Results 161 to 170 of about 265,300 (270)

Synthesis and structure of 2,4-bis-(2,6-dimethyl-4<i>H</i>-pyran-4-yl-idene)-3-oxo-penta-nedi-nitrile, an unexpected product of a Knoevenagel condensation reaction. [PDF]

Acta Crystallogr E Crystallogr Commun
Carella A, Parisi E, Piccialli V, Centore R.   +3 more
europepmc   +1 more source

Nanomagnetic Hyperthermia Sensitizes Gemcitabine Chemosensitivity in Pancreatic Cancer by Inhibiting HSPB1 to Amplify ACSL4‐Mediated Ferroptosis

Small, EarlyView.
ABSTRACT Pancreatic cancer, one of the most malignant solid tumors with the poorest prognosis, is commonly treated with gemcitabine (GEM)‐based systemic chemotherapy. However, chemoresistance remains a significant therapeutic challenge. Ferroptosis, a novel form of programmed cell death, has demonstrated exceptional susceptibility in chemoresistant ...
Jiaqiang Ren, Shuai Wu, Tong Su, Hugang Li, Jiachun Ding, Fan Chen, Jiantao Mo, Jie Li, Zheng Wang, Liang Han, Zheng Wu   +10 more
wiley   +1 more source

1-(4-Bromo-phen-yl)-4,5-diphenyl-2-(1<i>H</i>-pyrrol-2-yl)-1<i>H</i>-imidazole. [PDF]

IUCrdata
Nagaraj S, Loganathan N.
europepmc   +1 more source

Catalytic Scalable Synthesis of Polyketides Enabled by Chiral Brønsted Acid‐Catalyzed Asymmetric Allylborations

The Chemical Record, EarlyView.
The scalable synthesis of target molecules is crucial for applications such as biological evaluation in medicinal chemistry and even industrial production. We described recent advances in chiral Brønsted acid–catalyzed asymmetric allylboration, which enables access to previously elusive chiral building blocks, and highlight its application to the ...
Shigenobu Umemiya, Masahiro Terada
wiley   +1 more source

Consistent supra-molecular motif of <i>C</i>(7) O-H⋯O hydrogen-bonded chains and different local symmetries in three iso-indole-4-carb-oxy-lic acid derivatives. [PDF]

Acta Crystallogr E Crystallogr Commun
Alekseeva KA, Gurbanov AV, Tsiulina EN, Golubenkova AS, Akkurt M, Manahelohe GM.   +5 more
europepmc   +1 more source

Micronuclei and Other Nuclear Abnormalities in Patella Limpet as Biomarkers of Cytogenotoxicity in Recreational Port Waters

Environmental Toxicology, EarlyView.
ABSTRACT Over the past decades, the growth in human population and economic activities has led to an increase in maritime traffic. This rise puts additional pressure on marine environments, vessel fuel spills being considered to have a major impact on the ecosystem.
Carlos Valiente‐Diaz, Eva Garcia‐Vazquez, Verónica Soto‐López   +2 more
wiley   +1 more source

Cyclometalated Platinum Compounds from Competing C-H/C-X Bond Activation Pathways. [PDF]

ACS Omega
Anderson CM, Greenberg MW, LaFratta CN, Dziubelski M, Aleem Z, Hathaway BB, Tanski JM.   +6 more
europepmc   +1 more source

An engineered epididymal cell line provides a sustainable source of functional extracellular vesicles for in vitro sperm preservation: A multi‐omics and functional study

VIEW, EarlyView.
ABSTRACT This study investigated the function of epididymal extracellular vesicles (EVs) in overcoming sperm post‐testicular modification deficiencies. Although EVs derived from the epididymis play a crucial role in intercellular communication and molecular exchange, there is limited research addressing how EVs released by in vitro cultured epididymal ...
Long Li, Haonan Zhao, Yibo Li, Qixin Xu, Yang Zi, Tingting Chu, Heran Cao, Shujuan Liu, Zifang Wu, Huanqiang Zhao, Wuzi Dong   +10 more
wiley   +1 more source

Different inter-molecular inter-actions in solvated and unsolvated isatin-based di-thio-carbazate imine derivatives. [PDF]

Acta Crystallogr E Crystallogr Commun
McKay AP, Cordes DB, Fatah Abdul Manan MA.   +2 more
europepmc   +1 more source

Inhibition of PHF1 promotes ferroptosis via IRES‐dependent Snail translation regulation in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie, Shan Jin, Yao Zhan, Tiantian Du, Yaqi Dong, Peilong Li, Xiaoshi Zhang, Qiuchen Qi, Jie Gao, Chuanxin Wang   +9 more
wiley   +1 more source