Results 41 to 50 of about 69,627 (255)

Cell surface protein disulfide isomerase regulates natriuretic peptide generation of cyclic guanosine monophosphate. [PDF]

PLoS ONE, 2014
The family of natriuretic peptides (NPs), including atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), exert important and diverse actions for cardiovascular and renal homeostasis.
Shuchong Pan, Horng H Chen, Cristina Correia, Haiming Dai, Tyra A Witt, Laurel S Kleppe, John C Burnett, Robert D Simari   +7 more
doaj   +1 more source

Algorithm for Diagnosing Cardiovascular Pathology in Diabetes Mellitus

Juvenis Scientia, 2023
Introduction. The association of diabetes mellitus (DM) and cardiovascular diseases (CVD) is due to common pathophysiological processes that determine the prognosis and progression of both diseases.
Vasilkova, V.M., Mokhort, T.V., Savesteeva, I.G.   +2 more
doaj   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

Combination of Amino‐Terminal Pro‐BNP, Estimated GFR, and High‐Sensitivity CRP for Predicting Cardiorenal Syndrome Type 1 in Acute Myocardial Infarction Patients

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Cardiorenal syndrome type 1 (CRS1) as a complication of acute myocardial infarction can lead to adverse outcomes, and a method for early detection is needed. This study investigated the individual and integrated effectiveness of amino‐terminal
De‐Qiang Zhang, Hong‐Wei Li, Hai‐Ping Chen, Qing Ma, Hui Chen, Yun‐Li Xing, Xue‐Qiao Zhao   +6 more
doaj   +1 more source

The Effects of C-type Natriuretic Peptide on Craniofacial Skeletogenesis [PDF]

Journal of Dental Research, 2012
C-type natriuretic peptide (CNP) is a potent stimulator of long bone and vertebral development via endochondral ossification. In the present study, we investigated the effects of CNP on craniofacial skeletogenesis, which consists of both endochondral and membranous ossification.
K, Nakao, Y, Okubo, A, Yasoda, N, Koyama, K, Osawa, Y, Isobe, E, Kondo, T, Fujii, M, Miura, K, Nakao, K, Bessho   +10 more
openaire   +2 more sources

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Prognostic value of biomarkers in chronic heart failure with preserved left ventricular ejection fraction [PDF]

Терапевтический архив, 2016
The paper reviews major biomarkers for determining the prognosis in patients with chronic heart failure and preserved ejection fraction. It also considers cystatin C, one of the novel and probably the most practically important biomarkers.
T A Nikiforova, D Yu Shchekochikhin, F Yu Kopylov, A L Syrkin   +3 more
doaj   +1 more source

Measurement of Pro-C-Type Natriuretic Peptide in Plasma [PDF]

Clinical Chemistry, 2005
Accurate measurement of peptides derived from pro-C-type natriuretic peptide (proCNP) in human plasma has been difficult for several reasons. Low plasma concentrations necessitate high assay sensitivity. In addition, sufficient specificity can be difficult because of the close sequence homology of CNP with atrial natriuretic peptide (ANP) and B-type ...
Soren Junge, Nielsen, Jens F, Rehfeld, Frants, Pedersen, Jens, Kastrup, Regitze, Videbaek, Jens Peter, Goetze   +5 more
openaire   +2 more sources

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

Natriuretic peptide B receptor and C-type natriuretic peptide in the rat kidney. [PDF]

Journal of the American Society of Nephrology, 1995
Natriuretic peptide receptor B (ANP-RGC(B)) has been previously identified in the kidney. It binds C-type natriuretic peptide (CNP) with high affinity and the two other natriuretic peptides (atrial natriuretic peptide and brain natriuretic peptide) with low affinity, and mediates the biological effects of CNP.
A, Lohe, I, Yeh, T, Hyver, R, Pratt, R, Jamison   +4 more
openaire   +2 more sources