Results 271 to 280 of about 19,786,213 (303)
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Evolution of lifespan in C. elegans
Nature, 2000It was proposed almost 50 years ago that ageing is non-adaptive and is the consequence of a decline in the force of natural selection with age1. This led to the theory that ageing results from detrimental effects late in life of genes that act beneficially in early life1,2, so any genetic alteration that increases lifespan might be expected to reduce ...
D W, Walker +4 more
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C. elegans Embryonic Morphogenesis
2016Morphogenesis is a four-dimensional process which involves the crucial interplay between signaling, mechanical forces, and spatial changes. Caenorhabditis elegans presents a simple yet versatile model to study morphogenesis. Here, we review recent progress on cellular and molecular drivers of morphological changes during C.
Vuong-Brender, Thanh T. K. +2 more
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Patterning in the C. elegans embryo
Trends in Genetics, 1994Recent studies reveal preliminary insights into the mechanisms of embryonic patterning in Caenorhabditis elegans. It appears that both embryonic axes and early blastomere fates are determined by a combination of segregating determinants and cell interactions, under the control of maternally expressed genes.
W B, Wood, L G, Edgar
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Axon degeneration in c. elegans
2018Axons degenerate following injury and during "dying-back" neurodegenerative diseases, which are characterized by early degeneration of synapses and axons. While injury and disease are clearly distinct events, they share some common regulators. Although these problems have been extensively studied, very little is known about which molecules initiate and
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Xenobiotic metabolism and transport in Caenorhabditis elegans
Journal of Toxicology and Environmental Health - Part B: Critical Reviews, 2021Stefan Taubert +2 more
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[C. elegans defence mechanisms].
Medecine sciences : M/S, 2009The nematode Caenorhabditis elegans has evolved as a powerful invertebrate model to study innate immunity to pathogens. C. elegans possesses inducible defence mechanisms to protect itself from pathogenic attack, mainly by the production of antimicrobial effector molecules.
Ziegler, Katja, Pujol, Nathalie
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Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity
Nature Genetics, 2012Joshua Shapiro, Joshua S. Bloom
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A living model for obesity and aging research: Caenorhabditis elegans
Critical Reviews in Food Science and Nutrition, 2018Yiren Yue, Yeonhwa Park, Peiyi Shen
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An essential role for XBP-1 in host protection against immune activation in C. elegans
Nature, 2010Dennis H Kim, Claire E Richardson
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