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Caenorhabditis elegans as a model for obesity research
Caenorhabditis elegans, a free-living nematode, is an animal model that has been extensively employed in a variety of research fields, including in the study of obesity. Its favorable features include its compact size, short life cycle, large brood size,
Yiren Yue +3 more
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Surface Acoustic Wave Induced Heat Knockdown of Caenorhabditis Elegans
Model organisms such as Caenorhabditis elegans are commonly used in discovering theunderlying mechanisms of human diseases. The field of microfluidics enables a plethora of tools for better studying these organisms.
Adem Özçelik
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Transparent, free-living nematode worm. Unsegmented body plan with full set of differentiated tissues (neural, endoderm, ectoderm and muscle). Genome size approximately 97 Mb, as five autosomes and one X sex chromosome. Fully sequenced genome, which comprises approximately 20 000 predicted genes. Defined cell lineage.
J, Wixon +4 more
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The genome of Caenorhabditis elegans. [PDF]
The physical map of the 100-Mb Caenorhabditis elegans genome consists of 17,500 cosmids and 3500 yeast artificial chromosomes (YACs). A total of 22.5 Mb has been sequenced, with the remainder expected by 1998. A further 15.5 Mb of unfinished sequence is freely available online: because the areas sequenced so far are relatively gene rich, about half the
Waterston, R., Sulston, J.
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Oogenesis in Caenorhabditis elegans
Background: The nematode, Caenorhabditis elegans has proven itself as a valuable model for investigating metazoan biology. C. elegans have a transparent body, an invariant cell lineage, and a high level of genetic conservation which makes it a desirable model organism.
Davis, Gregory M. +2 more
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Reproductive Span of Caenorhabditis elegans Is Extended by Microbacterium sp.
The reproductive span (RS) of organisms could be affected by different factors during their lifetime. In the model nematode, Caenorhabditis elegans, RS is affected by both genetic and environmental factors.
Le Tho Son +7 more
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Proteomics in Caenorhabditis elegans [PDF]
Proteomic approaches are increasingly being used to complement genetic and RNA interference-based studies of gene function in Caenorhabditis elegans. Several strategies to isolate protein complexes from whole worms and individual differentiated cell types have been described.
Anjon, Audhya, Arshad, Desai
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Immunosenescence in Caenorhabditis elegans
AbstractImmunosenescence is an age-dependent decline in immune functions and hallmark of aging in diverse species, ranging from invertebrates to mammals. However, identifying the factors responsible for immunosenescence is challenging because of the complexity of immune systems and aging in mammals.
Sieun S. Kim +2 more
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Objective: Under the guidance of model organism Caenorhabditis elegans with fine olfactory system, small molecular metabolites sensitive to high dose radiation were screened as biomarkers of acute radiation-induced injury, and their metabolic pathways ...
Xin Wu +4 more
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Detection of Pathogens and Regulation of Immunity by the Caenorhabditis elegans Nervous System
Although Caenorhabditis ...
Yiyong Liu, Jingru Sun
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