Results 261 to 270 of about 2,856,075 (328)

Design,Synthesis, and Biological Evaluation of aNovel Long-Acting Human Complement C3 Inhibitor Synthesized via thePASylation–Lipidation Modular (PLM) Platform

Chengcheng Wang (668359), Yapeng Wang (692803), Yu Duan (426008), Yuanzhen Dong (11284302), Haoju Hua (17535590), Huixin Cui (21366799), Shuaiyi Huang (21366802), Zongqing Huang (18333860), Jianguang Lu (9632081), Chunyong Ding (1804177), Zhengyan Cai (1944772), Jun Feng (116162)   +11 more
openalex   +1 more source

Regiodivergent N1- and C3- Carboxylation of Indoles [PDF]

Xia Liu, Zhi Li, Congman Song, Guiqing Xu, Duanyang Kong   +4 more
openalex   +1 more source

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

Advanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu, Jiaxin Zhang, Xiangyu Yan, Nuo Li, Yu‐Chao Dong, Zihao Wang, Daowei Li, Yong Du, Huan Wang   +8 more
wiley   +1 more source

Environmentally adjusted <i>δ</i> ¹³C thresholds for accurate detection of C₄ plant consumption in Europe. [PDF]

Commun Earth Environ
Depaermentier MLC, Kempf M, Motuzaitė Matuzevičiūtė G.   +2 more
europepmc   +1 more source

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

g-C₃N₄/CoN₄ heterojunction as a sensor for detecting volatile organic compounds: a density functional study. [PDF]

RSC Adv
Dhilshada VN, Shilpa M, Chattopadhyaya M.   +2 more
europepmc   +1 more source

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History Studies International Journal of History, 2018
openaire   +1 more source

CD81+ senescent-like fibroblasts exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis

Liangliang Fu, Chenghu Yin, Zhao Qin, Shuling Guo, Wenjun Shao, Ting Xia, Quan Sun, Liangwen Chen, Jinghan Li, Min Wang, Haibin Xia   +10 more
openalex   +1 more source

%c3%96%c4%9fretmen%20Adaylar%c4%b1n%c4%b1n%20%c3%96zel%20G%c3%b6relilik%20Konusundaki%20Bilgi%20D%c3%bczeylerinin%20%c3%87e%c5%9fitli%20De%c4%9fi%c5%9fkenler%20A%c3%a7%c4%b1s%c4%b1ndan%20%c4%b0ncelenmesi

, 2018
Tuğba TAŞKIN, Şebnem Kandil İngeç
openalex   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source