Perspectives on C‐Type Natriuretic Peptide in Cardiometabolic Disease [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseAlthough CNP (C‐type natriuretic peptide) was first identified in brain tissue, its systemic expression and release is mainly located to the endothelial lining of the vasculature.
Jens P. Goetze +5 more
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C-Type Natriuretic Peptide in Essential Hypertension [PDF]
JACC: Basic to Translational Science, 2023 Summary: Multiple mechanisms are involved in essential hypertension. Antihypertensive drugs mainly target increased activity of the sympathetic nervous system, altered production of vasoactive mediators, vascular inflammation, fibrosis, and increased ...
Tara Perunovic, BM +1 more
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C-Type Natriuretic Peptide Derivatives: Orthopaedic Implications in Achondroplasia [PDF]
Journal of the Pediatric Orthopaedic Society of North America: The recent development of C-type natriuretic peptide (CNP) analogs to increase growth velocity in achondroplasia is now being used alongside limb lengthening procedures.
Emily Qian, MS +3 more
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Physiological and Pathophysiological Effects of C-Type Natriuretic Peptide on the Heart [PDF]
Biology, 2022 C-type natriuretic peptide (CNP) is the third member of the natriuretic peptide family. Unlike other members, i.e., atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), which are cardiac hormones secreted from the atrium and ventricle of
Akihiro Yasoda
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C-type natriuretic peptide preserves central neurological function by maintaining blood-brain barrier integrity [PDF]
Frontiers in Molecular Neuroscience, 2022 C-type natriuretic peptide (CNP) is highly expressed in the central nervous system (CNS) and key to neuronal development; however, a broader role for CNP in the CNS remains unclear.
Cristina Perez-Ternero +7 more
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Collagen-binding C-type natriuretic peptide enhances chondrogenesis and osteogenesis [PDF]
JCI InsightC-type natriuretic peptide (CNP) is known to promote chondrocyte proliferation and bone formation; however, CNP’s extremely short half-life necessitates continuous intravascular administration to achieve bone-lengthening effects. Vosoritide, a CNP analog
Kenta Hirai +14 more
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Pro-C-Type Natriuretic Peptide in Women With Angina Pectoris and No Obstructive Coronary Artery Disease [PDF]
JACC: AdvancesBackground: Circulating C-type natriuretic peptides (CNPs) predict adverse outcome in women presenting with ST-elevation myocardial infarction. Objectives: The purpose of this study was to determine the prognostic impact of a high proCNP concentration in
Peter D. Mark, MD, PhD +5 more
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C-type natriuretic peptide (CNP) in the paraventricular nucleus-mediated renal sympatho-inhibition [PDF]
Frontiers in Physiology, 2023 Volume reflex produces sympatho-inhibition that is mediated by the hypothalamic paraventricular nucleus (PVN). However, the mechanisms for the sympatho-inhibitory role of the PVN and the neurochemical factors involved remain to be identified.
Hong Zheng +3 more
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C-type natriuretic peptide regulates lipid metabolism through a NPRB-PPAR pathway in the intramuscular and subcutaneous adipocytes in chickens [PDF]
Scientific ReportsNatriuretic peptides (NPs) have an important role in lipid metabolism in skeletal muscle and adipose tissue in animals. C-type natriuretic peptide (CNP) is an important NP, but the molecular mechanisms that underlie its activity are not completely ...
Huayun Huang +7 more
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C-type natriuretic peptide: the heart's guardian angel. [PDF]
Eur Heart J, 2020 Abstract
Sangaralingham SJ, Chen Y, Burnett JC.
europepmc +3 more sources