Results 1 to 10 of about 69,767 (155)

Cenderitide-eluting film for potential cardiac patch applications.

PLoS ONE, 2013
Cenderitide, also known as CD-NP, is a designer peptide developed by combining native mammalian c-type natriuretic peptide (CNP) and the C-terminus isolated from the dendroapis natriuretic peptide (DNP) of the venom from the green mamba. In early studies,
Xu Wen Ng, Yingying Huang, Horng H Chen, John C Burnett, Freddy Y C Boey, Subbu S Venkatraman   +5 more
doaj   +1 more source

NPs/NPRs Signaling Pathways May Be Involved in Depression-Induced Loss of Gastric ICC by Decreasing the Production of mSCF.

PLoS ONE, 2016
It is well known that natriuretic peptides (NPs) are involved in the regulation of gastrointestinal motility. Interstitial cells of Cajal (ICC) are the pacemaker cells of gastrointestinal motility and gastrointestinal dyskinesia is one of the important ...
Xue-Lian Lin, Xu-Dong Tang, Zheng-Xu Cai, Feng-Yun Wang, Ping Li, Hua Sui, Hui-Shu Guo   +6 more
doaj   +1 more source

Pseudomonas aeruginosa Expresses a Functional Human Natriuretic Peptide Receptor Ortholog: Involvement in Biofilm Formation

mBio, 2015
Considerable evidence exists that bacteria detect eukaryotic communication molecules and modify their virulence accordingly. In previous studies, it has been demonstrated that the increasingly antibiotic-resistant pathogen Pseudomonas aeruginosa can ...
Thibaut Rosay, Alexis Bazire, Suraya Diaz, Thomas Clamens, Anne-Sophie Blier, Lily Mijouin, Brice Hoffmann, Jacques-Aurélien Sergent, Emeline Bouffartigues, Wilfrid Boireau, Julien Vieillard, Christian Hulen, Alain Dufour, Nicholas J. Harmer, Marc G. J. Feuilloley, Olivier Lesouhaitier   +15 more
doaj   +1 more source

C-Type Natriuretic Peptide/Natriuretic Peptide Receptor 2 Is Involved in Cell Proliferation and Testosterone Production in Mouse Leydig Cells

The World Journal of Men's Health, 2019
Purpose: This study investigated the role of natriuretic peptide receptor 2 (NPR2) on cell proliferation and testosterone secre-tion in mouse Leydig cells.Materials and Methods: Mouse testis of different postnatal stages was isolated to detect the ...
Lei Yang, Lanjie Lei, Qihan Zhao, Ying Gong, Gaopeng Guan, Shaoxin Huang   +5 more
doaj   +1 more source

CLINICAL AND DIAGNOSTIC VALUE OF STUDIES OF ENDOTHELIAL DYSFUNCTION MARKERS IN PATIENTS WITH ISCHEMIC HEART DISEASE

Кубанский научный медицинский вестник, 2014
In this paper we have carried out the diagnosis of the damage of the vascular endothelium in patients with ischemic heart disease (IHD) based on the study of gene of endothelial nitric oxide synthase polymorphism, the condition of vasoregulating function
A. Kh. Akhmineeva, O. S. Polunina, L. P. Voronina, I. V. Sevostyanova   +3 more
doaj  

Novel Stochastic Sensors Based on Phthalocyanine Complexes for the Detection of C-NP, IL-6, and CRP in Cardiovascular Diseases

Life
The severity of cardiovascular disease is linked to C-reactive protein, interleukin 6, and C-type natriuretic peptide levels, stressing the need for a sensitive sensor that can detect these biomarkers at ultralow levels in real time.
Ruxandra-Maria Ilie-Mihai, Raluca-Ioana Stefan-van Staden   +1 more
doaj   +1 more source

A novel designer natriuretic peptide integrating human C‐type natriuretic peptide, atrial natriuretic peptide, and B‐type natriuretic peptide

The FASEB Journal, 2009
Background The 17‐amino‐acid (AA) ring of C‐type natriuretic peptide (CNP) is essential for activation of NP receptor (NPR)‐B and the 2 nd messenger cGMP. CNP induces minimal hypotension as NPR‐B is more abundantly found in veins
Candace Y.W. Lee, John C. Burnett
openaire   +1 more source

Endothelium-derived C-type natriuretic peptide offsets the pathogenesis of pulmonary hypertension

Pharmacological Research
In the systemic circulation, C-type natriuretic peptide (CNP) fulfils a multimodal homeostatic function, modulating many processes relevant to pulmonary hypertension (PH), including local blood flow, vascular remodeling and cardiac function.
Joshua P. Dignam, Aisah A. Aubdool, Vanessa R. Lowe, C. Perez-Ternero, Amie J. Moyes, Reshma S. Nahal, Jigisha A. Patel, Lucie H. Clapp, Mario Böhm, Ralph T. Schermuly, Adrian J. Hobbs   +10 more
doaj   +1 more source

Natriuretic peptide system and cardiovascular disease

Heart Views, 2010
The mammalian Natriuretic Peptide (NP) system consists of neuro-hormones, such as atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), c-type natriuretic peptide (CNP), and the N-Terminal fragment of BNP (NT-pro-BNP).
Federico Cacciapuoti
doaj  

Beyond the pump: integrating the heart’s endocrine function into early medical education

Medical Education Online
Background The heart is commonly introduced in early medical education through its structural, mechanical, and electrophysiological roles. Although this framing remains foundational, it may underemphasize the heart’s endocrine functions.
JC Malsawmzuali, Fadi W. Adel, Wojciech Pawlina, Punnose Kattil   +3 more
doaj   +1 more source