more
doaj +1 more source
Molecular Mechanism of Blood Pressure Regulation through the Atrial Natriuretic Peptide
Biology, 2022 Natriuretic peptides, including atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), have cardioprotective effects and regulate blood pressure in mammals.
Takeshi Tokudome, Kentaro Otani
doaj +1 more source
AC-NP: a novel chimeric peptide with natriuretic and vasorelaxing actions. [PDF]
PLoS ONE, 2011 The aim of this study was to evaluate the cardiovascular and renal activities of a newly designed natriuretic peptide (NP). Here, we engineered a novel 28-amino acid chimeric peptide, termed AC-NP that combined the 17-amino acid ring of C type ...
Bao-Ying Chen +9 more
doaj +1 more source
Physiological and Pathophysiological Effects of C-Type Natriuretic Peptide on the Heart
Biology, 2022 C-type natriuretic peptide (CNP) is the third member of the natriuretic peptide family. Unlike other members, i.e., atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), which are cardiac hormones secreted from the atrium and ventricle of
Akihiro Yasoda
doaj +1 more source
Do N-Terminal Pro-C-Type Natriuretic Peptide Levels Relate to Severity of Preeclampsia?
International Journal of Hypertension, 2020 Aim. To compare the plasma N-terminal pro-C-type natriuretic peptide concentrations of normotensive pregnant women, patients with mild preeclampsia, and patients with severe preeclampsia. Methods.
Dogan Vatansever +4 more
doaj +1 more source
Roles of Natriuretic Peptides and the Significance of Neprilysin in Cardiovascular Diseases
Biology, 2022 Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) activate the guanylyl cyclase A receptor (GC-A), which synthesizes the second messenger cGMP in a wide variety of tissues and cells.
Hitoshi Nakagawa, Yoshihiko Saito
doaj +1 more source
Frontiers in Veterinary Science, 2022 During infection, the infected tissue secretes a variety of endogenous peptides to resist further invasion of pathogens. Among these endogenous peptides, the natriuretic peptides and the antimicrobial peptides attracted the most attention.
Mingzhen Fan +15 more
doaj +1 more source