Results 251 to 260 of about 2,856,075 (328)

El depósito de C3 en la glomerulonefritis extracapilar de tipo iii condiciona un mal pronóstico

, 2017
Marina Sánchez-Agesta Martínez, Cristina Rabasco Ruiz, Rafael Sánchez‐Sánchez, Rosa Ortega Salas, María López Andreu, Pedro Aljama García, Mario Espinosa Hernández   +6 more
openalex   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

C3 mutations and poor pegcetacoplan response in paroxysmal nocturnal hemoglobinuria. [PDF]

Front Immunol
Rodríguez de Córdoba S, Reparaz Suevos A, González Sanz S, Fernández FJ, Vega MC, Varela EC, Lada Colunga A, Vallejo Llamas JC, Gonzalez-Rodríguez AP.   +8 more
europepmc   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Low complement items play different roles on the classification performance of SLICC-2012, EULAR/ACR-2019, and SLERPI. [PDF]

Front Med (Lausanne)
Chen S, Zhang L, Yan M, Li S, Xue L, Tang M.   +5 more
europepmc   +1 more source

All‐Round Talent: Unique Zinc Guanidine Catalyst Performs Efficiently in Synthesis and Chemical Recycling of (Bio)Polyesters

Advanced Science, EarlyView.
A new zinc hybrid guanidine catalyst [Zn{(R,R)TMGNMe2(1,2)ch}2](OTf)2 (C1) shows very high catalytic activity in the polymerization of cyclic esters and in the depolymerization of these polyesters. Using C1 in the ring‐opening polymerization of lactide and caprolactone under industrially relevant conditions, astonishing rate constants of the same order
Tabea Becker, Koki Takeuchi, Carolin Süßmuth, Frederico Boekhoff, Martin A. Schäfer, Shunsuke Kato, Alexander Hoffmann, Takashi Hayashi, Sonja Herres‐Pawlis   +8 more
wiley   +1 more source

Conception de nouveaux catalyseurs de symétrie C3 pour la valorisation chimique du CO2

, 2017
Benjamin Bousquet
openalex   +1 more source

CREATION OF THE IMMUNOFERMENTIC TEST SYSTEM FOR DETECTING C3 COMPLEX COMPONENT WITH THE USE OF PEPTIDOGLYCAN

, 2018
S. S. Andina, Е. А. Шмелева, A. E. Vershinin, Л. А. Краева   +3 more
openalex   +2 more sources

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

Synthesis, crystal structure, Hirshfeld surface and DFT analysis of bis-(4-oxo-4-phenyl-but-2-en-2-olato-κ² <i>O</i>,<i>O</i>')copper(II). [PDF]

Acta Crystallogr E Crystallogr Commun
Siddikova K, Murodov S, Ziyatov D, Jabbarova D, Ashurov J, Daminova S.   +5 more
europepmc   +1 more source