The role of myosin II in stabilizing actin tethers promoting GLUT4 exocytosis in 3T3-L1 adipocytes [PDF]
Aberrant insulin signaling results in an impaired ability to clear glucose from the bloodstream, which progresses to type II diabetes mellitus once insulin stimulation no longer results in a significant decrease in blood glucose levels.
Nikouyeh, Jonah B. +1 more
core
Modification of Loop 1 Affects the Nucleotide Binding Properties of Myo1c, the Adaptation Motor in the Inner Ear [PDF]
Myo1c is one of eight members of the mammalian myosin I family of actin-associated molecular motors. In stereocilia of the hair cells in the inner ear, Myo1c presumably serves as the adaptation motor, which regulates the opening and closing of ...
Adamek, Nancy +3 more
core +1 more source
Localization of Myosin II and identification of its potential upstream regulators in Dictyostelium discoideum [PDF]
The thesis work presented here aimed to understand how myosin II is regulated in Dictyostelium discoideum within the context of chemotactic signaling and cell migration.
Herring, Ashley +1 more
core
Relative affinity constants by electrospray ionization and Fourier transform ion cyclotron resonance mass spectrometry: calmodulin binding to peptide analogs of myosin light chain kinase [PDF]
Synthetic RS20 peptide and a set of its point-mutated peptide analogs have been used to analyze the interactions between calmodulin (CaM) and the CaM-binding sequence of smooth-muscle myosin light chain kinase both in the presence and the absence of Ca2+.
Lafitte, Daniel +3 more
core +1 more source
Myosin VI Rewrites the Rules for Myosin Motors [PDF]
Myosin VI is the only type of myosin motor known to move toward the minus ends of actin filaments. This reversal in the direction of its movement is in part a consequence of the repositioning of its lever arm. In addition, myosin VI has a number of other specialized structural and functional adaptations that optimize performance of its unique cellular ...
Sweeney, H. Lee, Houdusse, Anne
openaire +2 more sources
Investigating the role of nuclear myosin I in the low serum induced repositioning of chromosome 10 in interphase nuclei [PDF]
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.The nucleus of mammalian cells has been proven to be highly organised.
Amira, Manelle
core
Determination of the Maximum Velocity of Filaments in the in vitro Motility Assay
The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders.
Nasrin Bopp +4 more
doaj +1 more source
Rab11A-controlled assembly of the inner membrane complex is required for completion of apicomplexan cytokinesis [PDF]
The final step during cell division is the separation of daughter cells, a process that requires the coordinated delivery and assembly of new membrane to the cleavage furrow.
Manuel Rauch +31 more
core +1 more source
The participation of cell adhesion molecules (CAMs) in the establishment of autoimmune and infectious myocarditis is an important matter of investigation and may have therapeutic implication. Trypanosoma cruzi infection induces a CD8-mediated myocarditis
Ana Paula MP Marino +2 more
doaj +1 more source
Myosin-II localizes to the cell cortex when cells are confined within microfluidic gradient channels. [PDF]
(A) Fluorescence intensity of GFP-myosin was higher at the cell cortex (Icort) than in the cytosol (Icyto). (B) The ratio of Icort/Icyto increased when the microfluidic confinement channel height was decreased from 3.8 μm to 1.7 μm.
Zachary R. Gagnon (3196320) +3 more
core +1 more source

