Results 71 to 80 of about 73,600 (228)

Evolutionary Dynamics of the SKN-1 → MED → END-1,3 Regulatory Gene Cascade in Caenorhabditis Endoderm Specification

G3: Genes, Genomes, Genetics, 2020
Gene regulatory networks and their evolution are important in the study of animal development. In the nematode, Caenorhabditis elegans, the endoderm (gut) is generated from a single embryonic precursor, E.
Morris F. Maduro
doaj   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

A multi-domain snail metallothionein increases cadmium resistance and fitness in Caenorhabditis elegans

Scientific Reports
Metallothioneins (MTs) are a family of mostly low-molecular weight, cysteine-rich proteins capable of specific metal-ion binding that are involved in metal detoxification and homeostasis, as well as in stress response.
Andreas Andric, Michael Niederwanger, Eva Albertini, Pidder Jansen-Dürr, Stephen R. Stürzenbaum, Reinhard Dallinger, Veronika Pedrini-Martha, Alexander K. H. Weiss   +7 more
doaj   +1 more source

nGASP – the nematode genome annotation assessment project

BMC Bioinformatics, 2008
Background While the C. elegans genome is extensively annotated, relatively little information is available for other Caenorhabditis species. The nematode genome annotation assessment project (nGASP) was launched to objectively assess the accuracy of ...
Harris Todd W, Flicek Paul, McKay Sheldon J, Fiedler Tristan J, Coghlan Avril, Blasiar Darin, Stein Lincoln D   +6 more
doaj   +1 more source

Ginseng Extract Ameliorates the Negative Physiological Effects of Heat Stress by Supporting Heat Shock Response and Improving Intestinal Barrier Integrity: Evidence from Studies with Heat-Stressed Caco-2 Cells, C. elegans and Growing Broilers

Molecules, 2020
Climatic changes and heat stress have become a great challenge in the livestock industry, negatively affecting, in particular, poultry feed intake and intestinal barrier malfunction.
Georg Sandner, Andreas S. Mueller, Xiaodan Zhou, Verena Stadlbauer, Bettina Schwarzinger, Clemens Schwarzinger, Uwe Wenzel, Klaus Maenner, Jan Dirk van der Klis, Stefan Hirtenlehner, Tobias Aumiller, Julian Weghuber   +11 more
doaj   +1 more source

High atmospheric pressure rescues plant growth under humidity stress: A model for climate‐resilient deep underground agriculture

Deep Underground Science and Engineering, EarlyView.
High atmospheric pressure (120 kPa) in deep underground counteracts humidity‐induced physiological stress in plants, stabilizing water balance and enhancing antioxidative defenses. This synergy boosts biomass despite elevated humidity, demonstrating sustainable deep underground agriculture potential under climate uncertainty.
Yuxin He, Linglu Xu, Xiao Tan, Wenhua Zhuang, Naiwen Li, Chao Liu, Bo Tan   +6 more
wiley   +1 more source

Revelations from the Nematode Caenorhabditis elegans on the Complex Interplay of Metal Toxicological Mechanisms

Journal of Toxicology, 2011
Metals have been definitively linked to a number of disease states. Due to the widespread existence of metals in our environment from both natural and anthropogenic sources, understanding the mechanisms of their cellular detoxification is of upmost ...
Ebany J. Martinez-Finley, Michael Aschner   +1 more
doaj   +1 more source

Single‐cell sequencing reveals potential novel insights into appendage‐patterning and joint‐development in a spider

Developmental Dynamics, EarlyView.
Abstract Background Jointed appendages represent one of the key innovations of arthropods, and thus understanding the development and evolution of these structures is important for the understanding of the evolutionary success of Arthropoda. In this paper, we analyze a cell cluster that was identified in a previous single‐cell sequencing (SCS ...
Brenda I. Medina‐Jiménez, Graham E. Budd, Ralf Janssen   +2 more
wiley   +1 more source

OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development.

PLoS Biology, 2008
Notch signaling is critical for cell fate decisions during development. Caenorhabditis elegans and vertebrate Notch ligands are more diverse than classical Drosophila Notch ligands, suggesting possible functional complexities.
Hidetoshi Komatsu, Michael Y Chao, Jonah Larkins-Ford, Mark E Corkins, Gerard A Somers, Tim Tucey, Heather M Dionne, Jamie Q White, Khursheed Wani, Mike Boxem, Anne C Hart   +10 more
doaj   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source