Results 31 to 40 of about 132,722 (276)

DAF-16/FoxO in Caenorhabditis elegans and its role in metabolic remodeling [PDF]

open access: yes, 2020
DAF-16, the only forkhead box transcription factors class O (FoxO) homolog in Caenorhabditis elegans, integrates signals from upstream pathways to elicit transcriptional changes in many genes involved in aging, development, stress, metabolism, and ...
Braeckman, Bart, Zečić, Aleksandra
core   +1 more source

A systematic analysis of protein palmitoylation in Caenorhabditis elegans [PDF]

open access: yesBMC Genomics, 2014
Palmitoylation is a reversible post-translational protein modification which involves the addition of palmitate to cysteine residues. Palmitoylation is catalysed by the DHHC family of palmitoyl-acyl transferases (PATs) and reversibility is conferred by palmitoyl-protein thioesterases (PPTs).
Edmonds, Matthew J, Morgan, Alan
openaire   +2 more sources

Exploring the conservation of Alzheimer-related pathways between H. sapiens and C. elegans: a network alignment approach

open access: yesScientific Reports, 2021
Alzheimer disease (AD) is a neurodegenerative disorder with an –as of yet– unclear etiology and pathogenesis. Research to unveil disease processes underlying AD often relies on the use of neurodegenerative disease model organisms, such as Caenorhabditis ...
Avgi E. Apostolakou   +4 more
doaj   +1 more source

Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the range of μg/L in C. elegans

open access: yesEcotoxicology and Environmental Safety, 2021
The aim of this study was to identify Gα proteins mediating function of neuronal G protein-coupled receptors (GPCRs) in controlling the response to polystyrene nanoparticles (PS-NPs).
Yunhan Yang, Qiuli Wu, Dayong Wang
doaj   +1 more source

Tubulins in C. elegans [PDF]

open access: yes, 2018
The C. elegans tubulin family is composed of nine α-, six β-, and one γ-tubulin. Tubulins are highly conserved, functioning as α-β heterodimers that assemble into microtubules.
Hurd, Daryl D.
core   +2 more sources

Caenorhabditis elegans BAH-1 is a DUF23 protein expressed in seam cells and required for microbial biofilm binding to the cuticle. [PDF]

open access: yesPLoS ONE, 2009
The cuticle of Caenorhabditis elegans, a complex, multi-layered extracellular matrix, is a major interface between the animal and its environment. Biofilms produced by the bacterial genus Yersinia attach to the cuticle of the worm, providing an assay for
Kevin Drace   +2 more
doaj   +1 more source

A comprehensive survey of C. elegans argonaute proteins reveals organism-wide gene regulatory networks and functions

open access: yeseLife, 2023
Argonaute (AGO) proteins associate with small RNAs to direct their effector function on complementary transcripts. The nematode Caenorhabditis elegans contains an expanded family of 19 functional AGO proteins, many of which have not been fully ...
Uri Seroussi   +9 more
doaj   +1 more source

The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes [PDF]

open access: yes, 2010
The cuticle of parasitic nematodes performs many critical functions and is essential for proper development and for protection from the host immune response.
Antony P. Page   +43 more
core   +1 more source

Visualization and Purification of Caenorhabditis elegans Germ Granule Proteins Using Proximity Labeling

open access: yesBio-Protocol, 2022
Membraneless organelles, such as germ granules and stress granules, are liquid-like condensates formed by phase transition. Recently, we and others have adopted proximity-based labeling methods to determine the composition of these membraneless ...
Hannah Hertz, Ian Price, Wen Tang
doaj   +1 more source

Immunofluorescent Localization of Proteins in Caenorhabditis elegans Muscle [PDF]

open access: yes, 2011
Caenorhabditis elegans is a premier model genetic system for discovering new information about the assembly and maintenance of striated muscle. The localization of a protein within a nematode muscle cell can reveal important clues to its function. In C.
Kristy J, Wilson   +2 more
openaire   +2 more sources

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