Results 81 to 90 of about 282,889 (299)

Myosin [PDF]

The Journal of General Physiology, 1967
There is fairly general agreement that myosin isolated from rabbit skeletal muscle has a molecular weight of about 500,000. The higher values that have been reported apparently reflect protein aggregation related to the method of preparation. On the basis of present evidence, the myosin molecule has an elongate helical core of two f subunits (average ...
Paul Dreizen, Lewis C. Gershman, Paul P. Trotta, Alfred Stracher   +3 more
openaire   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Determination of the Maximum Velocity of Filaments in the in vitro Motility Assay

Frontiers in Physiology, 2019
The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders.
Nasrin Bopp, Nasrin Bopp, Lisa-Mareike Scheid, Rainer H. A. Fink, Karl Rohr   +4 more
doaj   +1 more source

Topography‐Regulated Screening Platform for Myoblast Contact Guidance

Advanced Materials Technologies, EarlyView.
This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng, Torben A.B. van der Boon, Savannah Amy Haupt, Adam Jones, Yanjing Ji, Theo G. Van Kooten, Patrick van Rijn   +6 more
wiley   +1 more source

Differential expression of adhesion moleculesshaping the T-cell subset prevalence during the early phase of autoimmune and Trypanosoma cruzi-elicited myocarditis

Memorias do Instituto Oswaldo Cruz, 2003
The participation of cell adhesion molecules (CAMs) in the establishment of autoimmune and infectious myocarditis is an important matter of investigation and may have therapeutic implication. Trypanosoma cruzi infection induces a CD8-mediated myocarditis
Ana Paula MP Marino, Maria Inês P Azevedo, Joseli Lannes-Vieira   +2 more
doaj   +1 more source

Age- and activity-related differences in the abundance of Myosin essential and regulatory light chains in human muscle [PDF]

, 2016
Traditional methods for phenotyping skeletal muscle (e.g., immunohistochemistry) are labor-intensive and ill-suited to multixplex analysis, i.e., assays must be performed in a series. Addressing these concerns represents a largely unmet research need but
Burniston, Jatin G., Close, Graeme L., Cobley, James N., Edwards, Ben J., Malik, Zulezwan Ab., Morton, James P.   +5 more
core   +4 more sources

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Molecular mechanisms of the regulation of ATPase cycle in striated muscle [PDF]

, 2007
New data on the molecular mechanism of the regulation of ATPase cycle by troponin-tropomyosin system have been obtained in reconstructed muscle fibers by using the polarized fluorescence technique, which allowed us following the azimuthal movements of ...
Charles S. Redwood, Olga E. Karpicheva, Yuri S. Borovikov   +2 more
core   +1 more source

Possible origins of macroscopic left-right asymmetry in organisms

, 2012
I consider the microscopic mechanisms by which a particular left-right (L/R) asymmetry is generated at the organism level from the microscopic handedness of cytoskeletal molecules.
A. Tamada, A. Varma, A. Vilfan, A.M. Heacock, A.R. Palmer, C. Ambrose, C. Arrieumerlou, C. McManus, C. Pohl, C.H. Wiggins, C.L. Henley, C.R. Cowan, C.S. Peskin, C.W. Wolgemuth, Christopher L. Henley, D. Vavylonis, D.S. Adams, D.W. Ehrhardt, E. Ben-Jacob, E. Ben-Jacob, E. Kawamura, E.C. Eren, E.C. Eren, E.E. Deinum, F. Ziebert, F.C. Frank, G. Salbreux, G.M. Grason, G.O. Wasteneys, H. Hamada, H.F. Romijn, I. Mabuchi, J. Chan, J. Chan, J. Cooke, J. Gore, J. Hagmann, J. Salje, J. Xu, J.A. Åström, J.F. Allard, J.F. Allard, J.F. Beausang, J.H.E. Cartwright, K. Taniguchi, L.F. Jones, L.Q. Wan, M. Levin, M. Levin, M. Levin, M. Mayer, M.E. Halpern, M.L. Manning, M.P. Wold, M.V. Danilchik, M.V. Thompson, M.Y. Ali, N. Hirokawa, N. Morone, N.A. Brown, N.H. Mendelson, N.H. Mendelson, P. Spéder, P. Spéder, R. Dixit, R. Kawamura, R. Kuroda, R.D. Kamien, R.D. Preston, R.J. Hawkins, R.J. Poole, R.M. Figge, S. Aw, S. Hozumi, S. Nonaka, S. Nonaka, S. Thitamadee, S. Wang, S.H. Tindemans, S.L. Shaw, S.S. Andrews, T. Hashimoto, T. Ishida, T. Kamasaki, T. Lionnet, T. Nishizaka, T. Okumura, T. Sun, T.-H. Chuan, V.A. Avertisov, V.A. Baulin, W. Lauga, W.B. Wood, W.B. Wood, W.B. Wood, W.R. DiLuzio, X.-Q. Shi, Y. Nakadera, Y. Shibazaki, Y. Wu, Y.B. Malashichev   +100 more
core   +1 more source

Light‐Driven Quadrupedal Walking Biohybrid Robot With Antagonistic Muscle‐Rings and Inclined Joints

Advanced Robotics Research, EarlyView.
This work presents a light‐driven quadrupedal walking biohybrid robot powered by antagonistic muscle‐rings that achieve alternating walking gait. Optical training improved reproducibility of cultured muscle tissues, while caffeine treatment enhanced contractile force.
Shotaro Saito, Byeongwook Jo, Tomohiro Morita, Shota Noda, Minghao Nie, Shoji Takeuchi   +5 more
wiley   +1 more source