HLH-1 Modulates Muscle Proteostasis During Caenorhabditis elegans Larval Development
Frontiers in Cell and Developmental Biology, 2022 Muscle proteostasis is shaped by the myogenic transcription factor MyoD which regulates the expression of chaperones during muscle differentiation. Whether MyoD can also modulate chaperone expression in terminally differentiated muscle cells remains open.
Khairun Nisaa, Anat Ben-Zvi
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Differential expression of skeletal muscle genes following administration of clenbuterol to exercised horses. [PDF]
, 2016 BackgroundClenbuterol, a beta2-adrenergic receptor agonist, is used therapeutically to treat respiratory conditions in the horse. However, by virtue of its mechanism of action it has been suggested that clenbuterol may also have repartitioning affects in
Chouicha, Nadira +4 more
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Zebrafish as a Model for the Study of Live in vivo Processive Transport in Neurons
Frontiers in Cell and Developmental Biology, 2019 Motor proteins are responsible for transport of vesicles and organelles within the cell cytoplasm. They interact with the actin cytoskeleton and with microtubules to ensure communication and supply throughout the cell.
Valérie Bercier +4 more
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MicroRNA Regulatory Pathways in the Control of the Actin–Myosin Cytoskeleton
Cells, 2020 MicroRNAs (miRNAs) are key modulators of post-transcriptional gene regulation in a plethora of processes, including actin–myosin cytoskeleton dynamics.
Karen Uray, Evelin Major, Beata Lontay
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RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
MYO, a Candidate Gene for Haploid Induction in Maize Causes Male Sterility
Plants, 2020 Doubled haploid technology is highly successful in maize breeding programs and is contingent on the ability of maize inducers to efficiently produce haploids.
Kimberly Vanous +3 more
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Measurement of junctional tension in epithelial cells at the onset of primitive streak formation in the chick embryo via non-destructive optical manipulation [PDF]
, 2020 Directional cell intercalations of epithelial cells during gastrulation has in several organisms been shown to be associated with a planar cell polarity in the organisation of the actin-myosin cytoskeleton and is postulated to reflect directional tension
Antin +39 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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Uncoupling apical constriction from tissue invagination
eLife, 2017 Apical constriction is a widely utilized cell shape change linked to folding, bending and invagination of polarized epithelia. It remains unclear how apical constriction is regulated spatiotemporally during tissue invagination and how this cellular ...
SeYeon Chung +2 more
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Discovery of Viral Myosin Genes With Complex Evolutionary History Within Plankton
Frontiers in Microbiology, 2021 Nucleocytoplasmic large DNA viruses (NCLDVs) infect diverse eukaryotes and form a group of viruses with capsids encapsulating large genomes. Recent studies are increasingly revealing a spectacular array of functions encoded in their genomes, including ...
Soichiro Kijima +6 more
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