Results 1 to 10 of about 48,951 (120)
Drosophila lacks C20 and C22 PUFAs [PDF]
Drosophila melanogaster has been considered a model organism for investigating human diseases and genetic pathways. Whether Drosophila is an ideal model for nutrigenomics, especially for FA metabolism, however, remains to be illustrated. The aim of this study was to examine the metabolism of C20 and C22 PUFAs in Drosophila.
Li Rong Shen +8 more
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C22 podovirus infectivity is associated with intermediate stiffness [PDF]
AbstractBacteriophages have potential for use as biological control agents (biocontrols) of pathogenic bacteria, but their low stability is limiting for their utilization as biocontrols. Understanding of the conditions conducive to storage of phages in which infectivity is maintained over long periods will be useful for their application as biocontrols.
Udom Sae-Ueng +7 more
openaire +2 more sources
Synthesis of (−)-Amphidinolide K Fragment C9−C22 [PDF]
AbstractFor Abstract see ChemInform Abstract in Full Text.
Thanos, Andreou +5 more
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Polyunsaturated fatty acids (PUFAs) have been extensively studied for their health benefits because they can be oxidized by lipoxygenases to form bioactive oxylipins. In this study, we investigated the impact of double bond placement on the kinetic properties and product profiles of human platelet 12-lipoxygenase (h12-LOX), human reticulocyte 15 ...
Michelle Tran +4 more
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Halichondrin B: Synthesis of the C1−C22 Subunit [PDF]
[Reaction: see text]. Two efficient routes to the C1-C22 subunit of halichondrin B are described. The cage ketal 7, which contains 11 asymmetric centers embedded within the ABCDEF-ring framework, was assembled from (+)-conduritol E (27) in 18 steps and 4% overall yield. In a separate route, 7 was also synthesized in 18 steps and 2% overall yield from a
William T, Lambert +3 more
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Structural and functional analysis of tomato sterol C22 desaturase [PDF]
Abstract Background Sterols are structural and functional components of eukaryotic cell membranes. Plants produce a complex mixture of sterols, among which β-sitosterol, stigmasterol, campesterol, and cholesterol in some Solanaceae, are the most abundant species.
Laura Gutiérrez-García +4 more
openaire +6 more sources
Synthesis of the C10−C22 Fragment of Marinisporolide A [PDF]
Treatment of glyoxal (2) with allyl bromide and SnCl2 (89%) followed by oxidative cleavage gave aldehyde 3 (Scheme 1). The reaction between alcohol 4 and PMB 2,2,2-trichloroacetimidate (PMBTCA) followed by Wacker oxidation provided the formation of methylketone 5 in 48% yield (2 steps).
Emílio Carlos de Lucca Júnior +1 more
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C22 disrupts embryogenesis and extends C. elegans lifespan
Caenorhabditis elegans is an instrumental model in aging research due to its large brood size, short lifespan, and malleable genetics. However, maintaining a synchronous nematode population for longevity studies is challenging and time consuming due to their quick rate of development and reproduction. Multiple methods are employed in the field, ranging
Safa Beydoun +5 more
openaire +3 more sources
Thermoresponsive C22 phage stiffness modulates the phage infectivity
AbstractBacteriophages offer a sustainable alternative for controlling crop disease. However, the lack of knowledge on phage infection mechanisms makes phage-based biological control varying and ineffective. In this work, we interrogated the temperature dependence of the infection and thermo-responsive behavior of the C22 phage.
Udom Sae-Ueng +7 more
openaire +3 more sources

