Results 31 to 40 of about 1,677,918 (307)
A systematic analysis of protein palmitoylation in Caenorhabditis elegans [PDF]
BMC Genomics, 2014 Palmitoylation is a reversible post-translational protein modification which involves the addition of palmitate to cysteine residues. Palmitoylation is catalysed by the DHHC family of palmitoyl-acyl transferases (PATs) and reversibility is conferred by palmitoyl-protein thioesterases (PPTs).
Edmonds, Matthew J, Morgan, Alan
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Scientific Reports, 2021 Alzheimer disease (AD) is a neurodegenerative disorder with an –as of yet– unclear etiology and pathogenesis. Research to unveil disease processes underlying AD often relies on the use of neurodegenerative disease model organisms, such as Caenorhabditis ...
Avgi E. Apostolakou +4 more
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Ecotoxicology and Environmental Safety, 2021 The aim of this study was to identify Gα proteins mediating function of neuronal G protein-coupled receptors (GPCRs) in controlling the response to polystyrene nanoparticles (PS-NPs).
Yunhan Yang, Qiuli Wu, Dayong Wang
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Caenorhabditis elegans BAH-1 is a DUF23 protein expressed in seam cells and required for microbial biofilm binding to the cuticle. [PDF]
PLoS ONE, 2009 The cuticle of Caenorhabditis elegans, a complex, multi-layered extracellular matrix, is a major interface between the animal and its environment. Biofilms produced by the bacterial genus Yersinia attach to the cuticle of the worm, providing an assay for
Kevin Drace +2 more
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eLife, 2023 Argonaute (AGO) proteins associate with small RNAs to direct their effector function on complementary transcripts. The nematode Caenorhabditis elegans contains an expanded family of 19 functional AGO proteins, many of which have not been fully ...
Uri Seroussi +9 more
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Loss of secretory pathway FK506-binding proteins results in cold-sensitive lethality in caenorhabditis elegans [PDF]
, 2007 The FK506-binding proteins (FKBs) represent ubiquitous enzymes that catalyse the rate-limiting peptidyl prolyl cis-trans isomerization step in protein folding. The nematode <i>Caenorhabditis elegans</i> has eight FKBs, three of which (FKB-3, -
Page, Antony P. +7 more
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Bio-Protocol, 2022 Membraneless organelles, such as germ granules and stress granules, are liquid-like condensates formed by phase transition. Recently, we and others have adopted proximity-based labeling methods to determine the composition of these membraneless ...
Hannah Hertz, Ian Price, Wen Tang
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Auxin-mediated Protein Degradation in Caenorhabditis elegans
BIO-PROTOCOL, 2020 The auxin-inducible degron (AID) technology was recently adapted for use in the nematode Caenorhabditis elegans. Rapid degradation of C. elegans proteins tagged with an AID is mediated by a plant-specific F-box protein, transport inhibitor response 1 (TIR1), and occurs only in the presence of the phytohormone auxin.
Michael Martinez, David Matus
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Regulatory elements of Caenorhabditis elegans ribosomal protein genes [PDF]
BMC Genomics, 2012 Abstract Background Ribosomal protein genes (RPGs) are essential, tightly regulated, and highly expressed during embryonic development and cell growth. Even though their protein sequences are strongly conserved, their mechanism of regulation is not conserved across yeast, Drosophila, and vertebrates.
Sleumer Monica C +6 more
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Experimental considerations for study of C. elegans lysosomal proteins
G3: Genes, Genomes, Genetics, 2023 Lysosomes are an important organelle required for the degradation of a range of cellular components. Lysosome function is critical for development and homeostasis as dysfunction can lead to inherited genetic disorders, cancer, and neurodegenerative and ...
John C Clancy +5 more
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