Results 1 to 10 of about 282,889 (299)

Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex

open access: yeseLife, 2021
Morphogens function in concentration-dependent manners to instruct cell fate during tissue patterning. The cytoneme morphogen transport model posits that specialized filopodia extend between morphogen-sending and responding cells to ensure that ...
Eric T Hall   +12 more
doaj   +1 more source

Motor-driven advection competes with crowding to drive spatiotemporally heterogeneous transport in cytoskeleton composites

open access: yesFrontiers in Physics, 2022
The cytoskeleton–a composite network of biopolymers, molecular motors, and associated binding proteins–is a paradigmatic example of active matter. Particle transport through the cytoskeleton can range from anomalous and heterogeneous subdiffusion to ...
Janet Y. Sheung   +6 more
doaj   +1 more source

Myosin II motor proteins with different functions determine the fate of lamellipodia extension during cell spreading. [PDF]

open access: yesPLoS ONE, 2010
Non-muscle cells express multiple myosin-II motor proteins myosin IIA, myosin IIB and myosin IIC transcribed from different loci in the human genome. Due to a significant homology in their sequences, these ubiquitously expressed myosin II motor proteins ...
Venkaiah Betapudi
doaj   +1 more source

Contiguity and Structural Impacts of a Non-Myosin Protein within the Thick Filament Myosin Layers

open access: yesBiology, 2021
Myosin dimers arranged in layers and interspersed with non-myosin densities have been described by cryo-EM 3D reconstruction of the thick filament in Lethocerus at 5.5 Å resolution.
Lynda M. Menard   +2 more
doaj   +1 more source

Stratification relieves constraints from steric hindrance in the generation of compact acto-myosin asters at the membrane cortex [PDF]

open access: yes, 2020
Recent in-vivo studies have revealed that several membrane proteins are driven to form nanoclusters by active contractile flows arising from F-actin and myosin at the cortex. The mechanism of clustering was shown to be arising from the dynamic patterning
Bhat, Abrar   +5 more
core   +3 more sources

Secondary Structure of the Novel Myosin Binding Domain WYR and Implications within Myosin Structure

open access: yesBiology, 2021
Structural changes in the myosin II light meromyosin (LMM) that influence thick filament mechanical properties and muscle function are modulated by LMM-binding proteins.
Lynda M. Menard   +2 more
doaj   +1 more source

Sarcomeric Gene Variants and Their Role with Left Ventricular Dysfunction in Background of Coronary Artery Disease

open access: yesBiomolecules, 2020
Cardiovascular diseases are one of the leading causes of death in developing countries, generally originating as coronary artery disease (CAD) or hypertension. In later stages, many CAD patients develop left ventricle dysfunction (LVD).
Surendra Kumar   +2 more
doaj   +1 more source

Protein phosphatase 1 activity controls a balance between collective and single cell modes of migration

open access: yeseLife, 2020
Collective cell migration is central to many developmental and pathological processes. However, the mechanisms that keep cell collectives together and coordinate movement of multiple cells are poorly understood. Using the Drosophila border cell migration
Yujun Chen   +9 more
doaj   +1 more source

Expression of non-muscle type myosin heavy polypeptide 9 (MYH9) in mammalian cells

open access: yesEuropean Journal of Histochemistry, 2009
Myosin is a functional protein associated with cellular movement, cell division, muscle contraction and other functions. Members of the myosin super-family are distinguished from the myosin heavy chains that play crucial roles in cellular processes ...
T Takubo   +6 more
doaj   +1 more source

The coagulation of myosin in muscle [PDF]

open access: yes, 1937
The coagulation of myosin is one of the few changes in the proteins of muscle known to take place during contraction and rigor. Although under certain conditions as much as one-third of the total protein of muscle may become insoluble, the significance ...
Mirsky, A. E.
core   +2 more sources

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