Mechanisms in the pathogenesis of poststroke spasticity
Objective: to study the mechanisms of poststroke spasticity and the role of structural and functional impairments of skeletal muscles in its pathogenesis. Patients and methods.
E. A. Katushkina +3 more
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The fundamental basis of muscle contraction ‘the sliding filament model’ (Huxley and Niedergerke, 1954; Huxley and Hanson, 1954) and the ‘swinging, tilting crossbridge-sliding filament mechanism’ (Huxley, 1969; Huxley and Brown, 1967) nucleated a field ...
Manuel Schmid, Christopher N. Toepfer
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A small-molecule inhibitor of T. gondii motility induces the posttranslational modification of myosin light chain-1 and inhibits myosin motor activity [PDF]
Toxoplasma gondii is an obligate intracellular parasite that enters cells by a process of active penetration. Host cell penetration and parasite motility are driven by a myosin motor complex consisting of four known proteins: TgMyoA, an unconventional ...
Carey, Kimberly L. +15 more
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The invasion of the erythrocyte by Plasmodium falciparum depends on the ability of the merozoite to move through the membrane invagination. This ability is probably mediated by actin dependent motors.
Claudia Forero, Moisés Wasserman
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Breaking the clip for cargo unloading from motor proteins: mechanism and significance
The mitochondrion is an essential organelle involved in ATP generation, lipid metabolism, regulation of calci- um ions, etc. Therefore, it should be inherited properly by newly generated cells.
Keisuke Obara, Takumi Kamura
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Fluorescent probes of the orientation of myosin regulatory light chains in relaxed, rigor, and contracting muscle. [PDF]
The orientation of the light-chain region of myosin heads in relaxed, rigor, and isometrically contracting fibers from rabbit psoas muscle was studied by fluorescence polarization. Cysteine 108 of chicken gizzard myosin regulatory light chain (cgRLC) was
Shrimpton, C. +10 more
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Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells [PDF]
© The Authors, 2009 . This article is distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. The definitive version was published in Journal of Cell Biology 186 (2009): 727-738, doi:10.1083/jcb ...
Vale, Ronald D. +5 more
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Mitochondrial transport in neurons and evidence for its involvement in acute neurological disorders
Ensuring mitochondrial quality is essential for maintaining neuronal homeostasis, and mitochondrial transport plays a vital role in mitochondrial quality control.
Dengfeng Lu +8 more
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Single molecule mechanics resolves the earliest events in force generation by cardiac myosin
Key steps of cardiac mechanochemistry, including the force-generating working stroke and the release of phosphate (Pi), occur rapidly after myosin-actin attachment.
Michael S Woody +4 more
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Type-I myosins promote actin polymerization to drive membrane bending in endocytosis
Clathrin-mediated endocytosis in budding yeast requires the formation of a dynamic actin network that produces the force to invaginate the plasma membrane against the intracellular turgor pressure.
Hetty E Manenschijn +5 more
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