Results 11 to 20 of about 166,401 (268)

Caenorhabditis elegans as a model for obesity research

open access: yesCurrent Research in Food Science, 2021
Caenorhabditis elegans, a free-living nematode, is an animal model that has been extensively employed in a variety of research fields, including in the study of obesity. Its favorable features include its compact size, short life cycle, large brood size,
Yiren Yue   +3 more
doaj   +1 more source

A proteomic analysis of lipid raft and GPI anchored proteins in Caenorhabditis elegans [PDF]

open access: yes, 2010
Glycosylphosphatidylinositol (GPI) anchored proteins are a unique group of membrane proteins found on the surface and certain intracellular compartments of eukaryotic cells.
Rao, Wei
core   +6 more sources

Surface Acoustic Wave Induced Heat Knockdown of Caenorhabditis Elegans

open access: yesHittite Journal of Science and Engineering, 2021
Model organisms such as Caenorhabditis elegans are commonly used in discovering theunderlying mechanisms of human diseases. The field of microfluidics enables a plethora of tools for better studying these organisms.
Adem Özçelik
doaj   +1 more source

Caenorhabditis elegans [PDF]

open access: yesYeast, 2000
Transparent, free-living nematode worm. Unsegmented body plan with full set of differentiated tissues (neural, endoderm, ectoderm and muscle). Genome size approximately 97 Mb, as five autosomes and one X sex chromosome. Fully sequenced genome, which comprises approximately 20 000 predicted genes. Defined cell lineage.
J, Wixon   +4 more
openaire   +2 more sources

Immunosenescence in Caenorhabditis elegans

open access: yesImmunity & Ageing, 2022
AbstractImmunosenescence is an age-dependent decline in immune functions and hallmark of aging in diverse species, ranging from invertebrates to mammals. However, identifying the factors responsible for immunosenescence is challenging because of the complexity of immune systems and aging in mammals.
Sieun S. Kim   +2 more
openaire   +3 more sources

The genome of Caenorhabditis elegans. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1995
The physical map of the 100-Mb Caenorhabditis elegans genome consists of 17,500 cosmids and 3500 yeast artificial chromosomes (YACs). A total of 22.5 Mb has been sequenced, with the remainder expected by 1998. A further 15.5 Mb of unfinished sequence is freely available online: because the areas sequenced so far are relatively gene rich, about half the
Waterston, R., Sulston, J.
openaire   +2 more sources

The ecological genetics of senescence and stress resistance in Caenorhabditis elegans [PDF]

open access: yes, 2010
Longevity and the rate of senescence are determined by the ecological conditions during a population's recent evolutionary history, and are intrinsically linked to other components of life history and to fitness.
Savory, Fiona Rachel
core   +6 more sources

Reproductive Span of Caenorhabditis elegans Is Extended by Microbacterium sp.

open access: yesJournal of Nematology, 2022
The reproductive span (RS) of organisms could be affected by different factors during their lifetime. In the model nematode, Caenorhabditis elegans, RS is affected by both genetic and environmental factors.
Le Tho Son   +7 more
doaj   +1 more source

Oogenesis in Caenorhabditis elegans

open access: yesSexual Development, 2023
Background: The nematode, Caenorhabditis elegans has proven itself as a valuable model for investigating metazoan biology. C. elegans have a transparent body, an invariant cell lineage, and a high level of genetic conservation which makes it a desirable model organism.
Davis, Gregory M.   +2 more
openaire   +3 more sources

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

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