Results 191 to 200 of about 378,392 (246)

Case report of an occipital neuralgia caused by a vertebral artery loop: surgical strategies from a rare neurovascular conflict. [PDF]

Front Surg
Haemmerli J, Fabrizio MP, Najafi A, Grüner A, Alfieri A.   +4 more
europepmc   +1 more source

AI‐Assisted Digital Single‐Molecule Activity Tracker for Decoupling Intrinsic Heterogeneity from Photo‐Oxidative Damage in High‐Photon‐Flux Enzymology

Advanced Science, EarlyView.
Employing a digital single‐molecule activity tracker (dSMAT), this research demonstrates that high‐photon‐flux irradiation drives progressive oxidative scarring in polymerases. Unlike simple thermal denaturation, real‐time kinetic tracking dynamically visualizes enzymes degrading into multiple impaired subpopulations.
Anran Zheng, Qi Yang, Jinze Li, Fuqiang Ma, Xuefeng Wang, Zhen Guo, Chuanyu Li, Dongshu Li, Jia Yao, Zhiqi Zhang, Wei Zhang, Lianqun Zhou   +11 more
wiley   +1 more source

Exploring Biomarkers and Mechanisms of Action of Adaptive Immune Response in Age-Related Macular Degeneration Based on Transcriptomics. [PDF]

Biomedicines
Xiong C, Zhou S, Hu Y, Xu X.
europepmc   +1 more source

Use of the “Ru‐1O2‐Hydrazide” System Catalyzed by Metallic Ruthenium Complexes to Decipher the Interaction Between Microbes and Host Cancer Cells

Advanced Science, EarlyView.
ABSTRACT The dynamic interplay between bacteria and host cancer cells plays a critical role in tumor microenvironment modulation, bacterial pathogenesis, and potential oncotherapy applications. However, traditional methods often fail to capture transient or spatially restricted molecular interactions at the bacteria‐cancer cell interface.
Amin Sun, Kaihong Wang, Haifu Sun, Kemei Tao, Xiang Li, Xiuhua Zhao, Shuang Qiu   +6 more
wiley   +1 more source

The Complosome: An Emerging Intracellular Complement Network in Cancer Development and Therapy. [PDF]

Int J Mol Sci
Zadroga Ł, Lewandowski F, Bębnowska D, Majchrzak A, Czyż A, Niedźwiedzka-Rystwej P.   +5 more
europepmc   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

Crystal structure of (3<i>R</i>,5a<i>S</i>,6<i>R</i>,9<i>R</i>,12<i>R</i>,12a<i>R</i>)-3,6,9-tri-methyl-deca-hydro-12<i>H</i>-3,12-ep-oxy[1,2]dioxepino[4,3-<i>i</i>]isochromen-10-yl 5-((3a<i>S</i>,4<i>S</i>,6a<i>R</i>)-2-oxohexa-hydro-1<i>H</i>-thieno[3,4-<i>d</i>]imidazol-4-yl)penta-noate. [PDF]

Acta Crystallogr E Crystallogr Commun
Yang X, Chen S, Liu W, Cui M, Zhao Q.
europepmc   +1 more source

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History Studies International Journal of History, 2018
openaire   +1 more source

Super‐Resolution and High‐Data‐Density Acoustic Meta‐Hologram via Amplitude and Phase Coupling

Advanced Science, EarlyView.
A super‐resolution acoustic meta‐hologram utilizes amplitude‐phase coupling under energy conservation constraints to overcome the traditional diffraction limit. This conceptually advanced approach achieves high‐fidelity acoustic field reconstruction and dense information transmission, unlocking new potentials for high‐resolution acoustic imaging and ...
Xiao Guo, Xinzong Wang, Guoshen Tang, Haohan Zeng, Siqi Fan, Xinghao Hu, Youyu Mo, Zhenyu He, Tingting Li, Hui Xu, Jiao Shen, Haiyan Fan, Xiaoxiang Gao, Yifan Zhu, Hui Zhang, Badreddine Assouar   +15 more
wiley   +1 more source