Results 31 to 40 of about 73,600 (228)

RNAi targeting Caenorhabditis elegans α-arrestins has small or no effects on lifespan [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2017
Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization.
Sangsoon Park, Yoonji Jung, Seon Woo A. An, Heehwa G. Son, Wooseon Hwang, Dongyeop Lee, Murat Artan, Hae-Eun H. Park, Dae-Eun Jeong, Yujin Lee, Seung-Jae V. Lee   +10 more
doaj   +1 more source

Manganese disturbs metal and protein homeostasis in Caenorhabditis elegans [PDF]

Metallomics, 2014
Mn feeding induces altered metal composition and degrades protein homeostasis inC. elegans.
Suzanne, Angeli, Tracy, Barhydt, Ross, Jacobs, David W, Killilea, Gordon J, Lithgow, Julie K, Andersen   +5 more
openaire   +2 more sources

Changes of Protein Turnover in Aging Caenorhabditis elegans

Molecular & Cellular Proteomics, 2017
Protein turnover rates severely decline in aging organisms, including C. elegans However, limited information is available on turnover dynamics at the individual protein level during aging. We followed changes in protein turnover at one-day resolution using a multiple-pulse 15N-labeling and accurate mass spectrometry approach.
Ineke, Dhondt, Vladislav A, Petyuk, Sophie, Bauer, Heather M, Brewer, Richard D, Smith, Geert, Depuydt, Bart P, Braeckman   +6 more
openaire   +2 more sources

CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans.

PLoS ONE, 2019
Due to its ease of genetic manipulation and transparency, Caenorhabditis elegans (C. elegans) has become a preferred model system to study gene function by microscopy.
Brian J Thomas, Ira E Wight, Wendy Y Y Chou, Marco Moreno, Zachary Dawson, Arielle Homayouni, Huiyan Huang, Hyori Kim, Hanna Jia, Justin R Buland, Jennifer A Wambach, F Sessions Cole, Stephen C Pak, Gary A Silverman, Cliff J Luke   +14 more
doaj   +1 more source

RNAi targeting Caenorhabditis elegans α-arrestins has little effect on lifespan [version 4; referees: 2 approved, 1 approved with reservations]

F1000Research, 2017
Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization.
Sangsoon Park, Yoonji Jung, Seon Woo A. An, Heehwa G. Son, Wooseon Hwang, Dongyeop Lee, Murat Artan, Hae-Eun H. Park, Dae-Eun Jeong, Yujin Lee, Seung-Jae V. Lee   +10 more
doaj   +1 more source

The effect of ice-binding proteins on the cryopreservation of Caenorhabditis elegans

microPublication biology, 2023
Ice-binding proteins (IBPs) are capable of binding ice crystals and inhibiting their growth. IBPs have also been reported to stabilize cell membranes under non-freezing conditions. The effects of IBPs help to reduce cold- and freezing-induced damage to cells and tissues in cryopreservation.
Kuramochi, Masahiro, Arai, Tatsuya, Mio, Kazuhiro, Tsuda, Sakae, Sasaki, Yuji C   +4 more
openaire   +2 more sources

Neuronal calmodulin levels are controlled by CAMTA transcription factors

eLife, 2021
The ubiquitous Ca2+ sensor calmodulin (CaM) binds and regulates many proteins, including ion channels, CaM kinases, and calcineurin, according to Ca2+-CaM levels. What regulates neuronal CaM levels, is, however, unclear.
Thanh Thi Vuong-Brender, Sean Flynn, Yvonne Vallis, Saliha E Sönmez, Mario de Bono   +4 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

TbUNC119 and its binding protein complex are essential for propagation, motility, and morphogenesis of Trypanosoma brucei procyclic form cells. [PDF]

PLoS ONE, 2010
Flagellum-mediated motility of Trypanosoma brucei is considered to be essential for the parasite to complete stage development in the tsetse fly vector, while the mechanism by which flagellum-mediated motility is controlled are not fully understood.
Shigeru Ohshima, Mitsuko Ohashi-Suzuki, Yutaka Miura, Yoshisada Yabu, Noriko Okada, Nobuo Ohta, Takashi Suzuki   +6 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source