Results 1 to 10 of about 1,677,918 (307)

Hyperactive ice-binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans. [PDF]

FEBS Open Bio
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Shimose D, Ozaki K, Kuriyama R, Ikemoto Y, Mio K, Sasaki YC, Arai T, Tsuda S, Shinkai Y, Kuramochi M.   +9 more
europepmc   +3 more sources

RNAi targeting Caenorhabditis elegans α-arrestins has small or no effects on lifespan [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2017
Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization.
Sangsoon Park, Yoonji Jung, Seon Woo A. An, Heehwa G. Son, Wooseon Hwang, Dongyeop Lee, Murat Artan, Hae-Eun H. Park, Dae-Eun Jeong, Yujin Lee, Seung-Jae V. Lee   +10 more
doaj   +1 more source

CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans.

PLoS ONE, 2019
Due to its ease of genetic manipulation and transparency, Caenorhabditis elegans (C. elegans) has become a preferred model system to study gene function by microscopy.
Brian J Thomas, Ira E Wight, Wendy Y Y Chou, Marco Moreno, Zachary Dawson, Arielle Homayouni, Huiyan Huang, Hyori Kim, Hanna Jia, Justin R Buland, Jennifer A Wambach, F Sessions Cole, Stephen C Pak, Gary A Silverman, Cliff J Luke   +14 more
doaj   +1 more source

RNAi targeting Caenorhabditis elegans α-arrestins has little effect on lifespan [version 4; referees: 2 approved, 1 approved with reservations]

F1000Research, 2017
Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization.
Sangsoon Park, Yoonji Jung, Seon Woo A. An, Heehwa G. Son, Wooseon Hwang, Dongyeop Lee, Murat Artan, Hae-Eun H. Park, Dae-Eun Jeong, Yujin Lee, Seung-Jae V. Lee   +10 more
doaj   +1 more source

TbUNC119 and its binding protein complex are essential for propagation, motility, and morphogenesis of Trypanosoma brucei procyclic form cells. [PDF]

PLoS ONE, 2010
Flagellum-mediated motility of Trypanosoma brucei is considered to be essential for the parasite to complete stage development in the tsetse fly vector, while the mechanism by which flagellum-mediated motility is controlled are not fully understood.
Shigeru Ohshima, Mitsuko Ohashi-Suzuki, Yutaka Miura, Yoshisada Yabu, Noriko Okada, Nobuo Ohta, Takashi Suzuki   +6 more
doaj   +1 more source

Neuronal calmodulin levels are controlled by CAMTA transcription factors

eLife, 2021
The ubiquitous Ca2+ sensor calmodulin (CaM) binds and regulates many proteins, including ion channels, CaM kinases, and calcineurin, according to Ca2+-CaM levels. What regulates neuronal CaM levels, is, however, unclear.
Thanh Thi Vuong-Brender, Sean Flynn, Yvonne Vallis, Saliha E Sönmez, Mario de Bono   +4 more
doaj   +1 more source

An SRR1 domain-containing protein is required for efficient Orsay virus replication in Caenorhabditis elegans

Journal of Virology
Viruses depend on their hosts for completing their life cycle, and a better understanding of virus replication can inform therapeutic strategies. Using the Orsay virus-Caenorhabditis elegans experimental platform, we identified by a forward genetic ...
Chika Fujii, David Wang
doaj   +1 more source

Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model

G3: Genes, Genomes, Genetics, 2016
The highly conserved cochaperone DnaJ/Hsp40 family proteins are known to interact with molecular chaperone Hsp70, and can regulate many cellular processes including protein folding, translocation, and degradation.
Seika Takayanagi-Kiya, Yishi Jin
doaj   +1 more source

Yolk-deprived Caenorhabditis elegans secure brood size at the expense of competitive fitness

Life Science Alliance, 2023
Many egg-laying species lower fecundity when yolk is in short supply, but not C. elegans . They still produce abundant offspring, yet of decreased quality. Oviparous animals support reproduction via the incorporation of yolk as a nutrient source into the
Ellen Geens, Pieter Van de Walle, Francesca Caroti, Rob Jelier, Christian Steuwe, Liliane Schoofs, Liesbet Temmerman   +6 more
doaj   +1 more source

Copper Homeostasis in the Model Organism C. elegans

Cells
Cellular and organismic copper (Cu) homeostasis is regulated by Cu transporters and Cu chaperones to ensure the controlled uptake, distribution and export of Cu ions.
Verena Alexia Ohse, Lars-Oliver Klotz, Josephine Priebs   +2 more
doaj   +1 more source