Results 11 to 20 of about 118,692 (314)

Caenorhabditis elegans [PDF]

Yeast, 2000
Transparent, free-living nematode worm. Unsegmented body plan with full set of differentiated tissues (neural, endoderm, ectoderm and muscle). Genome size approximately 97 Mb, as five autosomes and one X sex chromosome. Fully sequenced genome, which comprises approximately 20 000 predicted genes. Defined cell lineage.
J, Wixon, M, Blaxter, I, Hope, R, Barstead, S, Kim   +4 more
openaire   +2 more sources

Oogenesis in Caenorhabditis elegans

Sexual Development, 2023
Background: The nematode, Caenorhabditis elegans has proven itself as a valuable model for investigating metazoan biology. C. elegans have a transparent body, an invariant cell lineage, and a high level of genetic conservation which makes it a desirable model organism.
Davis, Gregory M., Hipwell, Hayleigh, Boag, Peter R.   +2 more
openaire   +3 more sources

Proteomics in Caenorhabditis elegans [PDF]

Briefings in Functional Genomics and Proteomics, 2008
Proteomic approaches are increasingly being used to complement genetic and RNA interference-based studies of gene function in Caenorhabditis elegans. Several strategies to isolate protein complexes from whole worms and individual differentiated cell types have been described.
Anjon, Audhya, Arshad, Desai
openaire   +2 more sources

Immunosenescence in Caenorhabditis elegans

Immunity & Ageing, 2022
AbstractImmunosenescence is an age-dependent decline in immune functions and hallmark of aging in diverse species, ranging from invertebrates to mammals. However, identifying the factors responsible for immunosenescence is challenging because of the complexity of immune systems and aging in mammals.
Sieun S. Kim, Jooyeon Sohn, Seung-Jae V. Lee   +2 more
openaire   +3 more sources

The genome of Caenorhabditis elegans. [PDF]

Proceedings of the National Academy of Sciences, 1995
The physical map of the 100-Mb Caenorhabditis elegans genome consists of 17,500 cosmids and 3500 yeast artificial chromosomes (YACs). A total of 22.5 Mb has been sequenced, with the remainder expected by 1998. A further 15.5 Mb of unfinished sequence is freely available online: because the areas sequenced so far are relatively gene rich, about half the
Waterston, R., Sulston, J.
openaire   +2 more sources

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Globins in Caenorhabditis elegans

IUBMB Life, 2011
AbstractExtensive in silico search of the genome of Caenorhabditis elegans revealed the presence of 33 genes coding for globins that are all transcribed. These globins are very diverse in gene and protein structure and are localized in a variety of cells, mostly neurons. The large number of C.
Tilleman, L, Germani, F, De Henau, S, Geuens, E, Hoogewijs, D, Braeckman, B P, Vanfleteren, J R, Moens, L, Dewilde, S   +8 more
openaire   +5 more sources

Dielectrophoresis of Caenorhabditis elegans [PDF]

Lab on a Chip, 2011
We demonstrate for the first time the dielectrophoretic trapping and manipulation of a whole animal, the nematode Caenorhabditis elegans. We studied the effect of the electric field on the nematode as a function of field intensity and frequency. We identified a range of electric field intensities and frequencies that trap worms without apparent adverse
Han-Sheng, Chuang, David M, Raizen, Annesia, Lamb, Nooreen, Dabbish, Haim H, Bau   +4 more
openaire   +2 more sources

A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans [PDF]

, 2004
Molting is required for progression between larval stages in the life cycle of nematodes. We have identified four mutant alleles of a <i>Caenorhabditis elegans</i> metalloprotease gene, <i>nas-37</i>, that cause incomplete ...
Jorgensen, A.M., Jorgensen, EM, Page, AP, Chan, A.C., Davis, MW, Chan, AC, Page, A.P., Birnie, AJ, Birnie, A.J., Davis, M.W.   +9 more
core   +1 more source

Patterns of nucleotide polymorphism distinguish temperate and tropical wild isolates of Caenorhabditis briggsae [PDF]

, 2006
Caenorhabditis briggsae provides a natural comparison species for the model nematode C. elegans, given their similar morphology, life history, and hermaphroditic mode of reproduction. Despite C.
Cutter, Asher, Cutter, Asher D., Felix, Marie-Anne, Barriere, Antoine, Charlesworth, Deborah   +4 more
core   +1 more source