Results 81 to 90 of about 132,722 (276)

Preparation, Component Identification, and Antioxidant Activity of Anthocyanins From Punica granatum “Tunisia”

AgriFood: Journal of Agricultural Products for Food, EarlyView.
The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang, Xu‐han Yang, Meng‐qi Zhang, Xu Guo, Ning‐yang Li, Fang‐yu Long, Chao Liu   +6 more
wiley   +1 more source

Copper Homeostasis in the Model Organism C. elegans

Cells
Cellular and organismic copper (Cu) homeostasis is regulated by Cu transporters and Cu chaperones to ensure the controlled uptake, distribution and export of Cu ions.
Verena Alexia Ohse, Lars-Oliver Klotz, Josephine Priebs   +2 more
doaj   +1 more source

The role of RNA-binding proteins in orchestrating germline development in Caenorhabditis elegans

Frontiers in Cell and Developmental Biology, 2023
RNA passed from parents to progeny controls several aspects of early development. The germline of the free-living nematode Caenorhabditis elegans contains many families of evolutionarily conserved RNA-binding proteins (RBPs) that target the untranslated ...
Mennatallah M. Y. Albarqi, Sean P. Ryder
doaj   +1 more source

Caenorhabditis elegansIntersectin: A Synaptic Protein Regulating Neurotransmission [PDF]

Molecular Biology of the Cell, 2007
Intersectin is a multifunctional protein that interacts with components of the endocytic and exocytic pathways, and it is also involved in the control of actin dynamics. Drosophila intersectin is required for viability, synaptic development, and synaptic vesicle recycling.
S. Rose, M.G. Malabarba, C. Krag, A. Schultz, H. Tsushima, P.P. Di Fiore, A. E. Salcini   +6 more
openaire   +4 more sources

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

Advanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu, Rujia Liu, Xinyan Zhang, Xun Chen, Shuhua Yue   +4 more
wiley   +1 more source

An Activating Mutation in sos-1 Identifies Its Dbl Domain as a Critical Inhibitor of the Epidermal Growth Factor Receptor Pathway during Caenorhabditis elegans Vulval Development [PDF]

, 2007
Proper regulation of receptor tyrosine kinase (RTK)-Ras-mitogen-activated protein kinase (MAPK) signaling pathways is critical for normal development and the prevention of cancer.
Elgort, Marc G., Huang, Jingyu, Jongeward, Gregg, Lauritzen, Amara, Modzelewska, Katarzyna, Moghal, Nadeem, Sternberg, Paul W., Yoon, Charles H.   +7 more
core   +2 more sources

Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases

Disease Models & Mechanisms, 2014
Caenorhabditis elegans has a number of distinct advantages that are useful for understanding the basis for cellular and organismal dysfunction underlying age-associated diseases of protein misfolding.
Carmen I. Nussbaum-Krammer, Richard I. Morimoto   +1 more
doaj   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

The Caenorhabditis elegans proteome response to two protective Pseudomonas symbionts

mBio
The Caenorhabditis elegans natural microbiota isolates Pseudomonas lurida MYb11 and Pseudomonas fluorescens MYb115 protect the host against pathogens through distinct mechanisms. While P.
Barbara Pees, Lena Peters, Christian Treitz, Inga K. Hamerich, Kohar A. B. Kissoyan, Andreas Tholey, Katja Dierking   +6 more
doaj   +1 more source

Global Proteomic Response of Caenorhabditis elegans Against PemKSa Toxin

Frontiers in Cellular and Infection Microbiology, 2019
Bacterial exotoxins are major causative agents that infect by promoting cell and tissue damages through disabling the invading host immune system. However, the mode of action by which toxins modulate host immune system and lead cell death is still not ...
Dilawar Ahmad Mir, Krishnaswamy Balamurugan   +1 more
doaj   +1 more source