Results 11 to 20 of about 69,627 (265)

Perspectives on C‐Type Natriuretic Peptide in Cardiometabolic Disease [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Although CNP (C‐type natriuretic peptide) was first identified in brain tissue, its systemic expression and release is mainly located to the endothelial lining of the vasculature.
Jens P. Goetze, Hiromu Yanagisawa, Hideyuki Kinoshita, John Burnett, Michael Nyberg, Toshio Nishikimi   +5 more
doaj   +3 more sources

Mismeasure of C-Type Natriuretic Peptide [PDF]

Clinical Chemistry, 2008
It has been difficult to establish an endocrine role for C-type natriuretic peptide (CNP). Release of CNP from the heart remains to be convincingly demonstrated (1)(2)(3)(4)(5), and data concerning CNP in cardiac disease have been conflicting, possibly because of specificity problems in measurement of CNP.
Nielsen, S.J., Goetze, J.P., Rehfeld, Jens Frederik   +2 more
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C-Type Natriuretic Peptides in Coronary Disease [PDF]

Clinical Chemistry, 2017
Abstract AIMS C-type natriuretic peptide (CNP) is a paracrine growth factor expressed in the vascular endothelium. Although upregulated in atheromatous arteries, the predictive value of plasma CNP products for outcome in coronary disease is unknown.
Timothy C R, Prickett, Robert N, Doughty, Richard W, Troughton, Chris M, Frampton, Gillian A, Whalley, Chris J, Ellis, Eric A, Espiner, A Mark, Richards   +7 more
openaire   +2 more sources

C-type natriuretic peptide preserves central neurological function by maintaining blood-brain barrier integrity

Frontiers in Molecular Neuroscience, 2022
C-type natriuretic peptide (CNP) is highly expressed in the central nervous system (CNS) and key to neuronal development; however, a broader role for CNP in the CNS remains unclear.
Cristina Perez-Ternero, Patrick N. Pallier, Jordi L. Tremoleda, Alessio Delogu, Cathy Fernandes, Cathy Fernandes, Adina T. Michael-Titus, Adrian J. Hobbs   +7 more
doaj   +1 more source

Natriuretic peptides: Diagnostic and therapeutic use

Indian Journal of Endocrinology and Metabolism, 2011
Natriuretic peptides (NPs) are hormones which are mainly secreted from heart and have important natriuretic and kaliuretic properties. There are four different groups NPs identified till date [atrial natriuretic peptide (ANP), B-type natriuretic peptide (
Kaushik Pandit, Pradip Mukhopadhyay, Sujoy Ghosh, Subhankar Chowdhury   +3 more
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Factors influencing left ventricular ejection fraction in patients with coronary microvascular disease and obstructive coronary artery disease

BMC Research Notes, 2020
Objective The aim of our research was to evaluate the relationship involving left ventricular ejection fraction, low density lipoprotein, B-type natriuretic peptide, Troponin I and coronary flow reserve, and to determine the predictors of left ...
Henry Anselmo Mayala, Magesa Mafuru, Abdalah Mkangala, Mark Mayala, Pedro Pallangyo, Dickson Minja, Mohamed Janabi, Wang Zhao-hui   +7 more
doaj   +1 more source

CNP, the Third Natriuretic Peptide: Its Biology and Significance to the Cardiovascular System

Biology, 2022
The natriuretic peptide family consists of three biologically active peptides: ANP, BNP, and CNP. CNP is more widely expressed than the other two peptides, with significant levels in the central nervous system, osteochondral system, and vascular system ...
Yasuaki Nakagawa, Toshio Nishikimi
doaj   +1 more source

Framingham and American College of Cardiology/American Heart Association Pooled Cohort Equations, High‐Sensitivity Troponin T, and N‐Terminal Pro–Brain‐Type Natriuretic Peptide for Predicting Atherosclerotic Cardiovascular Events Across the Spectrum of Kidney Dysfunction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Contemporary guidelines recommend using atherosclerotic cardiovascular disease screening tools to guide primary prevention. The performance of these scores is not well known in patients with moderate to advanced chronic kidney disease ...
Benjamin Lidgard, Leila R. Zelnick, Alan Go, Kevin D. O’Brien, Nisha Bansal   +4 more
doaj   +1 more source

C-type natriuretic peptide moderates titin-based cardiomyocyte stiffness

JCI Insight, 2020
Heart failure is often accompanied by titin-dependent myocardial stiffness. Phosphorylation of titin by cGMP-dependent protein kinase I (PKGI) increases cardiomyocyte distensibility.
Konstanze Michel, Melissa Herwig, Franziska Werner, Katarina Špiranec Spes, Marco Abeßer, Kai Schuh, Swati Dabral, Andreas Mügge, Hideo A. Baba, Boris V. Skryabin, Nazha Hamdani, Michaela Kuhn   +11 more
doaj   +1 more source

The oocyte cumulus complex regulates mouse sperm migration in the oviduct

Communications Biology, 2022
Oocyte-dependent and cumulus cell-derived transforming growth factor-β promotes natriuretic peptide type C expression in mouse ampullary epithelial cells, which promotes sperm migration into the ampulla for fertilization.
Zhijuan Wang, Hongwei Wei, Zhanying Wu, Xiaodan Zhang, Yanli Sun, Longwei Gao, Wenqing Zhang, You-Qiang Su, Meijia Zhang   +8 more
doaj   +1 more source