Immunoprecipitation of Proteins in Caenorhabditis elegans
Bio-Protocol, 2015 Immunoprecipitation (IP) is a biochemical technique to precipitate a protein out of solution using an antigen that can specifically bind to that protein.
Kevin Chan +3 more
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Identification and Functional Analysis of Cytokine-Like Protein CLEC-47 in Caenorhabditis elegans
mBio, 2021 A variety of effector proteins contribute to host defense in the nematode Caenorhabditis ...
Wen Pan +4 more
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Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes. [PDF]
PLoS Biology, 2009 The nematode Caenorhabditis elegans is a popular model system in genetics, not least because a majority of human disease genes are conserved in C. elegans.
Sabine P Schrimpf +12 more
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Nuclear/Cytoplasmic Fractionation of Proteins from Caenorhabditis elegans [PDF]
Bio-Protocol, 2018 C. elegans is widely used to investigate biological processes related to health and disease. To study protein localization, fluorescently-tagged proteins can be used in vivo or immunohistochemistry can be performed in whole worms.
Alejandro Mata-Cabana +3 more
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The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones. [PDF]
PLoS Genetics, 2016 Protein AMPylation by Fic domain-containing proteins (Fic proteins) is an ancient and conserved post-translational modification of mostly unexplored significance. Here we characterize the Caenorhabditis elegans Fic protein FIC-1 in vitro and in vivo. FIC-
Matthias C Truttmann +5 more
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Proteome-based investigation of O-GlcNAcylation in a C. elegans model of ageing and Alzheimer's disease: Functional support for earlier hypothesis-generating findings. [PDF]
PLoS ONEO-linked N-acetylglucosamine (O-GlcNAc) is a post-translational modification of serine and threonine residues on nuclear and cytoplasmic proteins. The identity of O-GlcNAcylated proteins during ageing and neurodegenerative disease remains incompletely ...
Fernando Garcia Olivera
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Prereplication complex proteins get caught moonlighting
PLoS Biology, 2022 In this issue of PLOS Biology, Lattmann and colleagues report a new function for proteins of the DNA prereplication complex promoting the anchor cell to invade through the basement membrane and initiate vulval development in Caenorhabditis elegans.
Hilary A. Coller
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G3: Genes, Genomes, Genetics, 2021 The visualization of biological processes using fluorescent proteins and dyes in living organisms has enabled numerous scientific discoveries.
Cori K Cahoon, Diana E Libuda
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Genetic analysis suggests a surface of PAT-4 (ILK) that interacts with UNC-112 (kindlin)
G3: Genes, Genomes, Genetics, 2022 Integrin plays a crucial role in the attachment of cells to the extracellular matrix. Integrin recruits many proteins intracellularly, including a 4-protein complex (kindlin, ILK, PINCH, and parvin).
Hiroshi Qadota +6 more
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Marine Drugs, 2021 With the widespread occurrence of aquaculture diseases and the broad application of antibiotics, drug-resistant pathogens have increasingly affected aquatic animals’ health.
Ying-Xiu Li +7 more
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