Results 21 to 30 of about 132,722 (276)

Potential conservation of circadian clock proteins in the phylum Nematoda as revealed by bioinformatic searches [PDF]

open access: yes, 2014
Although several circadian rhythms have been described in C. elegans, its molecular clock remains elusive. In this work we employed a novel bioinformatic approach, applying probabilistic methodologies, to search for circadian clock proteins of several of
A Claridge-Chang   +108 more
core   +11 more sources

Conditional immobilization for live imaging Caenorhabditis elegans using auxin-dependent protein depletion

open access: yesG3: Genes, Genomes, Genetics, 2021
The visualization of biological processes using fluorescent proteins and dyes in living organisms has enabled numerous scientific discoveries.
Cori K Cahoon, Diana E Libuda
doaj   +1 more source

Genetic analysis suggests a surface of PAT-4 (ILK) that interacts with UNC-112 (kindlin)

open access: yesG3: Genes, Genomes, Genetics, 2022
Integrin plays a crucial role in the attachment of cells to the extracellular matrix. Integrin recruits many proteins intracellularly, including a 4-protein complex (kindlin, ILK, PINCH, and parvin).
Hiroshi Qadota   +6 more
doaj   +1 more source

Planococcus maritimus ML1206 Isolated from Wild Oysters Enhances the Survival of Caenorhabditis elegans against Vibrio anguillarum

open access: yesMarine Drugs, 2021
With the widespread occurrence of aquaculture diseases and the broad application of antibiotics, drug-resistant pathogens have increasingly affected aquatic animals’ health.
Ying-Xiu Li   +7 more
doaj   +1 more source

The astacin protein family inCaenorhabditis elegans [PDF]

open access: yesEuropean Journal of Biochemistry, 2003
In the nematodeCaenorhabditis elegans, 40 genes code for astacin‐like proteins (nematode astacins, NAS). The astacins are metalloproteases present in bacteria, invertebrates and vertebrates and serve a variety of physiological functions like digestion, hatching, peptide processing, morphogenesis and pattern formation.
Moehrlen, F., Hutter, H., Zwilling, R.
openaire   +3 more sources

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

Genome-wide characterization, evolution, structure, and expression analysis of the F-box genes in Caenorhabditis

open access: yesBMC Genomics, 2021
Background F-box proteins represent a diverse class of adaptor proteins of the ubiquitin-proteasome system (UPS) that play critical roles in the cell cycle, signal transduction, and immune response by removing or modifying cellular regulators.
Ailan Wang, Wei Chen, Shiheng Tao
doaj   +1 more source

Protein interactome mapping in Caenorhabditis elegans

open access: yesCurrent Opinion in Systems Biology, 2019
The systematic identification of all protein-protein interactions that take place in an organism (the 'interactome') is an important goal in modern biology. The nematode Caenorhabditis elegans was one of the first multicellular models for which a proteome-wide interactome mapping project was initiated.
Remmelzwaal, Sanne, Boxem, Mike
openaire   +4 more sources

Caenorhabditis elegans sperm membrane protein interactome [PDF]

open access: yesBiology of Reproduction, 2018
The interaction and organization of proteins in the sperm membrane are important for all aspects of sperm function. We have determined the interactions between 12 known mutationally defined and cloned sperm membrane proteins in a model system for reproduction, the nematode Caenorhabditis elegans.
Marcello, Matthew R   +2 more
openaire   +2 more sources

Curcumin reduced fat accumulation in Caenorhabditis elegans

open access: yesCurrent Research in Food Science, 2021
Curcumin, the primary bioactive substance in turmeric, is known to be associated with weight loss. In this study, we employed Caenorhabditis elegans, a well-established in vivo nematode model to explore the role of curcumin in regulating lipid metabolism.
Yiren Yue   +3 more
doaj   +1 more source

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