Results 61 to 70 of about 181,791 (317)
, 2014 This work was supported by US Public Health Service grant AI054961 (GEW/NJW), a University Research Fellowship from the Royal Society (NJW) and funding for the mass spectrometry analysis was provided by the Vermont Genetics Network/NIH Grant 8P20GM103449
Pathak, R.B. +23 more
core +1 more source
Topography‐Regulated Screening Platform for Myoblast Contact Guidance
Advanced Materials Technologies, EarlyView.This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng +6 more
wiley +1 more source
The role of myosin II in stabilizing actin tethers promoting GLUT4 exocytosis in 3T3-L1 adipocytes [PDF]
, 2018 Aberrant insulin signaling results in an impaired ability to clear glucose from the bloodstream, which progresses to type II diabetes mellitus once insulin stimulation no longer results in a significant decrease in blood glucose levels.
Nikouyeh, Jonah B. +1 more
core
, 2018 (A) Low-density, two-day cell cultures on collagen stained for F-actin (green), phospho-myosin (pMLC, red) and DNA (blue), and single channel images for F-actin, and for phospho-myosin (pMLC).
Angela I. M. Barth (5844509) +2 more
core +1 more source
Modification of Loop 1 Affects the Nucleotide Binding Properties of Myo1c, the Adaptation Motor in the Inner Ear [PDF]
, 2010 Myo1c is one of eight members of the mammalian myosin I family of actin-associated molecular motors. In stereocilia of the hair cells in the inner ear, Myo1c presumably serves as the adaptation motor, which regulates the opening and closing of ...
Adamek, Nancy +3 more
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Advanced Materials Technologies, EarlyView.We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger +9 more
wiley +1 more source
Localization of Myosin II and identification of its potential upstream regulators in Dictyostelium discoideum [PDF]
, 2015 The thesis work presented here aimed to understand how myosin II is regulated in Dictyostelium discoideum within the context of chemotactic signaling and cell migration.
Herring, Ashley +1 more
core
Myosin-II and cytosolic mCherry during migration under microfluidic confinement.
, 2016 (A) Myosin-II accumulates at the cortex in confined Dictyostelium cells, while (B) mCherry, used as a volume marker, does not show cortical/membrane enrichment at 1.7 μm.
Zachary R. Gagnon (3196320) +3 more
core +1 more source
Relative affinity constants by electrospray ionization and Fourier transform ion cyclotron resonance mass spectrometry: calmodulin binding to peptide analogs of myosin light chain kinase [PDF]
, 2003 Synthetic RS20 peptide and a set of its point-mutated peptide analogs have been used to analyze the interactions between calmodulin (CaM) and the CaM-binding sequence of smooth-muscle myosin light chain kinase both in the presence and the absence of Ca2+.
Lafitte, Daniel +3 more
core +1 more source
Myosin VI Rewrites the Rules for Myosin Motors [PDF]
Cell, 2010 Myosin VI is the only type of myosin motor known to move toward the minus ends of actin filaments. This reversal in the direction of its movement is in part a consequence of the repositioning of its lever arm. In addition, myosin VI has a number of other specialized structural and functional adaptations that optimize performance of its unique cellular ...
Sweeney, H. Lee, Houdusse, Anne
openaire +2 more sources