Results 11 to 20 of about 73,600 (228)
The astacin protein family inCaenorhabditis elegans [PDF]
European Journal of Biochemistry, 2003 In the nematodeCaenorhabditis elegans, 40 genes code for astacin‐like proteins (nematode astacins, NAS). The astacins are metalloproteases present in bacteria, invertebrates and vertebrates and serve a variety of physiological functions like digestion, hatching, peptide processing, morphogenesis and pattern formation.
Moehrlen, F., Hutter, H., Zwilling, R.
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BMC Genomics, 2021 Background F-box proteins represent a diverse class of adaptor proteins of the ubiquitin-proteasome system (UPS) that play critical roles in the cell cycle, signal transduction, and immune response by removing or modifying cellular regulators.
Ailan Wang, Wei Chen, Shiheng Tao
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American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
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Protein interactome mapping in Caenorhabditis elegans
Current Opinion in Systems Biology, 2019 The systematic identification of all protein-protein interactions that take place in an organism (the 'interactome') is an important goal in modern biology. The nematode Caenorhabditis elegans was one of the first multicellular models for which a proteome-wide interactome mapping project was initiated.
Remmelzwaal, Sanne, Boxem, Mike
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A systematic analysis of protein palmitoylation in Caenorhabditis elegans [PDF]
BMC Genomics, 2014 Palmitoylation is a reversible post-translational protein modification which involves the addition of palmitate to cysteine residues. Palmitoylation is catalysed by the DHHC family of palmitoyl-acyl transferases (PATs) and reversibility is conferred by palmitoyl-protein thioesterases (PPTs).
Edmonds, Matthew J, Morgan, Alan
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Curcumin reduced fat accumulation in Caenorhabditis elegans
Current Research in Food Science, 2021 Curcumin, the primary bioactive substance in turmeric, is known to be associated with weight loss. In this study, we employed Caenorhabditis elegans, a well-established in vivo nematode model to explore the role of curcumin in regulating lipid metabolism.
Yiren Yue +3 more
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Caenorhabditis elegans sperm membrane protein interactome [PDF]
Biology of Reproduction, 2018 The interaction and organization of proteins in the sperm membrane are important for all aspects of sperm function. We have determined the interactions between 12 known mutationally defined and cloned sperm membrane proteins in a model system for reproduction, the nematode Caenorhabditis elegans.
Marcello, Matthew R +2 more
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Scientific Reports, 2021 Alzheimer disease (AD) is a neurodegenerative disorder with an –as of yet– unclear etiology and pathogenesis. Research to unveil disease processes underlying AD often relies on the use of neurodegenerative disease model organisms, such as Caenorhabditis ...
Avgi E. Apostolakou +4 more
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Ecotoxicology and Environmental Safety, 2021 The aim of this study was to identify Gα proteins mediating function of neuronal G protein-coupled receptors (GPCRs) in controlling the response to polystyrene nanoparticles (PS-NPs).
Yunhan Yang, Qiuli Wu, Dayong Wang
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Caenorhabditis elegans BAH-1 is a DUF23 protein expressed in seam cells and required for microbial biofilm binding to the cuticle. [PDF]
PLoS ONE, 2009 The cuticle of Caenorhabditis elegans, a complex, multi-layered extracellular matrix, is a major interface between the animal and its environment. Biofilms produced by the bacterial genus Yersinia attach to the cuticle of the worm, providing an assay for
Kevin Drace +2 more
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