Results 191 to 200 of about 19,760,810 (228)
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A comparison of the antitumour activities of glucans and C. parvum.
Developments in biological standardization, 1978After i.v. injection of glucans (yeast cell walls, lentinan and pseudonigeran) into CBA mice, the peritoneal macrophages became cytostatic to R1 leukemia cells in vitro, and the mice showed resistance to lung nodule formation by i.v. injected T3 fibrosarcoma cells. The glucans were less active than C. parvum.
R, Bomford, C, Moreno
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Anticancer research, 1992
In vitro culture of murine spleen cells with Corynebacterium parvum (C. parvum) was found to induce lymphokine-activated killer (LAK)-like cells capable of killing both natural killer (NK)-sensitive and NK-resistant tumor cells as well as syngeneic macrophages (M phi). The induction of LAK-like activity by C.
M F, Chen, H, Suzuki, S, Yano
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In vitro culture of murine spleen cells with Corynebacterium parvum (C. parvum) was found to induce lymphokine-activated killer (LAK)-like cells capable of killing both natural killer (NK)-sensitive and NK-resistant tumor cells as well as syngeneic macrophages (M phi). The induction of LAK-like activity by C.
M F, Chen, H, Suzuki, S, Yano
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Radiation-Induced Inhibition of Splenocyte Locomotion and Its Protection by C. parvum
Radiation Research, 1978Normal C57/BL mice were stimulated by intraperitoneal (ip) injection of Corynebacterium parvum (CP) prior to sublethal whole-body or local (leg) irradiation.
Isac, M +5 more
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Evidence for granulocyte-mediated macrophage activation after C. parvum immunization
Cellular Immunology, 1983It has been previously demonstrated that at the peak of the peritoneal response to Corynebacterium parvum (Day 4), cytolytic macrophages can be characterized by the presence of intracellular bacteria. In the present study, the role of neutrophils in the activation of peritoneal macrophages by C. parvum was investigated.
Chapes, S K, Haskill, S
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Effect of C. parvum on intratumor immunity to the T1699 mammary adenocarcinoma.
The Journal of Immunology, 1980Abstract The mechanism of Corynebacterium parvum-induced tumor regression has been studied in the immunogenic murine T1699 adenocarcinoma model. Administration of C. parvum to animals bearing progressor tumors resulted in significant regression frequencies after both i.p. and intratumor (IT) injection.
S, Haskill, F, Ritter, S, Becker
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The occurrence of Cryptosporidium parvum and C. muris in wild rodents and insectivores in Spain
Veterinary Parasitology, 2000Five rodent and two insectivore species were investigated for Cryptosporidium at seven sites in north-eastern Spain. Of the 442 animals studied, 82 Apodemus sylvaticus, 1 A. flavicollis, 5 Mus spretus, 1 Rattus rattus, 8 Clethrionomys glareolus and 13 Crocidura russula were infected with only C. parvum. Eleven A. sylvaticus and 2 C.
J, Torres +4 more
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Effects of C. parvum on radiation response of murine tumors.
Developments in biological standardization, 1978The effects of intravenous C. parvum (CP) on the efficacy of fractionated gamma-irradiation in treating a fairly immunogenic fibrosarcoma (FSa) and a weakly immunogenic mammary carcinoma (MDAH-MCa-4) were studied in C3Hf/Bu mice. Tumors were 8 mm in diameter at the start of irradiation.
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Distribution of 3H-thymidine-labelled C. parvum in mice.
Developments in biological standardization, 1978Little is known of the localisation of injected Corynebacterium parvum. We therefore developed a method of radiolabelling this vaccine and determined its distribution in the mouse. Live C. parvum (Wellcome, strain CN 6134) was grown in the presence of 3H-thymidine and subsequently killed by formalin.
T E, Sadler, W A, Cramp, J E, Castro
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Effects of surgery and C. parvum on tumour metastases in mice.
Developments in biological standardization, 1978Surgical operations depress immune responses. The aim of this study was to observe the effects of operation (amputation) on the growth of the Lewis lung tumour and its metastases and to see if C. parvum counteracted them. Anaesthesia alone, or with amputation, did not affect the growth of the primary tumour but C. parvum depressed it.
J, Mosley, T E, Sadler, J E, Castro
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