Results 1 to 10 of about 47,272 (187)

Loss of Acid Ceramidase in Myeloid Cells Protects From Chronic Colitis in IL10-Deficient Mice. [PDF]

FASEB J
Acid ceramidase converts ceramide to sphingosine which can then be converted to sphingosine‐1‐phosphate, a bioactive lipid involved in inflammation. Loss of acid ceramidase in myeloid cells protects from chronic colitis by reducing pro‐inflammatory markers, increasing ceramides, and reducing effector immune cells in the colon.
Espinoza KS, Dahl BK, Ryan EM, Gordon MR, Doll CL, Marron MT, Beard CA, Dey PD, Besselsen DG, Simpson RJ, Snider JM, Wilson JE, Kiela PR, Snider AJ.   +13 more
europepmc   +2 more sources

Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition. [PDF]

Cell Rep
Waters AM, Khatib TO, Papke B, Goodwin CM, Hobbs GA, Diehl JN, Yang R, Edwards AC, Walsh KH, Sulahian R, McFarland JM, Kapner KS, Gilbert TSK, Stalnecker CA, Javaid S, Barkovskaya A, Grover KR, Hibshman PS, Blake DR, Schaefer A, Nowak KM, Klomp JE, Hayes TK, Kassner M, Tang N, Tanaseichuk O, Chen K, Zhou Y, Kalkat M, Herring LE, Graves LM, Penn LZ, Yin HH, Aguirre AJ, Hahn WC, Cox AD, Der CJ.   +36 more
europepmc   +1 more source

Nr2f1a and Isl1 repress acquisition of epicardial identity in venous atrial cardiomyocytes. [PDF]

Development
Martin KE, Fernandes AT, Sayed M, Hanlon MA, Fallon S, Lim HW, Waxman JS.   +6 more
europepmc   +1 more source

Cell death analysis of inducible, titratable neurodegenerative disease models in zebrafish and human stem cell-derived retinal organoids. [PDF]

Dis Model Mech
Ceisel A, Graziano G, Emmerich K, Shi X, Kam TI, Flores-Bellver M, Vergara MN, Aparicio-Domingo S, Brenerman BM, Vielle A, Williams EM, Sharrock AV, Onuchuwku U, Martinez GS, Sanders LG, Nwagbo U, Wang B, Xiao H, Kroeschell G, Gao Y, Choe DJ, Clouatre CE, Carcoba DA, Reibman B, Rodriguez C, Yang K, Banerjee S, Matthews F, Thierer JH, Stein-O'Brien G, Dawson TM, Dawson VL, Ackerley DF, Canto-Soler MV, Zhang L, Mumm JS.   +35 more
europepmc   +1 more source

Problematic patterns of social media use increase with spontaneous cortical activity and transdiagnostic mental health symptoms in youth. [PDF]

Dev Cogn Neurosci
Petro NM, Webert LK, McDonald KM, Son JJ, Ward TW, Rice DL, Ende GC, Coutant AT, Steiner EL, Livermore CL, Schantell M, Killanin AD, Picci G, Wilson TW.   +13 more
europepmc   +1 more source

GenVarLoader: an accelerated dataloader for applying deep learning to personalized genomics. [PDF]

BMC Genomics
Laub D, Ho A, Raina L, Jaureguy J, Klie A, Salem RM, McVicker G, Carter H.   +7 more
europepmc   +1 more source

The Impact of Maternal Emotion Talk on an Early Intervention for Infants with Elevated Levels of Behavior Problems. [PDF]

Child Psychiatry Hum Dev
Goldhagen EL, Bagner DM, Lorenzo NE.
europepmc   +1 more source

E. coli RsmF activity depends on prior modification of 16S rRNA helix 44. [PDF]

Nucleic Acids Res
Barmada MI, Hanna A, Bair CR, McGinity EN, Zelinskaya N, Dey D, Conn GL.   +6 more
europepmc   +1 more source