Results 141 to 150 of about 103,895 (296)

ER‐Localized Deadenylase PNLDC1 Suppresses Colorectal Cancer Progression by Targeting the mRNA Decay of TUBB4B

Exploration, EarlyView.
The deficiency of PNLDC1 exacerbates the advancement of CRC. PNLDC1 interacts with TUBB4B mRNA to regulate the p53–p21–CDK2–cyclin E2 pathway, thereby influencing the G2/M phase of the cell cycle. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, highlighting the urgent need for novel therapeutic strategies.
Lexin Liu, Yuelin Guan, Yuzhou Qin, Guiping Chen, Guozhen Wang, Xiang Yan, Xue Li, Lei Sun, Wei Yu, Shi Ouyang, Zhichao Ma, Zihao Xu, Zhongkai Cao, Fan Yu, Tong Zhou, Ziyou Luo, Xiangjun Chen, Yongbin Yan, Lidan Hu   +18 more
wiley   +1 more source

Self-stretching molecular monolayers with autonomous folding and mechanical adaptation. [PDF]

Sci Adv
Iizuka T, Inoue S, Nikaido K, Tsuzuki S, Maki-Yonekura S, Hamaguchi T, Yonekura K, Hasegawa T.   +7 more
europepmc   +1 more source

Target validation and mode-of-action of C10, a broadly acting flavivirus capsid inhibitor

C10 was identified in a FACS-FRET-based screen designed to identify small compounds that interfere with HCV capsid protein (CP) interaction. Previous experiments demonstrated that C10 exhibited antiviral activity against all tested members of the ...
Dürrwald, Johanna
core   +1 more source

Phytochemistry, Chemotypic Diversity and Antimicrobial Potential of Essential Oils From Native Aromatic Plants of the Americas: A Systematic Review

Flavour and Fragrance Journal, EarlyView.
This review bridges ancestral indigenous knowledge with modern pharmacology, summarizing the phytochemistry and antimicrobial properties of essential oils from seven native American species. It highlights their significant activity against bacterial, fungal and parasitic pathogens, emphasizing their potential as sustainable therapeutic and agricultural
Arley Rey Páez, Mozaniel Santana de Oliveira, João Paulo Viana Leite   +2 more
wiley   +1 more source

Programming Intrinsic States of Solvent-Free Glycolipids through Molecular Architecture and Thermal History. [PDF]

ACS Omega
Kim W, Hogan DE, Maier RM, Kim M.
europepmc   +1 more source

Immersed Boundary Projection Method for Boundaries With Slip Velocities

International Journal for Numerical Methods in Fluids, EarlyView.
A formulation of the immersed boundary method for incompressible flow over arbitrarily‐shaped bodies with surface slip described by the Navier boundary condition is presented. The wall slip velocity and the boundary force are determined implicitly through a projection to satisfy both the boundary condition and the divergence‐free condition of the ...
Takehiro Fujii, Takeshi Omori
wiley   +1 more source

Self-assembly of sodium caprate in simulated intestinal fluids and with a therapeutic peptide: A small-angle neutron scattering study. [PDF]

Int J Pharm X
Akter S, Bergström LM, Hansson P, Kohlbrecher J, Doutch J, Hossain S, Larsson P.   +6 more
europepmc   +1 more source

Meniscus‐guided organic semiconductor single crystals: From fluid dynamics to morphology control and multifunctional applications

FlexMat, EarlyView.
Centered on the multiscale meniscus, this review dissects mass transport in meniscus‐guided coating into parallel and lateral components. By analyzing the balance of multiple factors during crystallization, it establishes a clear morphology‐performance relationship.
Yumeng Wang, Shengnan Chen, Lutong Guo, Lujing Shao, Zhenhua Li, Hao Liu, Yanlin Song, Yali Qiao   +7 more
wiley   +1 more source

Molecular Dynamics Study of CO₂-Induced Transfer of Crude Oil Components: Roles of Molecular Structure, Cohesion, and Mixture Composition. [PDF]

Molecules
Gao J, Wang M, Zhang Y, Lyu W, Zhang K, Zuo Z.   +5 more
europepmc   +1 more source

Challenges and strategies toward next‐generation high‐performance flexible and printable thin‐film transistors

FlexMat, EarlyView.
This review explores recent progress in printing strategies such as inkjet, screen, liquid metal, and roll to roll (R2R) methods and their roles in fabricating flexible TFTs. Device architectures are examined with emphasis on printed components and their influence on performance and stability.
Xia Zhao, Zhongqing Zeng, Zeyu Hu, Jaekyun Kim, Jidong Jin, Wensi Cai, Zhigang Zang   +6 more
wiley   +1 more source