Results 21 to 30 of about 73,600 (228)
eLife, 2023 Argonaute (AGO) proteins associate with small RNAs to direct their effector function on complementary transcripts. The nematode Caenorhabditis elegans contains an expanded family of 19 functional AGO proteins, many of which have not been fully ...
Uri Seroussi +9 more
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Bio-Protocol, 2022 Membraneless organelles, such as germ granules and stress granules, are liquid-like condensates formed by phase transition. Recently, we and others have adopted proximity-based labeling methods to determine the composition of these membraneless ...
Hannah Hertz, Ian Price, Wen Tang
doaj +1 more source
Regulatory elements of Caenorhabditis elegans ribosomal protein genes [PDF]
BMC Genomics, 2012 Abstract Background Ribosomal protein genes (RPGs) are essential, tightly regulated, and highly expressed during embryonic development and cell growth. Even though their protein sequences are strongly conserved, their mechanism of regulation is not conserved across yeast, Drosophila, and vertebrates.
Sleumer Monica C +6 more
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Immunofluorescent Localization of Proteins in Caenorhabditis elegans Muscle [PDF]
, 2011 Caenorhabditis elegans is a premier model genetic system for discovering new information about the assembly and maintenance of striated muscle. The localization of a protein within a nematode muscle cell can reveal important clues to its function. In C.
Kristy J, Wilson +2 more
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Experimental considerations for study of C. elegans lysosomal proteins
G3: Genes, Genomes, Genetics, 2023 Lysosomes are an important organelle required for the degradation of a range of cellular components. Lysosome function is critical for development and homeostasis as dysfunction can lead to inherited genetic disorders, cancer, and neurodegenerative and ...
John C Clancy +5 more
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Auxin-mediated Protein Degradation in Caenorhabditis elegans
BIO-PROTOCOL, 2020 The auxin-inducible degron (AID) technology was recently adapted for use in the nematode Caenorhabditis elegans. Rapid degradation of C. elegans proteins tagged with an AID is mediated by a plant-specific F-box protein, transport inhibitor response 1 (TIR1), and occurs only in the presence of the phytohormone auxin.
Michael Martinez, David Matus
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Proteins interacting with Caenorhabditis elegans Gα subunits [PDF]
Comparative and Functional Genomics, 2003 AbstractTo identify novel components in heterotrimeric G‐protein signalling, we performed an extensive screen for proteins interacting with Caenorhabditis elegans Gα subunits. The genome of C. elegans contains homologues of each of the four mammalian classes of Gα subunits (Gs, Gi/o, Gq and G12), and 17 other Gα subunits.
Cuppen, E +3 more
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Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Lamin-Binding Proteins in Caenorhabditis elegans
, 2016 The nuclear lamina, composed of lamins and numerous lamin-associated proteins, is required for mechanical stability, mechanosensing, chromatin organization, developmental gene regulation, mRNA transcription, DNA replication, nuclear assembly, and nuclear positioning.
Dobrzynska, Agnieszka +2 more
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Global profiling of protein lactylation in Caenorhabditis elegans
PROTEOMICS, 2023 AbstractLactylation, as a novel posttranslational modification, is essential for studying the functions and regulation of proteins in physiological and pathological processes, as well as for gaining in‐depth knowledge on the occurrence and development of many diseases, including tumors.
Tao Ding +8 more
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