Results 31 to 40 of about 282,889 (299)

Single molecule mechanics resolves the earliest events in force generation by cardiac myosin

eLife, 2019
Key steps of cardiac mechanochemistry, including the force-generating working stroke and the release of phosphate (Pi), occur rapidly after myosin-actin attachment.
Michael S Woody, Donald A Winkelmann, Marco Capitanio, E Michael Ostap, Yale E Goldman   +4 more
doaj   +1 more source

Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. [PDF]

, 2013
Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results from an alternative start of transcription of the Myo1c gene adding an extra 16 amino acids at ...
A Bose, A Bose, A Obrdlik, Alexander Bohla, Ali Önder Yildirim, Alžběta Kalendová, AM Sokac, Andre Van Wijnen, B Barylko, Birgit Rathkolb, C Ambrosino, C Zadro, CH Chuang, D Schenten, DN Simon, E Arif, EA Stauffer, Eckhard Wolf, F Aslinia, FS Wang, G Nowak, H Fuchs, Helmut Fuchs, I Grummt, I Ihnatovych, J Ye, Jana Rohožková, K Fulzele, K Kysela, KA McGowan, L Pestic-Dragovich, M Ferron, M Kahle, Martin Hrabě de Angelis, MC Wagner, Michal Kahle, N Fomproix, O Reizes, Oliver Eickelberg, P Leneuve, P Percipalle, Pavel Hozák, PG Gillespie, PG Gillespie, R Dzijak, R Nambiar, Rastislav Dzijak, RE McConnell, Thomas Rülicke, TJ Diefenbach, TN Willig, Tobias Stoeger, Tomáš Venit, V Gailus-Durner, Valérie Gailus-Durner, Volker Schmidt, VV Philimonenko, VV Philimonenko, WA Hofmann, Wolfgang Hans   +59 more
core   +5 more sources

Type-I myosins promote actin polymerization to drive membrane bending in endocytosis

eLife, 2019
Clathrin-mediated endocytosis in budding yeast requires the formation of a dynamic actin network that produces the force to invaginate the plasma membrane against the intracellular turgor pressure.
Hetty E Manenschijn, Andrea Picco, Markus Mund, Anne-Sophie Rivier-Cordey, Jonas Ries, Marko Kaksonen   +5 more
doaj   +1 more source

Changes in Myosin from Silver Carp (Hypophthalmichthys molitrix) under Microwave-Assisted Water Bath Heating on a Multiscale

Foods, 2022
To further prove the advantages of microwave-assisted water bath heating (MWH) in low-value fish processing, the effects of different heating methods (two heating stage method, high temperature section respectively using MWH1, MWH2, MWH3, WH—water ...
Haihua Cong, He Lyu, Wenwen Liang, Ziwei Zhang, Xiaodong Chen   +4 more
doaj   +1 more source

Mammalian Myosin-18A, a Highly Divergent Myosin [PDF]

Journal of Biological Chemistry, 2013
The Mus musculus myosin-18A gene is expressed as two alternatively spliced isoforms, α and β, with reported roles in Golgi localization, in maintenance of cytoskeleton, and as receptors for immunological surfactant proteins. Both myosin-18A isoforms feature a myosin motor domain, a single predicted IQ motif, and a long coiled-coil reminiscent of myosin-
Stephanie, Guzik-Lendrum, Sarah M, Heissler, Neil, Billington, Yasuharu, Takagi, Yi, Yang, Peter J, Knight, Earl, Homsher, James R, Sellers   +7 more
openaire   +2 more sources

Movement Asymmetries: From Their Molecular Origin to the Analysis of Movement Asymmetries in Athletes

Life, 2023
Asymmetry plays a major role in biology at all scales. This can be seen in the helix of DNA, the fact that the human heart is on the left side, or that most people use their right hand.
Alexander Egoyan, Giorgi Parulava, Steven Baker, Melinda Gilhen-Baker, Giovanni N. Roviello   +4 more
doaj   +1 more source

Spatial fluctuations at vertices of epithelial layers: quantification of regulation by Rho pathway [PDF]

, 2018
In living matter, shape fluctuations induced by acto-myosin are usually studied in vitro via reconstituted gels, whose properties are controlled by changing the concentrations of actin, myosin and cross-linkers.
Comelles, J., Fodor, É., Gov, N. S., Mehandia, V., Riveline, D., Thiagarajan, R., van Wijland, F., Visco, P.   +7 more
core   +1 more source

F-actin and myosin F control apicoplast elongation dynamics which drive apicoplast-centrosome association in Toxoplasma gondii

mBio, 2023
Toxoplasma gondii contains an essential plastid organelle called the apicoplast that is necessary for fatty acid, isoprenoid, and heme synthesis. Perturbations affecting apicoplast function or inheritance lead to parasite death.
Parvathi Madhavi Devarakonda, Valeria Sarmiento, Aoife T. Heaslip   +2 more
doaj   +1 more source

Quantum dot-based thermometry uncovers decreased myosin efficiency in an experimental intensive care unit model

Frontiers in Physiology
Critical illness myopathy (CIM) detrimentally affects muscle function in ICU patients, with a dramatic loss of muscle mass and function where the loss in specific force exceeds the loss in muscle mass (maximum force normalized to muscle cross-sectional ...
Meishan Li, Meishan Li, Nicola Cacciani, Nicola Cacciani, Fernando Ribeiro, Fernando Ribeiro, Fernando Ribeiro, Yvette Hedström, Yvette Hedström, Bhanu P. Jena, Bhanu P. Jena, Lars Larsson, Lars Larsson, Lars Larsson   +13 more
doaj   +1 more source

Estudo de mutações causadoras de cardiomiopatia hipertrófica em um grupo de pacientes no Espírito Santo, Brasil Estudio de mutaciones causadoras de cardiomiopatía hipertrófica en un grupo de pacientes en Espírito Santo, Brasil Study of mutations causing hypertrophic cardiomyopathy in a group of patients from Espirito Santo, Brazil

Arquivos Brasileiros de Cardiologia, 2010
FUNDAMENTO: A cardiomiopatia hipertrófica (CH) é a doença cardíaca hereditária mais frequente, causada por mutações nos genes codificadores para proteínas do sarcômero. Embora mais de 430 mutações tenham sido identificadas em vários continentes e países,
Júlia Daher Carneiro Marsiglia, Maria do Carmo Pimentel Batitucci, Flávia de Paula, Clara Barbirato, Edmundo Arteaga, Aloir Queiroz de Araújo   +5 more
doaj   +1 more source