Results 71 to 80 of about 168,641 (363)

C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro [PDF]

, 2015
Subjects carrying the T2238C ANP gene variant have a higher risk to suffer a stroke or myocardial infarction. The mechanisms through which T2238C/αANP exerts detrimental vascular effects need to be fully clarified.
Bianchi, Franca, Cotugno, Maria, DI CASTRO, SARA, FRATI, GIACOMO, MARCHITTI, Simona, RUBATTU, Speranza Donatella, SCARPINO, Stefania, SCIARRETTA, SEBASTIANO, Stanzione, Rosita, VOLPE, Massimo   +9 more
core   +1 more source

The Effects of C-type Natriuretic Peptide on Craniofacial Skeletogenesis [PDF]

Journal of Dental Research, 2012
C-type natriuretic peptide (CNP) is a potent stimulator of long bone and vertebral development via endochondral ossification. In the present study, we investigated the effects of CNP on craniofacial skeletogenesis, which consists of both endochondral and membranous ossification.
K, Nakao, Y, Okubo, A, Yasoda, N, Koyama, K, Osawa, Y, Isobe, E, Kondo, T, Fujii, M, Miura, K, Nakao, K, Bessho   +10 more
openaire   +3 more sources

Vascularized and Perfusable Human Heart‐on‐a‐Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery

Advanced Materials, EarlyView.
This novel 3D human ischemic heart‐on‐a‐chip, with perfusable vasculature directly interfaced with myocardial tissue, replicates key aspects of ischemic heart injury. It also demonstrates the targeted delivery and therapeutic efficacy of cardiac homing peptide‐conjugated liposomes, validating the platform for drug and nanomedicine screening in ...
Junyoung Kim, Xuening Zhang, Richard Wang, Adrian Najer, Qiao You Lau, Ana Cammack‐Najera, Jang Ah Kim, Yoo Kyung Kang, Ruoxiao Xie, Hyemin Kim, Kai Xie, Hyeonji Lim, Tae‐Eun Park, Jinmyoung Joo, Molly M. Stevens   +14 more
wiley   +1 more source

Genome-Wide Association with Select Biomarker Traits in the Framingham Heart Study [PDF]

, 2007
BACKGROUND: Systemic biomarkers provide insights into disease pathogenesis, diagnosis, and risk stratification. Many systemic biomarker concentrations are heritable phenotypes.
Benjamin, Emelia J., Booth, Sarah L., Dupuis, Josée, Govindaraju, Diddahally R., Kathiresan, Sekar, Keaney, John F., Keyes, Michelle J., Larson, Martin G., Lin, Jing-Ping, Lunetta, Kathryn L., Meigs, James B., Robins, Sander J., Rong, Jian, Schnabel, Renate, Vasan, Ramachandran S., Vita, Joseph A., Wang, Thomas J., Wilson, Peter W. F., Wolf, Philip A.   +18 more
core   +3 more sources

The Role of Artificial Intelligence in Advancing Biosensor Technology: Past, Present, and Future Perspectives

Advanced Materials, EarlyView.
This review explores the transformative role of AI in biosensor technology and provides a holistic interdisciplinary perspective that covers a broader scope of AI‐enabled biosensor technologies across various sectors including healthcare, environmental monitoring, food safety, and agriculture. It also highlights the important role of novel materials in
Tuğba Akkaş, Mahshid Reshadsedghi, Mustafa Şen, Volkan Kılıç, Nesrin Horzum   +4 more
wiley   +1 more source

C-type natriuretic peptide enhances mouse preantral follicle growth.

Reproduction, 2019
Compared to ovarian antral follicle development, the mechanism underlying preantral follicle growth has not been well documented. Although C-type natriuretic peptide (CNP) involvement in preantral folliculogenesis has been explored, its detailed role has
Guangyin Xi, W. Wenjing, Fazlani Sarfaraz A, Yao Fusheng, Yang Mingyao, Jing Hao, An Lei, Jianhui Tian   +7 more
semanticscholar   +1 more source

Altered density of glomerular binding sites for atrial natriuretic factor in bile duct-ligated rats with ascites [PDF]

, 1991
The renal response to atrial natriuretic factor is blunted in cirrhosis with ascites. This might be due to alterations of renal receptors for atrial natriuretic factor.
Almeida, Arendt, Arendt, Ballermann, Cantin, Chinkers, De Léan, Epstein, Garcia, Gauquelin, Gauquelin, Gerbes, Gerbes, Gerbes, Gerbes, Gines, Kollenda, Kollenda, Kountouras, Laffi, Lang, Lowry, Maack, Misra, Morgan, Munson, Needleman, Olivera, Panos, Petrillo, Salerno, Thibault   +31 more
core   +1 more source

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

Advanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang, Yongfei Song, Xiaojun Jin, Qingbo Xu, Honghua Ye, Zhuonan Wu, Hui Lin, Jiale Hu, Chen Huang, Jianqing Zhou, Jiangfang Lian   +10 more
wiley   +1 more source

C-type natriuretic peptide ameliorates pulmonary fibrosis by acting on lung fibroblasts in mice

Respiratory Research, 2016
BackgroundPulmonary fibrosis has high rates of mortality and morbidity; however, no effective pharmacological therapy has been established. C-type natriuretic peptide (CNP), a member of the natriuretic peptide family, selectively binds to the ...
Toru Kimura, T. Nojiri, J. Hino, H. Hosoda, K. Miura, Y. Shintani, M. Inoue, Masahiro Zenitani, H. Takabatake, M. Miyazato, M. Okumura, K. Kangawa   +11 more
semanticscholar   +1 more source

Neuropeptides in the Extracellular Space of the Mouse Cortex Measured In Vivo by Nanodialysis Probe Coupled with LC‐MS

Angewandte Chemie, EarlyView.
This study reveals a complex peptidomic landscape in the mouse somatosensory cortex, identifying locally released and potentially transported neuropeptides using a membrane‐free nanodialysis sampling probe coupled with nanoLC‐timsTOF mass spectrometry.
Keyin Li, Weihua Shi, Yanqi Tan, Yu Ding, Alex G. Armstrong, Yurii Vlasov, Jonathan V. Sweedler   +6 more
wiley   +2 more sources