Results 1 to 10 of about 181,791 (317)
Morphogens function in concentration-dependent manners to instruct cell fate during tissue patterning. The cytoneme morphogen transport model posits that specialized filopodia extend between morphogen-sending and responding cells to ensure that ...
Eric T Hall +12 more
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The cytoskeleton–a composite network of biopolymers, molecular motors, and associated binding proteins–is a paradigmatic example of active matter. Particle transport through the cytoskeleton can range from anomalous and heterogeneous subdiffusion to ...
Janet Y. Sheung +6 more
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Myosin II motor proteins with different functions determine the fate of lamellipodia extension during cell spreading. [PDF]
Non-muscle cells express multiple myosin-II motor proteins myosin IIA, myosin IIB and myosin IIC transcribed from different loci in the human genome. Due to a significant homology in their sequences, these ubiquitously expressed myosin II motor proteins ...
Venkaiah Betapudi
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Contiguity and Structural Impacts of a Non-Myosin Protein within the Thick Filament Myosin Layers
Myosin dimers arranged in layers and interspersed with non-myosin densities have been described by cryo-EM 3D reconstruction of the thick filament in Lethocerus at 5.5 Å resolution.
Lynda M. Menard +2 more
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Secondary Structure of the Novel Myosin Binding Domain WYR and Implications within Myosin Structure
Structural changes in the myosin II light meromyosin (LMM) that influence thick filament mechanical properties and muscle function are modulated by LMM-binding proteins.
Lynda M. Menard +2 more
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Cardiovascular diseases are one of the leading causes of death in developing countries, generally originating as coronary artery disease (CAD) or hypertension. In later stages, many CAD patients develop left ventricle dysfunction (LVD).
Surendra Kumar +2 more
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Collective cell migration is central to many developmental and pathological processes. However, the mechanisms that keep cell collectives together and coordinate movement of multiple cells are poorly understood. Using the Drosophila border cell migration
Yujun Chen +9 more
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Expression of non-muscle type myosin heavy polypeptide 9 (MYH9) in mammalian cells
Myosin is a functional protein associated with cellular movement, cell division, muscle contraction and other functions. Members of the myosin super-family are distinguished from the myosin heavy chains that play crucial roles in cellular processes ...
T Takubo +6 more
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Diverse integrin adhesion stoichiometries caused by varied actomyosin activity [PDF]
Cells in an organism are subjected to numerous sources of external and internal forces, and are able to sense and respond to these forces. Integrin-mediated adhesion links the extracellular matrix outside cells to the cytoskeleton inside, and ...
Natalia A. Bulgakova +2 more
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Myosin XVI in the Nervous System
The myosin family is a large inventory of actin-associated motor proteins that participate in a diverse array of cellular functions. Several myosin classes are expressed in neural cells and play important roles in neural functioning.
Elek Telek +2 more
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