Biochemical analysis of Caenorhabditis elegans surface mutants [PDF]
, 1997 A collection of Caenorhabditis elegans mutants that show ectopic surface lectin binding (Srf mutants) was analyzed to determine the biochemical basis for this phenotype. This analysis involved selective removal or labeling of surface components, specific
Silverman, M., Link, C., Blaxter, M.L.
core
Characterization of the RhoGAP proteins RGA-3 and RGA-4 and the centrosomal protein SAS-5 in the early "Caenorhabditis elegans" embryo [PDF]
, 2007 The Caenorhabditis elegans embryo serves as a great tool to study cell biological processes like polarization and cell divison. The first cell division is unequal and cell polarization is dependant on the Rho GTPase regulated rearrangement of the cell ...
Schmutz, Cornelia
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Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Identification and characterization of agrin in "Caenorhabditis elegans" [PDF]
, 2006 Agrin is a large basement membrane (BM) proteoglycan expressed in many tissues in vertebrates, with particularly important function at the neuromuscular junction (NMJ) where it clusters acetylcholine receptors (AChRs) and maintains structural stability ...
Hrus, Ana
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"Caenorhabditis elegans" TEN-1 is essential for basement membrane function [PDF]
, 2008 Teneurins are large transmembrane proteins playing fundamental roles in development. They are highly expressed in the developing and adult nervous system in distinct layers, often in interconnected regions of the brain, where they were proposed to have ...
Trzebiatowska, Agnieszka
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ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Manganese disturbs metal and protein homeostasis in Caenorhabditis elegans [PDF]
Metallomics, 2014 Mn feeding induces altered metal composition and degrades protein homeostasis inC. elegans.
Suzanne, Angeli +5 more
openaire +2 more sources
The type II poly(A)-binding protein PABP-2 is a downstream target of the "let-7" microRNA in the heterochronic pathway of "Caenorhabditis elegans" : mechanisms of microRNA-mediated gene silencing in "Caenorhabditis elegans" [PDF]
, 2012 microRNAs (miRNAs) are a large class of small, non-coding RNAs that post-transcriptionally regulate gene expression in animals, plants and protozoa. miRNAs are genomically encoded and transcribed by RNA polymerase II. Primary transcripts are sequentially
Hurschler, Benjamin
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Optical Detection of Cellular Signals at Material Interfaces
Advanced Healthcare Materials, EarlyView.Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren +5 more
wiley +1 more source
Life cycle and population growth rate of Caenorhabditis elegans studied by a new method [PDF]
, 2009 Muschiol D, Schroeder F, Traunspurger W. Life cycle and population growth rate of Caenorhabditis elegans studied by a new method. BMC Ecology. 2009;9(1):14.Background: The free-living nematode Caenorhabditis elegans is the predominant model organism in ...
Schroeder Fabian +8 more
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