Immunoprecipitation of Proteins in Caenorhabditis elegans
Bio-Protocol, 2015 Immunoprecipitation (IP) is a biochemical technique to precipitate a protein out of solution using an antigen that can specifically bind to that protein.
Kevin Chan +3 more
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Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes. [PDF]
PLoS Biology, 2009 The nematode Caenorhabditis elegans is a popular model system in genetics, not least because a majority of human disease genes are conserved in C. elegans.
Sabine P Schrimpf +12 more
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The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones. [PDF]
PLoS Genetics, 2016 Protein AMPylation by Fic domain-containing proteins (Fic proteins) is an ancient and conserved post-translational modification of mostly unexplored significance. Here we characterize the Caenorhabditis elegans Fic protein FIC-1 in vitro and in vivo. FIC-
Matthias C Truttmann +5 more
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Nuclear/Cytoplasmic Fractionation of Proteins from Caenorhabditis elegans [PDF]
Bio-Protocol, 2018 C. elegans is widely used to investigate biological processes related to health and disease. To study protein localization, fluorescently-tagged proteins can be used in vivo or immunohistochemistry can be performed in whole worms.
Alejandro Mata-Cabana +3 more
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A proteomic analysis of lipid raft and GPI anchored proteins in Caenorhabditis elegans [PDF]
, 2010 Glycosylphosphatidylinositol (GPI) anchored proteins are a unique group of membrane proteins found on the surface and certain intracellular compartments of eukaryotic cells.
Rao, Wei
core +6 more sources
Revisiting the Small Heat Shock Protein Family in <i>Caenorhabditis elegans:</i> Insights from Phylogenetic, Structural, and Functional Analyses. [PDF]
MicroPubl BiolKamath R, Kasturi P.
europepmc +3 more sources
Proteome-based investigation of O-GlcNAcylation in a C. elegans model of ageing and Alzheimer's disease: Functional support for earlier hypothesis-generating findings. [PDF]
PLoS ONEO-linked N-acetylglucosamine (O-GlcNAc) is a post-translational modification of serine and threonine residues on nuclear and cytoplasmic proteins. The identity of O-GlcNAcylated proteins during ageing and neurodegenerative disease remains incompletely ...
Fernando Garcia Olivera
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Cell cycle checkpoints in Caenorhabditis elegans: the 14-3-3 gene par-5 is required for germline development and DNA damage response / Checkpoints del ciclo celular en Caenorhabditis elegans: el gen 14-3-3, par-5, es necesario para el desarrollo y respuesta al daño genómico de la línea germinal [PDF]
, 2012 [eng] 14-3-3 proteins have been extensively studied from yeast to mammals, and are associated with multiple roles ranging from fundamental processes such as cell cycle, apoptosis and stress response to diseases such as neurodegeneration and cancer ...
Aristizábal Corrales, David
core +6 more sources
Prereplication complex proteins get caught moonlighting
PLoS Biology, 2022 In this issue of PLOS Biology, Lattmann and colleagues report a new function for proteins of the DNA prereplication complex promoting the anchor cell to invade through the basement membrane and initiate vulval development in Caenorhabditis elegans.
Hilary A. Coller
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Identification and Functional Analysis of Cytokine-Like Protein CLEC-47 in Caenorhabditis elegans
mBio, 2021 A variety of effector proteins contribute to host defense in the nematode Caenorhabditis ...
Wen Pan +4 more
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