Results 161 to 170 of about 206,211 (292)

Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract FAALs (fatty acyl‐AMP ligases) recruit and incorporate fatty acids during the biosynthesis of secondary metabolites. Their diversity, distribution, and substrate specificity remain poorly understood, which limits functional predictions from sequence data.
Anne Liong   +2 more
wiley   +1 more source

Control of Open Quantum Systems via Dynamical Invariants

open access: yesAdvanced Quantum Technologies, Volume 9, Issue 2, February 2026.
Dynamical invariants are used to reverse‐engineer control fields for open quantum systems described by time‐dependent Lindblad master equations. By minimizing an analytic leakage functional, the protocol dynamically steers the state along an effectively decoherence‐free path without costly iterative propagation.
Loris M. Cangemi   +4 more
wiley   +1 more source

Enriching Higher Affinity Aptamers by Addressing the Kinetic Aspect of the DNA Strand‐Displacement Reaction

open access: yesAngewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Capture‐SELEX for ampicillin aptamers led to the dominance of a low‐affinity aptamer, while extending the target‐library incubation time significantly increased the abundance of a high‐affinity aptamer, revealing a previously unrecognized kinetic effect in the DNA strand displacement reaction during SELEX.
Yuzhe Ding   +4 more
wiley   +2 more sources

Vibrational dynamics of a non-degenerate ultrafast rotor: the (C12,C13)-oxalate ion.

open access: yesJournal of Chemical Physics, 2013
D. Kuroda   +4 more
semanticscholar   +1 more source

Mechanistic Insights Into NFIX‐Mediated DNA Recognition and Transcriptional Regulation in Skeletal Muscle

open access: yesSmart Medicine, Volume 5, Issue 1, February 2026.
An atomic view of the NFIX–DNA complex reveals recognition of the TGGCA motif and links sequence‐specific binding to the transcriptional programs governing skeletal muscle development and disease. ABSTRACT Skeletal muscle is essential for voluntary movement and exhibits a remarkable capacity for regeneration following injury.
Ci Zhu   +11 more
wiley   +1 more source

Advances in the Development of Lipid Nanoparticles for mRNA Delivery

open access: yesSmall Structures, Volume 7, Issue 2, February 2026.
This review provides an integrated overview of mRNA–lipid nanoparticle (LNP) design, including lipid composition, scalable manufacturing, and structure–activity relationships. We highlight strategies for targeted delivery, physicochemical tuning, and high‐throughput screening such as DNA barcoding.
Xing Wang   +6 more
wiley   +1 more source

A Novel Link Between Electron Transport Chain Modulation and mcl‐PHA Production in Pseudomonas aeruginosa 5300 Using Azide as a Modulator

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
The oleic acid and azide inhibited the cytochrome c oxidase activity in Pseudomonas aeruginosa MCC 5300, shifting the electron flux towards bd‐oxidase. This resulted in more NADH consumption to maintain the proton gradient for energy generation. The rapid depletion of NADH triggered high mcl‐PHA accumulation.
Raghavendra Paduvari   +1 more
wiley   +1 more source

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